Subtype
Large Intestinal Neoplasm
CI-CAN-00001062Explore in graph →
Non-malignant1,847 active trials21 approved drugs383 evidence items
- NCIt
- C215201
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Subtype
CI-CAN-00001062Explore in graph →
Clinical trials
8,849 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00845039 | A Study of Irinotecan and Cetuximab With or Without IMC-A12 for Treatment of Participants With Colon or Rectum Cancer Who Got Worse After Their First Treatment With Oxaliplatin and Bevacizumab(FC-4) | terminated | Phase 2 | 4 | Eli Lilly and CompanyINDUSTRY | 1 | Jul 2, 2018 | clinicaltrials |
| NCT01197664 | Paricalcitol, Fluorouracil, and Radiation Therapy in Treating Patients With Rectal Cancer That Can Be Removed in Surgery | terminated | Phase 1 | 2 | Wake Forest University Health SciencesOTHER |
| 1 |
| Jul 2, 2018 |
| clinicaltrials |
| NCT02423954 | Study of Nivolumab Plus Chemotherapy in Patients With Advanced Cancer (NivoPlus)(NivoPlus) | terminated | Phase 1 / Phase 2 | 33 | Western Regional Medical CenterOTHER | 1 | Jul 2, 2018 | clinicaltrials |
| NCT00827580 | Eniluracil Hand Foot Syndrome | terminated | Phase 1 | 3 | West Virginia UniversityOTHER | 1 | May 30, 2018 | clinicaltrials |
| NCT00077233 | FOLFIRI or FOLFOX With or Without Cetuximab in Patients With Metastatic Adenocarcinoma of the Colon or Rectum | terminated | Phase 3 | 238 | Alliance for Clinical Trials in OncologyOTHER | 1 | May 16, 2018 | clinicaltrials |
| NCT01887509 | Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology(TRaMA) | terminated | N/A | 21 | IHU StrasbourgOTHER | 1 | May 15, 2018 | clinicaltrials |
| NCT01926769 | A Phase II Study to Determine the Safety and Efficacy of Second-line Treatment With Metformin and Chemotherapy (FOLFOX6 or FOFIRI) in the Second Line Threatment of Advanced Colorectal Cancer | terminated | Phase 2 | 2 | Gachon University Gil Medical CenterOTHER | 1 | May 15, 2018 | clinicaltrials |
| NCT03253185 | A Study of SC-007 in Subjects With Advanced Cancer | terminated | Phase 1 | 7 | AbbVieINDUSTRY | 1 | Apr 27, 2018 | clinicaltrials |
| NCT00910494 | Intraoperative Radiotherapy for Rectal Cancer Using the Photon Radiosurgery System | terminated | N/A | 9 | University of DundeeOTHER | 1 | Apr 24, 2018 | clinicaltrials |
| NCT00663819 | Bioabsorbable Staple Line Reinforcement in Colorectal,Coloanal and Ileoanal Anastomoses | terminated | N/A | 258 | W.L.Gore & AssociatesINDUSTRY | 1 | Apr 17, 2018 | clinicaltrials |
| NCT02577588 | Trial of Adoptive T Cell Therapy With Activated P53 Specific T Cells for Treatment of Advanced Colorectal Cancer(ATACC) | terminated | Phase 1 | 1 | National Center for Tumor Diseases, HeidelbergOTHER | 1 | Apr 11, 2018 | clinicaltrials |
| NCT02503631 | Stool Sample Collection Protocol for Development of Screening Test for Colorectal Cancer and Other Digestive Tract Cancers | terminated | — | 397 | Exact Sciences CorporationINDUSTRY | 2 | Apr 6, 2018 | clinicaltrials |
| NCT02638909 | Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignancies | terminated | Phase 2 | 4 | Criterium, Inc.INDUSTRY | 1 | Apr 2, 2018 | clinicaltrials |
| NCT01284504 | Effect of Celecoxib on Perioperative Inflammatory Response in Colon Cancer | terminated | N/A | 1 | Stanford UniversityOTHER | 1 | Mar 16, 2018 | clinicaltrials |
| NCT00832299 | Neo-Adjuvant FOLFOX for Rectal Carcinoma | terminated | Phase 2 | 2 | Beth Israel Medical CenterOTHER | 1 | Mar 1, 2018 | clinicaltrials |
| NCT02110953 | Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver | terminated | Phase 1 | 2 | Fox Chase Cancer CenterOTHER | 1 | Feb 26, 2018 | clinicaltrials |
| NCT02119676 | Study of Ruxolitinib in Colorectal Cancer Patients | terminated | Phase 2 | 396 | Incyte CorporationINDUSTRY | 8 | Feb 13, 2018 | clinicaltrials |
| NCT01934179 | Telomere Length in Predicting Toxicity in Older Patients With Stage III-IV Colorectal Cancer Undergoing Chemotherapy | terminated | — | 6 | Fox Chase Cancer CenterOTHER | 1 | Feb 7, 2018 | clinicaltrials |
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT02399631 | Enhanced Recovery Program After Laparoscopic Colon Cancer Surgery | terminated | N/A | 180 | Kyungpook National University HospitalOTHER | 1 | Jan 25, 2018 | clinicaltrials |
| NCT02407561 | Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein Expression Assays | terminated | — | 3 | Castle Biosciences IncorporatedINDUSTRY | 1 | Jan 25, 2018 | clinicaltrials |
| NCT01729923 | A Trial of Maintenance ADAPT Therapy With Capecitabine and Celecoxib in Patients With Metastatic Colorectal Cancer(ADAPT) | terminated | Phase 2 | 27 | University of WashingtonOTHER | 1 | Jan 16, 2018 | clinicaltrials |
| NCT01012362 | Study of Pazopanib and Ixabepilone in Patients With Solid Tumors | terminated | Phase 1 | 31 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Dec 28, 2017 | clinicaltrials |
| NCT02182466 | German Colon Capsule Registry(DEKOR) | terminated | — | 120 | Johann Wolfgang Goethe University HospitalOTHER | 1 | Dec 15, 2017 | clinicaltrials |
| NCT00226941 | A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer | terminated | Phase 1 / Phase 2 | 23 | George Albert FisherOTHER | 1 | Dec 8, 2017 | clinicaltrials |
| NCT01279681 | Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer | terminated | Phase 3 | 32 | Alliance for Clinical Trials in OncologyOTHER | 0 | Dec 8, 2017 | clinicaltrials |
| NCT02057991 | Mindfulness-Based Exercise Video in Educating Hispanic/Latino Patients With Colorectal Cancer and Their Caregivers | terminated | N/A | 94 | University of Southern CaliforniaOTHER | 1 | Nov 29, 2017 | clinicaltrials |
| NCT02473094 | Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer(NEOMETRE) | terminated | Phase 2 | 3 | University of Campinas, BrazilOTHER | 1 | Nov 28, 2017 | clinicaltrials |
| NCT00903396 | Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer | terminated | Phase 2 | 7 | Alliance for Clinical Trials in OncologyOTHER | 1 | Nov 24, 2017 | clinicaltrials |
| NCT00625183 | Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma | terminated | Phase 2 | 5 | Roswell Park Cancer InstituteOTHER | 1 | Nov 17, 2017 | clinicaltrials |
| NCT01606124 | Polyphenon E in Treating Patients With High-Risk of Colorectal Cancer | terminated | Phase 2 | 39 | Mayo ClinicOTHER | 1 | Oct 27, 2017 | clinicaltrials |
| NCT01939223 | Colorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudy(COAST) | terminated | Phase 3 | 25 | BayerINDUSTRY | 14 | Oct 20, 2017 | clinicaltrials |
| NCT00003485 | Antineoplaston Therapy in Treating Patients With Metastatic or Unresectable Colon Cancer | terminated | Phase 2 | 15 | Burzynski Research InstituteOTHER | 1 | Sep 28, 2017 | clinicaltrials |
| NCT01765582 | Sequential and Concurrent FOLFOXIRI/Bevacizumab Regimens Versus FOLFOX/Bevacizumab in First-Line Metastatic Colorectal Cancer(STEAM) | terminated | Phase 2 | 280 | Hoffmann-La RocheINDUSTRY | 1 | Sep 18, 2017 | clinicaltrials |
| NCT02538627 | Phase 1 Combination Study of MM-151 With MM-121, MM-141, or Trametinib | terminated | Phase 1 | 5 | Merrimack PharmaceuticalsINDUSTRY | 1 | Sep 5, 2017 | clinicaltrials |
| NCT02609451 | Closure of Protective Ileostomy 2 vs. 12 Weeks After TME(Closure2vs12) | terminated | N/A | 71 | Kantonsspital LiestalOTHER | 1 | Aug 31, 2017 | clinicaltrials |
| NCT01114256 | FNA Tumor Sampling for CD137 Modulation: A Pilot Study | terminated | — | 83 | Stanford UniversityOTHER | 1 | Aug 3, 2017 | clinicaltrials |
| NCT02175654 | Regorafenib as Single Agent in Patients With Metastatic Colorectal Cancer (mCRC) With Any RAS or BRAF Mutation Previously Treated With FOLFOXIRI Plus Bevacizumab(PREVIUM) | terminated | Phase 2 | 15 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Aug 1, 2017 | clinicaltrials |
| NCT01847599 | Educational Intervention to Adherence of Patients Treated by Capecitabine +/- Lapatinib(ProMETheX) | terminated | N/A | 65 | Centre Jean PerrinOTHER | 1 | Jul 21, 2017 | clinicaltrials |
| NCT01309126 | Study of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal Cancer(PRIMUS) | terminated | Phase 3 | 217 | HiberCell, Inc.INDUSTRY | 4 | Jul 13, 2017 | clinicaltrials |
| NCT01134666 | An Observational Study to Evaluate the Safety and Efficacy of FOLFIRI / FOLFOX Plus Cetuximab as First-line Therapy in Patients With KRAS Wild-type Metastatic Colorectal Cancer | terminated | — | 165 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Jun 9, 2017 | clinicaltrials |
| NCT00423150 | Phase 2 Study of Temozolomide in Pre-Selected Advanced Aerodigestive Tract Cancers (Study P04273AM2)(TERMINATED) | terminated | Phase 2 | 86 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jun 8, 2017 | clinicaltrials |
| NCT01940237 | A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients With Prostate, Colorectal, Lung and Pancreatic Cancer | terminated | N/A | 4 | New York State Psychiatric InstituteOTHER | 1 | May 19, 2017 | clinicaltrials |
| NCT00449163 | Combination Chemotherapy and Bevacizumab in Treating Patients With Stage IV Colorectal Cancer | terminated | Phase 2 | 25 | University of MiamiOTHER | 1 | May 11, 2017 | clinicaltrials |
| NCT01326065 | Implementation of Laparoscopy-assisted Surgery for Colon Cancer | terminated | — | 60 | Helse Stavanger HFOTHER_GOV | 1 | May 9, 2017 | clinicaltrials |
| NCT02277093 | Pacritinib to Inhibit JAK/STAT Signaling in Refractory Colorectal Cancer | terminated | Phase 2 | 11 | Washington University School of MedicineOTHER | 1 | May 1, 2017 | clinicaltrials |
| NCT02060669 | Xeloda Maintenance Versus BSC in Metastatic Colorectal Cancer | terminated | Phase 3 | 10 | Samsung Medical CenterOTHER | 1 | Apr 27, 2017 | clinicaltrials |
| NCT00126451 | A Clinical Trial of Oral Suberoylanilide Hydroxamic Acid (SAHA) in Patients With Relapsed or Refractory Breast, Colorectal and Non-Small Cell Lung Cancer (0683-011)(TERMINATED) | terminated | Phase 2 | 16 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Apr 10, 2017 | clinicaltrials |
| NCT00588900 | Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab | terminated | Phase 2 | 5 | Alliance for Clinical Trials in OncologyOTHER | 1 | Apr 5, 2017 | clinicaltrials |
Data updated 23 days agoSource updated Jul 2, 2018source: clinicaltrials