Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,846 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,846 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05328908 | A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer(RELATIVITY-123) | terminated | Phase 3 | 769 | Bristol-Myers SquibbINDUSTRY | 22 | Aug 26, 2026 | clinicaltrials |
| NCT07152821 | Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma(BATTMAN) | terminated | Phase 3 | 21 | Canadian Cancer Trials GroupNETWORK |
| 1 |
| Jul 16, 2026 |
| clinicaltrials |
| NCT03426371 | Epidermal Growth Factor Receptor (EGFR) Antagonist Chimeric Anti-EGFR Monoclonal Antibody Trial | terminated | Phase 3 | 52 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd.INDUSTRY | 1 | May 12, 2026 | clinicaltrials |
| NCT04856787 | A Clinical Studyf of SHR-1701 or Placebo in Combination With BP102 and XELOX in the First-line Treatment of mCRC | terminated | Phase 2 / Phase 3 | 62 | Suzhou Suncadia Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | May 18, 2025 | clinicaltrials |
| NCT02467582 | Adjuvant Aspirin Treatment for Colon Cancer Patients | terminated | Phase 3 | 1,040 | Swiss Cancer InstituteOTHER | 4 | May 16, 2025 | clinicaltrials |
| NCT04316013 | Volatile Anaesthesia and Perioperative Outcomes Related to Cancer: the VAPOR-C Trial | terminated | Phase 3 | 254 | Peter MacCallum Cancer Centre, AustraliaOTHER | 3 | Mar 14, 2025 | clinicaltrials |
| NCT01167725 | Standard Therapy With or Without Surgery and Mitomycin C in Treating Patients With Advanced Limited Peritoneal Dissemination of Colon Cancer | terminated | Phase 3 | 340 | Alliance for Clinical Trials in OncologyOTHER | 1 | Dec 27, 2024 | clinicaltrials |
| NCT04607668 | Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer (mCRC):(PRESERVE1) | terminated | Phase 3 | 326 | G1 Therapeutics, Inc.INDUSTRY | 8 | Nov 26, 2024 | clinicaltrials |
| NCT05223673 | Phase 3 Study of Futuximab/Modotuximab in Combination With Trifluridine/Tipiracil Versus Trifluridine/Tipiracil Single Agent in Participants With Previously Treated Metastatic Colorectal Cancer(COLSTAR) | terminated | Phase 3 | 7 | Institut de Recherches Internationales ServierOTHER | 6 | Aug 20, 2024 | clinicaltrials |
| NCT03500874 | Adjuvant Systemic Chemotherapy With or Without HAI-FUDR in Patients With Resected CRLM | terminated | Phase 3 | 92 | Sun Yat-sen UniversityOTHER | 1 | Jan 22, 2024 | clinicaltrials |
| NCT01011478 | Rosuvastatin in Treating Patients With Stage I or Stage II Colon Cancer That Was Removed By Surgery | terminated | Phase 3 | 406 | NSABP Foundation IncNETWORK | 2 | Aug 16, 2023 | clinicaltrials |
| NCT00303628 | Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal Cancer | terminated | Phase 3 | 355 | ECOG-ACRIN Cancer Research GroupNETWORK | 4 | Jul 6, 2023 | clinicaltrials |
| NCT00002525 | Perioperative Chemotherapy in Treating Patients With Colon Cancer That Can Be Surgically Removed | terminated | Phase 3 | 859 | ECOG-ACRIN Cancer Research GroupNETWORK | 1 | Jun 28, 2023 | clinicaltrials |
| NCT03678428 | FUDR/Oxaliplatin HAI Plus Irinotecan vs. FOLFOXIRI Chemotherapy in Treating Initially Unresectable CRCLM | terminated | Phase 3 | 92 | Sun Yat-sen UniversityOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT03827044 | Avelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer(POLEM) | terminated | Phase 3 | 30 | Royal Marsden NHS Foundation TrustOTHER | 1 | Oct 7, 2022 | clinicaltrials |
| NCT03970694 | Neoadjuvant Chemoradiotherapy Versus Neoadjuvant Chemotherapy For Unresectable Locally Advanced Colon Cancer | terminated | Phase 3 | 49 | Sun Yat-sen UniversityOTHER | 1 | Jun 8, 2022 | clinicaltrials |
| NCT03475680 | Mechanical Bowel Preparation and Oral Antibiotics Before Colon Cancer Surgery(COLONPREP) | terminated | Phase 3 | 193 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | May 17, 2022 | clinicaltrials |
| NCT02588248 | L-Menthol Injection as a Novel Technique During Colonoscopy(MINT-C) | terminated | Phase 3 | 82 | University Hospitals Cleveland Medical CenterOTHER | 1 | Apr 19, 2022 | clinicaltrials |
| NCT02664077 | A Study Evaluating Regorafenib Following Completion of Standard Chemotherapy for Patients With Colon Cancer(ARGO) | terminated | Phase 3 | 34 | NSABP Foundation IncNETWORK | 1 | Apr 14, 2022 | clinicaltrials |
| NCT04034355 | Preventive Treatment of OxaLiplatin Induced peripherAl neuRopathy in Adjuvant Colorectal Cancer(POLAR-A) | terminated | Phase 3 | 301 | Egetis TherapeuticsINDUSTRY | 10 | Jan 26, 2022 | clinicaltrials |
| NCT03654729 | Preventive Treatment of Oxaliplatin Induced Peripheral Neuropathy in Metastatic Colorectal Cancer (POLAR-M)(POLAR-M) | terminated | Phase 3 | 291 | Egetis TherapeuticsINDUSTRY | 13 | Dec 17, 2021 | clinicaltrials |
| NCT01767857 | A Phase III Study of Xilonix in Patients With Advanced Colorectal Cancer(XCITE) | terminated | Phase 3 | 643 | Janssen Research & Development, LLCINDUSTRY | 13 | Jun 29, 2021 | clinicaltrials |
| NCT01437514 | Effective Study of Preoperative Short-course Radiotherapy for the Advanced Resectable Rectal Cancer | terminated | Phase 2 / Phase 3 | 410 | West China HospitalOTHER | 1 | Jun 7, 2021 | clinicaltrials |
| NCT03158610 | Biological-guided Metronomic Chemotherapy as Maintenance Strategy in Metastatic Colorectal Cancer | terminated | Phase 2 / Phase 3 | 20 | Ruijin HospitalOTHER | 1 | May 3, 2021 | clinicaltrials |
| NCT01318161 | Epidural Versus Patient-controlled Analgesia for Reduction in Long-term Mortality Following Colorectal Cancer Surgery(EPICOL) | terminated | Phase 3 | 221 | Örebro University, SwedenOTHER | 1 | Feb 16, 2021 | clinicaltrials |
| NCT00023868 | Combination Chemotherapy With or Without Chemoembolization in Treating Patients With Colorectal Cancer Metastatic to the Liver (6655) | terminated | Phase 3 | — | American College of Radiology Imaging NetworkNETWORK | 1 | Dec 2, 2020 | clinicaltrials |
| NCT02453490 | Compare Efficacy and Safety of Raltitrexed-based and 5fu-based Neoadjuvant Chemotherapy for Colorectal Liver Metastasis | terminated | Phase 3 | 360 | Zhejiang UniversityOTHER | 1 | Jul 14, 2020 | clinicaltrials |
| NCT03300609 | 5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumab | terminated | Phase 3 | 4 | University of Southern CaliforniaOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT00207831 | Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma(UFT RT Phase 3) | terminated | Phase 3 | 219 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT00544700 | Bevacizumab in Treating Patients Who Have Undergone First-Line Therapy for Metastatic Colorectal Cancer | terminated | Phase 3 | 265 | Swiss Cancer InstituteOTHER | 1 | Feb 20, 2020 | clinicaltrials |
| NCT01902823 | Effect of Cancer Nurse Navigators on Patient Outcomes | terminated | Phase 2 / Phase 3 | 16 | University of Wisconsin, MadisonOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT00078897 | Selenium for Prevention of Adenomatous Colorectal Polyps | terminated | Phase 3 | 1,621 | University of ArizonaOTHER | 1 | Sep 24, 2019 | clinicaltrials |
| NCT02605044 | Masitinib in Combination With FOLFIRI for Second-line Treatment of Patients With Metastatic Colorectal Cancer | terminated | Phase 3 | 123 | AB ScienceINDUSTRY | 3 | Feb 11, 2019 | clinicaltrials |
| NCT00254436 | A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients | terminated | Phase 3 | 50 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 25, 2018 | clinicaltrials |
| NCT01842971 | ALPPS (Liver Partition and Portal Vein Ligation) for Two-stage Hepatectomy for Colorectal Liver Metastasis | terminated | Phase 3 | 3 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Aug 2, 2018 | clinicaltrials |
| NCT00077233 | FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum | terminated | Phase 3 | 238 | Alliance for Clinical Trials in OncologyOTHER | 1 | May 16, 2018 | clinicaltrials |
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT01279681 | Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer | terminated | Phase 3 | 32 | Alliance for Clinical Trials in OncologyOTHER | 0 | Dec 8, 2017 | clinicaltrials |
| NCT01939223 | Colorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudy(COAST) | terminated | Phase 3 | 25 | BayerINDUSTRY | 14 | Oct 20, 2017 | clinicaltrials |
| NCT01309126 | Study of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal Cancer(PRIMUS) | terminated | Phase 3 | 217 | HiberCell, Inc.INDUSTRY | 4 | Jul 13, 2017 | clinicaltrials |
| NCT02060669 | Xeloda Maintenance Versus BSC in Metastatic Colorectal Cancer | terminated | Phase 3 | 10 | Samsung Medical CenterOTHER | 1 | Apr 27, 2017 | clinicaltrials |
| NCT02266849 | Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study | terminated | Phase 3 | 12 | Odense University HospitalOTHER | 1 | Oct 11, 2016 | clinicaltrials |
| NCT01233544 | Radiofrequency Ablation Versus Stereotactic Radiotherapy in Colorectal Liver Metastases(RAS01) | terminated | Phase 3 | 300 | University of AarhusOTHER | 2 | May 12, 2016 | clinicaltrials |
| NCT00603577 | Role of Xaliproden on Recovery Rate From Severe Neuropathy in Patients Who Have Completed Adjuvant Chemotherapy With Oxaliplatin Based Regimens(XENON) | terminated | Phase 3 | 102 | SanofiINDUSTRY | 8 | May 5, 2016 | clinicaltrials |
| NCT00305643 | Celecoxib in Preventing Hand/Foot Syndrome Caused By Capecitabine With Metastatic Breast or Colorectal Cancer | terminated | Phase 3 | 11 | M.D. Anderson Cancer CenterOTHER | 2 | Dec 24, 2015 | clinicaltrials |
| NCT00396487 | Tailored Treatment in Metastatic Colorectal Cancer | terminated | Phase 3 | 1 | Vejle HospitalOTHER | 1 | Jun 11, 2015 | clinicaltrials |
| NCT00720512 | Second-Line Combination Chemotherapy With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer Who Have Received First-Line Chemotherapy and Bevacizumab(BEBYP) | terminated | Phase 3 | 184 | Gruppo Oncologico del Nord-OvestOTHER | 1 | Mar 11, 2015 | clinicaltrials |
| NCT00499369 | Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic Colorectal Cancer That Progressed During First-Line Therapy | terminated | Phase 3 | 72 | National Cancer Institute (NCI)NIH | 1 | Jul 31, 2014 | clinicaltrials |
| NCT00394992 | Adjuvant Xeloda Plus Eloxatin +/- Avastin After Radical Resection of Liver Metastasis of Colorectal Cancer | terminated | Phase 3 | 79 | Dutch Colorectal Cancer GroupOTHER | 1 | Feb 4, 2014 | clinicaltrials |
| NCT00268463 | Oxaliplatin and Capecitabine With or Without an Hepatic Arterial Infusion With Floxuridine in Treating Patients Who Are Undergoing Surgery and/or Ablation for Liver Metastases Due to Colorectal Cancer | terminated | Phase 3 | 22 | NSABP Foundation IncNETWORK | 1 | May 15, 2013 | clinicaltrials |
Data updated 22 days agoSource updated Aug 26, 2026source: clinicaltrials