Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05659290 | Alternating Treatment With Fruquintinib and Bevacizumab Plus Capecitabine as Maintenance Therapy After First-Line Treatment in Metastatic Colorectal Cancer | unknown | Phase 2 | 40 | Nanfang Hospital, Southern Medical UniversityOTHER | 1 | Jan 6, 2023 | clinicaltrials |
| NCT05664607 | Sarcopenia and Multimodal Rehabilitation on the Prognosis of Rectal Cancer Patients Receiving CCRT | unknown | N/A | 100 | Chang Gung Memorial HospitalOTHER | 1 | Dec 29, 2022 |
| clinicaltrials |
| NCT03088150 | COLLISION Trial - Colorectal Liver Metastases: Surgery vs Thermal Ablation(COLLISION) | unknown | N/A | 618 | Amsterdam UMC, location VUmcOTHER | 1 | Dec 20, 2022 | clinicaltrials |
| NCT05651971 | The Anatomical Localization of the Inferior Mesenteric Artery in Relation to the Left Colonic Artery | unknown | — | 120 | Tang-Du HospitalOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT05645094 | Neoadjuvant Envafolimab in Resectable and Locally Advanced MSI-H/dMMR Rectal Cancer | unknown | — | 38 | Fudan UniversityOTHER | 0 | Dec 13, 2022 | clinicaltrials |
| NCT03883802 | Foxy-5 as Neo-Adjuvant Therapy in Subjects With Wnt-5a Low Colon Cancer(NeoFox) | unknown | Phase 2 | 100 | WntResearch ABINDUSTRY | 1 | Dec 9, 2022 | clinicaltrials |
| NCT05643989 | Self-expandable Metal Stent (SEMS) Endoscopic Placement for Malignant Colonic Obstruction Therapy(PATENCY) | unknown | N/A | 56 | Russian Society of Colorectal SurgeonsOTHER | 1 | Dec 9, 2022 | clinicaltrials |
| NCT05640726 | The First-line Treatment of RCLM With RAS Mutation Was Local Short-course Radiotherapy (SCRT) + PD-1+ Standard Therapy | unknown | Phase 2 | 30 | Fujian Cancer HospitalOTHER_GOV | 0 | Dec 7, 2022 | clinicaltrials |
| NCT05638243 | Evaluation of a Model for the Early Diagnosis of Colorectal Cancer by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA to the Community Colorectal Cancer Screening Program(METHOD-3) | unknown | — | 10,000 | Fudan UniversityOTHER | 1 | Dec 6, 2022 | clinicaltrials |
| NCT05634590 | The Efficacy and Safety of Fruquintinib Plus FOLFIRI/FOLFOX as Second-line Treatment in Patients With RAS-mutant Metastatic Colorectal Cancer | unknown | Phase 2 | 68 | Fudan UniversityOTHER | 1 | Dec 2, 2022 | clinicaltrials |
| NCT05635149 | Predictive Factors for Outcomes of Fruquintinib Plus Immunotherapy in Colorectal Cancer | unknown | — | 100 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Dec 2, 2022 | clinicaltrials |
| NCT05635630 | Predictive Value of ctDNA for NED Status in mCRC and Its Utility in Guiding Therapeutic Intervention | unknown | N/A | 110 | Fudan UniversityOTHER | 1 | Dec 2, 2022 | clinicaltrials |
| NCT04991090 | Management of LLN Metastasis in Locally Advanced Rectal Cancer: A Prospective Radiation Dose Escalation Study | unknown | N/A | 78 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Nov 23, 2022 | clinicaltrials |
| NCT05359406 | A Combination Therapy Including Anti-PD-1 Immunotherapy in Rectal Cancer With Refractory Distal Metastasis(Miracle-2) | unknown | Phase 2 | 51 | LI XIN-XIANGOTHER | 1 | Nov 15, 2022 | clinicaltrials |
| NCT05279612 | Effect Analysis of Neoadjuvant Chemoradiotherapy Combined With Surgery in Laparoscope for Advanced Colon Cancer | unknown | — | 177 | Tang-Du HospitalOTHER | 1 | Nov 14, 2022 | clinicaltrials |
| NCT05372198 | Surufatinib With or Wothout Immunotherapy for Advanced Colorectal Cancer in Later Line | unknown | Phase 2 | 50 | Hubei Cancer HospitalOTHER | 1 | Nov 9, 2022 | clinicaltrials |
| NCT00986661 | A Study to Assess PV-10 Chemoablation of Cancer of the Liver | unknown | Phase 1 | 78 | Provectus Biopharmaceuticals, Inc.INDUSTRY | 1 | Nov 2, 2022 | clinicaltrials |
| NCT04358328 | Effect of CGA for Frail Elderly Patients Operated for Colorectal Cancer - The CRC Frailty-study | unknown | N/A | 340 | Sahlgrenska University HospitalOTHER | 1 | Nov 1, 2022 | clinicaltrials |
| NCT05336643 | Radioisotope and Fluorescence Guidance in Rectal Cancer | unknown | N/A | 10 | University College, LondonOTHER | 1 | Nov 1, 2022 | clinicaltrials |
| NCT05601388 | Role of IMP3 Expression in Colorectal Carcinoma: An Immunohistochemical Study | unknown | — | 60 | Sohag UniversityOTHER | 1 | Nov 1, 2022 | clinicaltrials |
| NCT05446558 | Long-term Results in Intracorporeal Versus Extracorporeal Anastomosis in Laparoscopic Right Colectomy | unknown | N/A | 140 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauOTHER | 1 | Oct 31, 2022 | clinicaltrials |
| NCT04278274 | Post-Neoadjuvant Treatment MRI Based AI System to Predict pCR for Rectal Cancer(MR-AI-pCR) | unknown | — | 205 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Oct 26, 2022 | clinicaltrials |
| NCT05034692 | Application of Overlap Method to Digestive Tract Reconstruction of Totally Laparoscopic Left Colectomy | unknown | N/A | 60 | Tang-Du HospitalOTHER | 1 | Oct 24, 2022 | clinicaltrials |
| NCT05587452 | Early Screening of Colorectal Cancer Based on Plasma Multi-omics Combining With Artificial Intelligence(RECOMMEND) | unknown | — | 950 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Oct 24, 2022 | clinicaltrials |
| NCT05493683 | Disitamab Vedotin Combined With Tislelizumab in Advanced HER2 Positive Colorectal Cancer | unknown | Phase 2 | 29 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Oct 21, 2022 | clinicaltrials |
| NCT05587088 | Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)(PA001) | unknown | Phase 1 / Phase 2 | 82 | Hospital Universitario San IgnacioOTHER | 1 | Oct 19, 2022 | clinicaltrials |
| NCT02633098 | A Safety and Effectiveness Study of Pre-operative Artesunate in Stage II/III Colorectal Cancer(NeoART) | unknown | Phase 2 | 200 | St George's, University of LondonOTHER | 1 | Oct 12, 2022 | clinicaltrials |
| NCT05575635 | Neoadjuvant Treatment of Fruquintinib Combined With Concurrent Chemoradiotherapy for LARC | unknown | Phase 2 | 40 | Henan Provincial People's HospitalOTHER | 0 | Oct 12, 2022 | clinicaltrials |
| NCT04331535 | The Genomic Medicine at VA Study(GenoVA) | unknown | N/A | 1,076 | Boston VA Research Institute, Inc.OTHER | 1 | Oct 3, 2022 | clinicaltrials |
| NCT03868228 | PIPAC for the Treatment of Colorectal Peritoneal Metastases | unknown | Phase 1 / Phase 2 | 30 | Imperial College LondonOTHER | 1 | Sep 28, 2022 | clinicaltrials |
| NCT05551247 | Envafolimab Combined With Endostatin in Recurrent or Metastatic MSS-type Colorectal Cancer | unknown | Phase 2 | 30 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 0 | Sep 22, 2022 | clinicaltrials |
| NCT04801095 | A Phase I Study of WM-S1-030 in Patients With Advanced Solid Tumors | unknown | Phase 1 | 100 | Wellmarker BioINDUSTRY | 2 | Sep 16, 2022 | clinicaltrials |
| NCT05540951 | VIC Regimen Versus Bevacizumab Plus Chemotherapy as First-Line Treatment for BRAF V600E-Mutated Advanced Colorectal Cancer | unknown | Phase 3 | 78 | Fudan UniversityOTHER | 1 | Sep 15, 2022 | clinicaltrials |
| NCT05155124 | Safety of Cetuximab and Trifluridin Tipiracil as the Third-line Therapy in the RASwt mCRC | unknown | Phase 1 | 6 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Sep 13, 2022 | clinicaltrials |
| NCT05530746 | Study on the Diagnostic Value of Multi-omics Combined Detection for Precancerous Lesions of CRC | unknown | — | 500 | Changhai HospitalOTHER | 1 | Sep 7, 2022 | clinicaltrials |
| NCT04874259 | LT for Unresectable Colorectal Liver Metastasis | unknown | N/A | 20 | Seoul National University HospitalOTHER | 1 | Sep 6, 2022 | clinicaltrials |
| NCT05031975 | Temozolomide and Irinotecan in Patients With MGMT Silenced Colorectal Cancer After Adjuvant Chemotherapy(ERASE-TMZ) | unknown | Phase 2 | 35 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Sep 2, 2022 | clinicaltrials |
| NCT04398446 | Effect of Hemp-CBD on Patients With CIPN(Coala-T-CBD) | unknown | Phase 2 | 56 | Main Line HealthOTHER | 1 | Sep 1, 2022 | clinicaltrials |
| NCT05524155 | Sintilimab Combined With Regorafenib and HAIC in Patients With Colorectal Liver Metastasis | unknown | Phase 2 | 30 | Tianjin Medical University Cancer Institute and HospitalOTHER | 0 | Sep 1, 2022 | clinicaltrials |
| NCT05517343 | Impact of Real-time Notification of Colonoscopic Optical Diagnosis on Patients' Anxiety and Depression After Polypectomy | unknown | N/A | 500 | Fu Jen Catholic UniversityOTHER | 1 | Aug 26, 2022 | clinicaltrials |
| NCT04801355 | Full-thickness Laparo-endoscopic Excision vs Laparoscopic Colectomy for Colonic Tumors(FlexLaC) | unknown | N/A | 100 | State Scientific Centre of Coloproctology, Russian FederationOTHER_GOV | 1 | Aug 25, 2022 | clinicaltrials |
| NCT05027737 | Early Ileostomy Closure for Rectal Cancer Patients in North America | unknown | N/A | 118 | Jewish General HospitalOTHER | 1 | Aug 23, 2022 | clinicaltrials |
| NCT05279677 | FMT Combined With Immune Checkpoint Inhibitor and TKI in the Treatment of CRC Patients With Advanced Stage | unknown | Phase 2 | 30 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 23, 2022 | clinicaltrials |
| NCT05314101 | TAS-102 Combined With Bevacizumab and Tislelizumab Third-line or Above in the Treatment of Liver Metastasis in Colorectal Cancer | unknown | Phase 2 | 25 | Fujian Cancer HospitalOTHER_GOV | 1 | Aug 23, 2022 | clinicaltrials |
| NCT05511051 | A Prospective Multi-centered Randomized Controlled Trial on Fruquintinib in Combination With HAIC in the Treatment of Liver Metastatic Colorectal Cancer After Failure of Second-line Systematic Therapy | unknown | Phase 2 | 102 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Aug 22, 2022 | clinicaltrials |
| NCT04966819 | Rectal Cancer Shared Care | unknown | N/A | 80 | Jewish General HospitalOTHER | 1 | Aug 19, 2022 | clinicaltrials |
| NCT04866108 | A Phase II Study of Fruquintinib Combined With Capecitabine as First-line Treatment for Advanced Metastatic Colorectal Cancer Unsuitable for Intravenous Chemotherapy | unknown | Phase 2 | 49 | Beijing Friendship HospitalOTHER | 1 | Aug 18, 2022 | clinicaltrials |
| NCT05004831 | Fruquintinib Combined With TAS-102 in the Treatment of Patients With Advanced Metastatic CRC | unknown | Phase 2 | 54 | Sun Yat-sen UniversityOTHER | 1 | Aug 18, 2022 | clinicaltrials |
| NCT05016869 | Fruquintinib Plus Capecitabine as Maintenance Treatment of RAS / BRAF Wild-type Metastatic Colorectal Cancer | unknown | Phase 1 / Phase 2 | 48 | Chinese Academy of Medical SciencesOTHER | 1 | Aug 18, 2022 | clinicaltrials |
Data updated 24 days agoSource updated Jan 6, 2023source: clinicaltrials