Hematologic Malignancy
Leukemic Phase of Non-Hodgkin Lymphoma
CI-CAN-00003025Explore in graph →
Hematologic12 active trials1 evidence items
- NCIt
- C8594
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Hematologic Malignancy
CI-CAN-00003025Explore in graph →
Variants & evidence
1 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CD28 Fusion1 | ||||||||
| Ipilimumab | Sezary SyndromeALIAS | Predictive | C | Supports Sensitivity Response | 2 | accepted | EID1520A 67-year-old Caucasian female with stage IVA Sezary syndrome presented refractory to traditional therapy and was enrolled in a whole genome study trial. Sequencing revealed a CTLA4-CD28 fusion protei… (full text at CIViC) PMID 25802883 · Sekulic et al., 2015 · Open in CIViC | civic |
Data updated 22 hours agoSource updated unknownsource: civic (CC0)
Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.