Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology

Inclusion Criteria:

* Patient, male or female over 18 years old
* Patient with rectal adenocarcinoma :

  * stage T1 or T2, N0 (one single evaluation, during resection)
  * stage N+ or T3 (pre- and post-radiochemotherapy evaluations)
* Absence of contra-indication to rectoscopy conduct
* Patient able to understand the study and to provide written informed consent
* Patient registered with the French social security regime

Non-inclusion criteria:

* Absence of written informed consent
* Patient with known or suspected allergy to fluorescein
* Patient with history of reaction jeopardizing the vital prognosis during angiography
* Patient with history of multiple or serious allergic reaction to drugs
* Patient presenting, in the investigator's judgment, a condition or disease preventing their participation to study procedures
* Patient pregnant or breast-feeding
* Patient within exclusion period from other clinical trial
* Patient having forfeited their freedom of an administrative or legal obligation
* Patient being under guardianship