Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01395667 | Preoperative Chemoradiotherapy Utilizing Intensity Modulated Radiation Therapy in Combination With Bevacizumab-FOLFOX | completed | Phase 1 | 15 | National Taiwan University HospitalOTHER | 1 | Nov 10, 2016 | clinicaltrials |
| NCT00671372 | A Study of Dulanermin Administered in Combination With Camptosar®/Erbitux® Chemotherapy or FOLFIRI (With or Without Bevacizumab) in Subjects With Previously Treated Metastatic Colorectal Cancer | completed | Phase 1 | 42 | Genentech, Inc.INDUSTRY | 1 | Nov 2, 2016 |
| clinicaltrials |
| NCT01148758 | A Dose-finding Study of RO5323441 in Patients With Metastatic Treatment-Refractory Colorectal or Ovarian Cancer | completed | Phase 1 | 7 | Hoffmann-La RocheINDUSTRY | 3 | Nov 2, 2016 | clinicaltrials |
| NCT01085331 | MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC) | terminated | Phase 1 / Phase 2 | 16 | EMD SeronoINDUSTRY | 3 | Oct 19, 2016 | clinicaltrials |
| NCT01522820 | Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors | completed | Phase 1 | 18 | Roswell Park Cancer InstituteOTHER | 1 | Oct 4, 2016 | clinicaltrials |
| NCT02033551 | A Study Evaluating Veliparib as a Single Agent or in Combination With Chemotherapy in Subjects With Solid Tumors | completed | Phase 1 | 47 | AbbVieINDUSTRY | 3 | Sep 27, 2016 | clinicaltrials |
| NCT01376453 | Pre-operative 5-Fluorouracil (5-FU) and Sorafenib With External Radiation in Locally Advanced Rectal Cancer | completed | Phase 1 | 18 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Sep 12, 2016 | clinicaltrials |
| NCT01451632 | A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers | completed | Phase 1 | 48 | Merrimack PharmaceuticalsINDUSTRY | 1 | Sep 8, 2016 | clinicaltrials |
| NCT02886897 | A Study of Combinations of D-CIK Immunotherapy And Anti-PD-1 In Refractory Solid Tumors | unknown | Phase 1 / Phase 2 | 50 | Sun Yat-sen UniversityOTHER | 1 | Sep 1, 2016 | clinicaltrials |
| NCT02882659 | Dendritic Killer Cell-based Immunotherapy for Solid Tumors | unknown | Phase 1 | 18 | FullHope Biomedical Co., Ltd.INDUSTRY | 0 | Aug 30, 2016 | clinicaltrials |
| NCT00496509 | Phase I Efficacy On Vascular Permeability In Patients With Advanced Colorectal Cancer | completed | Phase 1 | 24 | Genzyme, a Sanofi CompanyINDUSTRY | 1 | Aug 26, 2016 | clinicaltrials |
| NCT00499850 | Phase I FOLFOX Combination | completed | Phase 1 | 18 | Genzyme, a Sanofi CompanyINDUSTRY | 1 | Aug 25, 2016 | clinicaltrials |
| NCT01937715 | A Study Of PF-05212384 Plus FOLFIRI Versus Bevacizumab Plus FOLFIRI In Metastatic Colorectal Cancer | terminated | Phase 1 / Phase 2 | 18 | PfizerINDUSTRY | 3 | Aug 18, 2016 | clinicaltrials |
| NCT00588640 | Study of D-Methadone in Patients With Chronic Pain | completed | Phase 1 / Phase 2 | 10 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Aug 10, 2016 | clinicaltrials |
| NCT01111292 | Inositol in Preventing Colorectal Cancer in Patients With Colitis-Associated Dysplasia | terminated | Phase 1 / Phase 2 | 5 | National Cancer Institute (NCI)NIH | 1 | Jul 12, 2016 | clinicaltrials |
| NCT02352571 | Safety Study of GC1118 (Recombinant Human Anti-EGFR Antibody) in Patients With Advanced Solid Cancer | unknown | Phase 1 | 72 | Green Cross CorporationINDUSTRY | 1 | Jul 6, 2016 | clinicaltrials |
| NCT01086267 | Safety and Efficacy Study of BMS-908662 Alone or in Combination With Cetuximab in Subjects With K-RAS or B-RAF Mutation Positive Advanced or Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 17 | Bristol-Myers SquibbINDUSTRY | 2 | Jun 27, 2016 | clinicaltrials |
| NCT00673322 | Trial of Second Generation Designer T Cells in Colorectal Carcinoma | terminated | Phase 1 | 1 | Roger Williams Medical CenterOTHER | 1 | Jun 17, 2016 | clinicaltrials |
| NCT02781155 | Limiting Chemotherapy Side Effects by Using Moxa | unknown | Phase 1 / Phase 2 | 25 | East and North Hertfordshire NHS TrustOTHER_GOV | 1 | May 24, 2016 | clinicaltrials |
| NCT02575508 | Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer | withdrawn | Phase 1 / Phase 2 | 0 | Roswell Park Cancer InstituteOTHER | 1 | May 20, 2016 | clinicaltrials |
| NCT01115790 | A Phase 1 Study in Participants With Advanced Cancer | completed | Phase 1 | 150 | Eli Lilly and CompanyINDUSTRY | 1 | May 10, 2016 | clinicaltrials |
| NCT01675128 | ISIS 183750 With Irinotecan for Advanced Solid Tumors or Colorectal Cancer | completed | Phase 1 / Phase 2 | 24 | National Cancer Institute (NCI)NIH | 1 | Apr 25, 2016 | clinicaltrials |
| NCT02453464 | A Phase Ib Study of Humanized Anti-VEGF Monoclonal Antibody (Sevacizumab) Injection Plus FOLFIRI in Chinese Patients With Metastatic Colorectal Cancer | unknown | Phase 1 | 36 | Jiangsu Simcere Pharmaceutical Co., Ltd.INDUSTRY | 1 | Apr 20, 2016 | clinicaltrials |
| NCT00563316 | Effect of Panitumumab on the Pharmacokinetics of Irinotecan | completed | Phase 1 | 28 | AmgenINDUSTRY | 2 | Apr 12, 2016 | clinicaltrials |
| NCT00185081 | Imaging Colo-rectal Cancer Using a Two Step Antibody Technique in Nuclear Imaging | completed | Phase 1 | 42 | Radboud University Medical CenterOTHER | 1 | Apr 7, 2016 | clinicaltrials |
| NCT00558051 | Alpha-type-1 Dendritic Cell-based Vaccines in Patients With Metastatic Colorectal Cancer | completed | Phase 1 | 15 | Pawel KalinskiOTHER | 1 | Apr 1, 2016 | clinicaltrials |
| NCT01008475 | EMD 525797 in Combination With Cetuximab and Irinotecan in K-ras Wild Type Metastatic Colorectal Cancer(POSEIDON) | completed | Phase 1 / Phase 2 | 232 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 12 | Mar 30, 2016 | clinicaltrials |
| NCT02720926 | Study of TKI 258 in Combination With Xeloda and Oxaliplatin in Advanced Colorectal and Gastric Cancer | terminated | Phase 1 | 3 | National Cancer Centre, SingaporeOTHER | 1 | Mar 28, 2016 | clinicaltrials |
| NCT01626963 | Single-port Versus Conventional Laparoscopic Colorectal Surgery | unknown | Phase 1 / Phase 2 | 50 | North Tees and Hartlepool NHS Foundation TrustOTHER | 1 | Mar 24, 2016 | clinicaltrials |
| NCT00353262 | A Study of Xeloda (Capecitabine) in Combination With Oxaliplatin in Patients With Metastatic Colorectal Cancer. | completed | Phase 1 | 36 | Hoffmann-La RocheINDUSTRY | 1 | Mar 4, 2016 | clinicaltrials |
| NCT01554969 | Phase I Trial of Ganetespib, Capecitabine, and Radiation in Rectal Cancer | completed | Phase 1 | 16 | Emory UniversityOTHER | 1 | Feb 22, 2016 | clinicaltrials |
| NCT00920868 | XAD - Xelox (Capecitabine + Oxaliplatin) + Bevacizumab + Dasatinib(XAD) | completed | Phase 1 | 22 | Herbert Hurwitz, MDOTHER | 1 | Feb 3, 2016 | clinicaltrials |
| NCT01203969 | Safety and Efficacy of Single Port Laparoscopic Surgery in Colon Cancer | completed | Phase 1 | 62 | Kyunghee University Medical CenterOTHER | 1 | Feb 3, 2016 | clinicaltrials |
| NCT02020291 | Phase I Study to Evaluate Safety, Tolerability, Anti-Tumour Activity and PK Profiles of Foxy-5 in Metastatic Breast, Colon or Prostate Cancer | completed | Phase 1 | 31 | WntResearch ABINDUSTRY | 1 | Feb 2, 2016 | clinicaltrials |
| NCT00876954 | Preoperative Hyperthermia in Major Abdominal Surgery Patients | completed | Phase 1 / Phase 2 | 20 | Medical University of ViennaOTHER | 1 | Jan 21, 2016 | clinicaltrials |
| NCT01791309 | Vemurafenib and Panitumumab Combination Therapy in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer | completed | Phase 1 | 16 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 5, 2016 | clinicaltrials |
| NCT02489916 | Donafenib Monotherapy for Previously Treated Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 47 | Suzhou Zelgen Biopharmaceuticals Co.,LtdINDUSTRY | 1 | Jan 5, 2016 | clinicaltrials |
| NCT00574977 | Safety Study of Modified Vaccinia Virus to Cancer | completed | Phase 1 | 26 | David BartlettOTHER | 1 | Dec 28, 2015 | clinicaltrials |
| NCT00581815 | Spectroscopy With Surface Coils and Decoupling | completed | Phase 1 | 582 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 28, 2015 | clinicaltrials |
| NCT01816659 | An Open-Labeled Pilot Study of Biomarker Response Following Short-Term Exposure to Metformin | terminated | Phase 1 | 3 | M.D. Anderson Cancer CenterOTHER | 1 | Nov 18, 2015 | clinicaltrials |
| NCT00594984 | Phase I/II Combination With Irinotecan- Erbitux | completed | Phase 1 / Phase 2 | 38 | Bristol-Myers SquibbINDUSTRY | 7 | Nov 4, 2015 | clinicaltrials |
| NCT00207155 | An Exploratory Pharmacogenomic Study of Monotherapy Erbitux in Subjects With Metastic Colorectal Cancer | completed | Phase 1 | 110 | Eli Lilly and CompanyINDUSTRY | 3 | Oct 28, 2015 | clinicaltrials |
| NCT01516489 | Improving Fecal Occult Blood Test Completion Rates Among Veterans | completed | Phase 1 / Phase 2 | 1,549 | Corporal Michael J. Crescenz VA Medical CenterFED | 1 | Oct 26, 2015 | clinicaltrials |
| NCT02575859 | Adjuvant HIPEC to Prevent Colorectal Peritoneal Metastases in High-risk Patients | completed | Phase 1 / Phase 2 | 20 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 0 | Oct 15, 2015 | clinicaltrials |
| NCT01164215 | Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy | completed | Phase 1 | 76 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Oct 9, 2015 | clinicaltrials |
| NCT01882946 | Safety and Efficacy Study of DCVax-Direct in Solid Tumors | unknown | Phase 1 / Phase 2 | 60 | Northwest BiotherapeuticsINDUSTRY | 1 | Oct 7, 2015 | clinicaltrials |
| NCT00397384 | Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer | completed | Phase 1 | 43 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2015 | clinicaltrials |
| NCT02137356 | Selinexor Combined With Standard Chemoradiation as Neoadjuvant Treatment in Locally Advanced Rectal Cancer | unknown | Phase 1 | 28 | Sheba Medical CenterOTHER_GOV | 1 | Sep 3, 2015 | clinicaltrials |
| NCT00244348 | Hepatic Artery Infusion With Oxaliplatin | withdrawn | Phase 1 / Phase 2 | 0 | Medical College of WisconsinOTHER | 1 | Aug 27, 2015 | clinicaltrials |
Data updated 23 days agoSource updated Nov 10, 2016source: clinicaltrials