Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04503694 | Neoadjuvant Regorafenib in Combination With Nivolumab and Short-course Radiotherapy in Stage II-III Rectal Cancer(REGINA) | active not recruiting | Phase 2 | 72 | Jules Bordet InstituteOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT05239741 | Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66) | active not recruiting | Phase 3 | 100 | Merck Sharp & Dohme LLCINDUSTRY | 1 | May 22, 2026 |
| clinicaltrials |
| NCT05571293 | Combination Immunotherapy in Colorectal Cancer(NEST-1) | active not recruiting | Phase 2 | 26 | Weill Medical College of Cornell UniversityOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT07587619 | Intraoperative Use of Oxygen Saturation Imaging to Assess Intestinal Perfusion | active not recruiting | Phase 1 / Phase 2 | 52 | University of Southern CaliforniaOTHER | 1 | May 20, 2026 | clinicaltrials |
| NCT03386500 | Safety Study of BMX-001 (Radio-protector) in Patients With Newly Diagnosed Anal Cancer | active not recruiting | Phase 1 / Phase 2 | 24 | University of NebraskaOTHER | 1 | May 18, 2026 | clinicaltrials |
| NCT05462717 | Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors | active not recruiting | Phase 1 | 222 | Revolution Medicines, Inc.INDUSTRY | 13 | May 15, 2026 | clinicaltrials |
| NCT06043947 | Survival Monitoring in Russian Cancer Registries(SURVIMON) | active not recruiting | — | 100,000 | N.N. Petrov National Medical Research Center of OncologyOTHER | 1 | May 15, 2026 | clinicaltrials |
| NCT04136002 | Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode(ECLIPSE) | active not recruiting | — | 44,467 | Guardant Health, Inc.INDUSTRY | 1 | May 14, 2026 | clinicaltrials |
| NCT05652894 | A Study of HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer | active not recruiting | Phase 3 | 190 | Taizhou Hanzhong biomedical co. LTDINDUSTRY | 1 | May 14, 2026 | clinicaltrials |
| NCT05877352 | Intraoperative Electron Radiotherapy in Rectal Cancer - A Feasibility Trial(ELECTRA) | active not recruiting | N/A | 31 | University Hospital Southampton NHS Foundation TrustOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT04314401 | National Cancer Institute "Cancer Moonshot Biobank" | active not recruiting | — | 1,600 | National Cancer Institute (NCI)NIH | 2 | May 13, 2026 | clinicaltrials |
| NCT05694936 | Combining Sodium Valproate With Standard-of-care EGFR (Epidermal Growth Factor Receptor) Monoclonal Antibody Treatment in Patients With Metastatic Colorectal Cancer | active not recruiting | Phase 2 | 38 | Australasian Gastro-Intestinal Trials GroupNETWORK | 1 | May 8, 2026 | clinicaltrials |
| NCT05862051 | RESOLUTE Trial Aims to Investigate the Value of Adding Local Ablative Treatment to Standard Systemic Treatment for Unresectable Oligometastatic Colorectal Cancer(RESOLUTE) | active not recruiting | N/A | 6 | Australasian Gastro-Intestinal Trials GroupNETWORK | 1 | May 8, 2026 | clinicaltrials |
| NCT04713618 | Changes in Pelvic Health, Sexual Function, and Quality of Life in Women With Pelvic Cancer Undergoing Radiation Therapy(GEORGIA) | active not recruiting | — | 72 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | May 7, 2026 | clinicaltrials |
| NCT04430725 | Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study | active not recruiting | — | 74 | M.D. Anderson Cancer CenterOTHER | 1 | May 5, 2026 | clinicaltrials |
| NCT03637686 | IMPROVE: Circulating Tumor DNA Analysis to Optimize Treatment for Patients With Colorectal Cancer | active not recruiting | — | 3,182 | University of AarhusOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT05961709 | The Phoenix Trial: Phase II Trial of Cemiplimab for the Non-operative Management of Localized dMMR Colon Cancer | active not recruiting | Phase 2 | 50 | M.D. Anderson Cancer CenterOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT07564908 | Correlation and Heterogeneity of the Immune Microenvironment and Histopathological Growth Patterns in Resectable Colorectal Cancer Liver Metastases(CRLM) | active not recruiting | — | 64 | Meng QiuOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT07565831 | Study on the Prediction of Regional Lymph Node Metastasis in Colorectal Cancer by Spectral CT Combined With MSI | active not recruiting | N/A | 260 | Yunnan Cancer HospitalOTHER | 1 | May 4, 2026 | clinicaltrials |
| NCT01558921 | Rectal Cancer And Pre-operative Induction Therapy Followed by Dedicated Operation. The RAPIDO Trial(RAPIDO) | active not recruiting | Phase 3 | 920 | University Medical Center GroningenOTHER | 7 | May 1, 2026 | clinicaltrials |
| NCT06441487 | mPATH-Cloud for Colorectal Cancer Screening(mPATH-Cloud) | active not recruiting | N/A | 1,062 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Apr 30, 2026 | clinicaltrials |
| NCT04084249 | ctDNA-guided Surveillance for Stage III CRC, a Randomized Intervention Trial | active not recruiting | N/A | 359 | Claus Lindbjerg AndersenOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT06040632 | IMPROVE-pT1: Accurate Allocation of Completion Resection in Early Colorectal Cancer | active not recruiting | — | 67 | University of AarhusOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT06628388 | Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong(JCDATAZONEWH) | active not recruiting | N/A | 1,728 | The University of Hong KongOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT07555639 | An Integrated Genomic Approach to Assess Genetic Risk and Drug Sensitivity(GERSOM) | active not recruiting | N/A | 4,000 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT05953662 | Safety and Efficacy of Reduced-port Laparoscopic Surgery for Patients Of Colon and Upper Rectal Cancer | active not recruiting | N/A | 500 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Apr 27, 2026 | clinicaltrials |
| NCT03141437 | Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer | active not recruiting | N/A | 130 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT05638542 | Comparison of Expression of Carcinogenesis-related Molecular Markers in the Patients With Colon Cancer and Polyp | active not recruiting | — | 582 | Seoul National University Bundang HospitalOTHER | 1 | Apr 24, 2026 | clinicaltrials |
| NCT05005117 | Laparoscopic Approach for Emergency Colon Resection | active not recruiting | N/A | 192 | Joint Authority for Päijät-Häme Social and Health CareOTHER | 1 | Apr 22, 2026 | clinicaltrials |
| NCT04544046 | Supportive Oncology Care At Home RCT | active not recruiting | N/A | 300 | Massachusetts General HospitalOTHER | 1 | Apr 21, 2026 | clinicaltrials |
| NCT07522294 | Optimization and Standardization of Single-Port Robotic Transanal Minimally Invasive Surgery for Rectal Tumor Excision | active not recruiting | N/A | 20 | Jeng-Fu YouOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT07523763 | Neoadjuvant Low-dose Immunotherapy in Locally Advanced MMR-deficient Colorectal Cancer(NIVO1002024) | active not recruiting | Phase 2 | 30 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Apr 17, 2026 | clinicaltrials |
| NCT02863107 | Young-Onset Colorectal Cancer | active not recruiting | — | 818 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT03157128 | A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)(LIBRETTO-001) | active not recruiting | Phase 1 / Phase 2 | 857 | Eli Lilly and CompanyINDUSTRY | 16 | Apr 16, 2026 | clinicaltrials |
| NCT03144765 | Multicenter Phase II Study of Transanal TME (taTME) | active not recruiting | N/A | 100 | Icahn School of Medicine at Mount SinaiOTHER | 2 | Apr 15, 2026 | clinicaltrials |
| NCT00119912 | NORCCAP: Norwegian Colorectal Cancer Prevention Trial(NORCCAP) | active not recruiting | N/A | 100,000 | Norwegian Institute of Public HealthOTHER_GOV | 1 | Apr 14, 2026 | clinicaltrials |
| NCT01538550 | Pilot Study of a National Screening Programme for Bowel Cancer in Norway | active not recruiting | N/A | 140,000 | Norwegian Institute of Public HealthOTHER_GOV | 1 | Apr 14, 2026 | clinicaltrials |
| NCT02688712 | ExIST Study of LY2157299 (Galunisertib) in Rectal Cancer | active not recruiting | Phase 2 | 50 | Providence Health & ServicesOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT06417476 | Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer | active not recruiting | Phase 2 | 66 | Pei-Rong DingOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT06865521 | Akkermansia Probiotics Plus Anti-PD-1 Monoclonal Antibody in MSS/pMMR Advanced Colorectal Cancer | active not recruiting | N/A | 22 | West China HospitalOTHER | 1 | Apr 13, 2026 | clinicaltrials |
| NCT00579514 | Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients | active not recruiting | N/A | 21,081 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 7, 2026 | clinicaltrials |
| NCT03678883 | 9-ING-41 in Patients With Advanced Cancers | active not recruiting | Phase 2 | 350 | Actuate Therapeutics Inc.INDUSTRY | 7 | Apr 3, 2026 | clinicaltrials |
| NCT04245865 | Tocotrienol and Bevacizumab in Metastatic Colorectal Cancer(Toco-CoR) | active not recruiting | Phase 2 | 83 | Vejle HospitalOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT07509632 | Predicting Pathological Complete Response in Rectal Cancer Using Machine Learning | active not recruiting | — | 320 | Peking University People's HospitalOTHER | 1 | Apr 3, 2026 | clinicaltrials |
| NCT01349881 | S0820, Adenoma and Second Primary Prevention Trial(PACES) | active not recruiting | Phase 3 | 354 | SWOG Cancer Research NetworkNETWORK | 1 | Apr 2, 2026 | clinicaltrials |
| NCT05108428 | Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma | active not recruiting | Early Phase 1 | 20 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Apr 1, 2026 | clinicaltrials |
| NCT04963283 | Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer | active not recruiting | Phase 2 | 48 | University of Colorado, DenverOTHER | 1 | Mar 31, 2026 | clinicaltrials |
| NCT07494578 | Observational Study Regarding the Combination of Fluoropyrimidine and Bevacizumab in Patients With mCRC(FLOWER) | active not recruiting | — | 300 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 27, 2026 | clinicaltrials |
Data updated 23 days agoSource updated May 22, 2026source: clinicaltrials