Cancer Family
Intestinal Neoplasm
CI-CAN-00000209Explore in graph →
Non-malignant1,892 active trials21 approved drugs383 evidence items
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Cancer Family
CI-CAN-00000209Explore in graph →
Clinical trials
9,155 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05212012 | D,L-MEthadone and mFOLFOX6 in Treatment of Advanced Colorectal Cancer(MEFOX) | active not recruiting | Phase 1 / Phase 2 | 11 | AIO-Studien-gGmbHOTHER | 1 | Oct 3, 2025 | clinicaltrials |
| NCT06784947 | Trial of Atezolizumab, Bevacizumab, and Tiragolumab in Patients With Microsatellite Stable, Metastatic Colorectal Cancer | active not recruiting | Phase 2 | 13 | University of Colorado, DenverOTHER | 1 | Oct 2, 2025 |
| clinicaltrials |
| NCT02505750 | Safety of a Boost (CXB or EBRT) in Combination With Neoadjuvant Chemoradiotherapy for Early Rectal Adenocarcinoma(OPERA) | active not recruiting | Phase 3 | 148 | Centre Antoine LacassagneOTHER | 3 | Sep 29, 2025 | clinicaltrials |
| NCT05163028 | A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations | active not recruiting | Phase 1 | 42 | HUYABIO International, LLC.INDUSTRY | 2 | Sep 24, 2025 | clinicaltrials |
| NCT05485974 | A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation | active not recruiting | Phase 1 | 44 | HUYABIO International, LLC.INDUSTRY | 2 | Sep 24, 2025 | clinicaltrials |
| NCT06124378 | Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer | active not recruiting | Phase 2 | 60 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Sep 24, 2025 | clinicaltrials |
| NCT02628067 | Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) | active not recruiting | Phase 2 | 1,609 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 22, 2025 | clinicaltrials |
| NCT03975491 | The Exercise And Colorectal Cancer Treatment Trial(EXACT) | active not recruiting | N/A | 60 | Pennington Biomedical Research CenterOTHER | 1 | Sep 22, 2025 | clinicaltrials |
| NCT04763915 | Improving Care After Inherited Cancer Testing(IMPACT) | active not recruiting | N/A | 720 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Sep 19, 2025 | clinicaltrials |
| NCT04416490 | Oxaliplatin Adjuvant Chemotherapy After Curative Resection of Primary Colon Cancer(OCEAN) | active not recruiting | — | 2,013 | Boryung Pharmaceutical Co., LtdINDUSTRY | 1 | Sep 12, 2025 | clinicaltrials |
| NCT05990543 | Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer | active not recruiting | Phase 1 / Phase 2 | 59 | Korea University Anam HospitalOTHER | 1 | Sep 8, 2025 | clinicaltrials |
| NCT05693649 | Behavioral Economic Approaches for Population-Based Colorectal Cancer Screening | active not recruiting | N/A | 20,000 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT06959849 | Robot-assisted Surgery for Colorectal Cancer Resection: A Population-based Analysis of Prevalence, Trends and Outcomes(RoChiKoKa) | active not recruiting | — | 128,000 | Medizinische Hochschule Brandenburg Theodor FontaneOTHER | 0 | Sep 5, 2025 | clinicaltrials |
| NCT05608044 | A Study of Botensilimab and Balstilimab for the Treatment of Colorectal Cancer | active not recruiting | Phase 2 | 234 | Agenus Inc.INDUSTRY | 8 | Sep 4, 2025 | clinicaltrials |
| NCT05511688 | National Cohort of Colorectal Cancers With Microsatellite Instability | active not recruiting | — | 637 | Federation Francophone de Cancerologie DigestiveOTHER | 1 | Sep 2, 2025 | clinicaltrials |
| NCT06728358 | The Future Management of Patients With Neoplasms of the Gastro-intestinal Tract(SOCRATE) | active not recruiting | N/A | 300 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Aug 26, 2025 | clinicaltrials |
| NCT07137000 | The Effect of Art Therapy in Patients Undergoing Colorectal Cancer | active not recruiting | N/A | 96 | Saglik Bilimleri UniversitesiOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT04166604 | LONsurf and G-CSF Use: Being On A Right Dose-intensity to Optimize Treatment Efficacy(LONGBOARD) | active not recruiting | Phase 2 | 176 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Aug 19, 2025 | clinicaltrials |
| NCT03170960 | Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors | active not recruiting | Phase 1 | 914 | ExelixisINDUSTRY | 9 | Aug 17, 2025 | clinicaltrials |
| NCT03283540 | Transanal Total Mesorectal Excision for Rectal Cancer on Anal Physiology + Fecal Incontinence | active not recruiting | — | 39 | Case Comprehensive Cancer CenterOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT06087718 | Feasibility of the Maastro Applicator in Rectal Cancer | active not recruiting | N/A | 10 | Maastricht Radiation OncologyOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT05057013 | A Phase I/IIa Trial of HMBD-001 in Advanced HER3 Positive Solid Tumours | active not recruiting | Phase 1 / Phase 2 | 81 | Cancer Research UKOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT07106463 | Microbiota: Its Role in Chronic Inflammation, IDB and Risk of Colorectal Cancer. Evaluation of a Predictive Prognostic Model With Therapeutic Implications | active not recruiting | — | 100 | University of MessinaOTHER | 1 | Aug 6, 2025 | clinicaltrials |
| NCT07104877 | A Study of SYS6010 in Combination With SYH2051 in Patients With Advanced Colorectal Cancer and Other Gastrointestinal Tumors | active not recruiting | N/A | 25 | Fujian Cancer HospitalOTHER_GOV | 1 | Aug 5, 2025 | clinicaltrials |
| NCT03493048 | Cetuximab Plus FOLFOXIRI vs Cetuximab Plus FOLFOX For CRCLM | active not recruiting | Phase 2 | 146 | Sun Yat-sen UniversityOTHER | 1 | Aug 3, 2025 | clinicaltrials |
| NCT03326791 | Aspirin in Colorectal Cancer Liver Metastases(ASAC) | active not recruiting | Phase 2 / Phase 3 | 466 | Oslo University HospitalOTHER | 3 | Jul 31, 2025 | clinicaltrials |
| NCT05444491 | Application of Polygenic Methylation Markers in Postoperative Recurrence Monitoring of Colorectal Cancer | active not recruiting | — | 800 | Singlera Genomics Inc.INDUSTRY | 1 | Jul 31, 2025 | clinicaltrials |
| NCT06866574 | A Phase III Trial to Evaluate the Efficacy, Immunogenicity and Safety of a Recombinant Human Papillomavirus 9-Valent (Types 6, 11, 16, 18, 31, 33, 45, 52, 58) Vaccine (E.Coli) in Chinese Males | active not recruiting | Phase 3 | 9,300 | Xiamen UniversityOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT04852653 | A Prospective Feasibility Study Evaluating Extracellular Vesicles Obtained by Liquid Biopsy for Neoadjuvant Treatment Response Assessment in Rectal Cancer(RECC-EV) | active not recruiting | — | 58 | University Hospital, BordeauxOTHER | 1 | Jul 30, 2025 | clinicaltrials |
| NCT06105021 | Phase I Study of Autologous CD8+ and CD4+ Engineered T Cell Receptor T Cells in Subjects With Advanced or Metastatic Solid Tumor | active not recruiting | Phase 1 / Phase 2 | 100 | Affini-T Therapeutics, Inc.INDUSTRY | 1 | Jul 30, 2025 | clinicaltrials |
| NCT06398743 | First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer(MRD) | active not recruiting | — | 416 | Exact Sciences CorporationINDUSTRY | 5 | Jul 24, 2025 | clinicaltrials |
| NCT03597204 | Effectiveness of Fecal Immunnochemical Test and Colonoscopy Screening in Hong Kong | active not recruiting | N/A | 15,000 | Chinese University of Hong KongOTHER | 1 | Jul 23, 2025 | clinicaltrials |
| NCT03694938 | Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients | active not recruiting | N/A | 143 | Poitiers University HospitalOTHER | 1 | Jul 20, 2025 | clinicaltrials |
| NCT03828227 | QoL in mCRC Elderly Patients Receiving First-line Therapy Based on Simplified Geriatric Parameters.(COLAGE) | active not recruiting | Phase 3 | 49 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jul 18, 2025 | clinicaltrials |
| NCT06199973 | Injection of SHR-A1811 Versus Physician Choiced Treatment in Patients With Advanced Colorectal Cancer Who Had Failed to Respond to Oxaliplatin, 5-fu, and Irinotecan | active not recruiting | Phase 3 | 130 | Suzhou Suncadia Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | Jul 17, 2025 | clinicaltrials |
| NCT07063550 | Microplastics in Paraneoplastic and Intratumoral for Colorectal Cancer | active not recruiting | — | 100 | Dong PengOTHER | 1 | Jul 14, 2025 | clinicaltrials |
| NCT04922853 | Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer(COPEC) | active not recruiting | Phase 3 | 554 | West China HospitalOTHER | 1 | Jul 11, 2025 | clinicaltrials |
| NCT02078804 | Colonoscopy and FIT as Colorectal Cancer Screening Test in the Average Risk Population | active not recruiting | N/A | 278,000 | Uppsala University HospitalOTHER | 0 | Jun 17, 2025 | clinicaltrials |
| NCT04404777 | Local Recurrence Due to Rectal Cancer in Sweden(LERIS) | active not recruiting | — | 12,000 | Sahlgrenska University HospitalOTHER | 1 | Jun 17, 2025 | clinicaltrials |
| NCT05118724 | Atezolizumab in Patients With MSI-h/MMR-D Stage II High Risk and Stage III Colorectal Cancer Ineligible for Oxaliplatin(ANTONIO) | active not recruiting | Phase 2 | 80 | AIO-Studien-gGmbHOTHER | 1 | Jun 15, 2025 | clinicaltrials |
| NCT04730544 | Two Combination Treatment Regimens of Nivolumab and Ipilimumab in Patients With dMMR and / or MSI mCRC.(NIPISAFE) | active not recruiting | Phase 2 | 96 | GERCOR - Multidisciplinary Oncology Cooperative GroupOTHER | 1 | Jun 13, 2025 | clinicaltrials |
| NCT07020468 | Neoadjuvant Therapy （NALIRIFOX） for Locally Advanced Colon and Upper Rectal Cancer(HOPE) | active not recruiting | Phase 4 | 57 | Affiliated Cancer Hospital of Shantou University Medical CollegeOTHER | 1 | Jun 13, 2025 | clinicaltrials |
| NCT02804815 | Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours | active not recruiting | Phase 3 | 11,000 | University College, LondonOTHER | 2 | Jun 10, 2025 | clinicaltrials |
| NCT04017455 | Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN)(TARZAN) | active not recruiting | Phase 2 | 38 | The Netherlands Cancer InstituteOTHER | 1 | Jun 8, 2025 | clinicaltrials |
| NCT05201352 | Evaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine(TASKIN) | active not recruiting | Phase 1 / Phase 2 | 160 | Centre Georges Francois LeclercOTHER | 1 | May 30, 2025 | clinicaltrials |
| NCT05551052 | CRC Detection Reliable Assessment With Blood(CRC-DRAW) | active not recruiting | — | 196 | New Day DiagnosticsNETWORK | 1 | May 29, 2025 | clinicaltrials |
| NCT05704985 | Evaluating Safety and Biomarkers Using DK210 (EGFR) for Locally Advanced or Metastatic EGFR+ Tumors | active not recruiting | Phase 1 | 39 | DEKA BiosciencesINDUSTRY | 1 | May 29, 2025 | clinicaltrials |
| NCT05312398 | CAPRI 2 GOIM Study: Investigate the Efficacy and Safety of a Bio-marker Driven Cetuximab-based Treatment Regimen | active not recruiting | Phase 2 | 219 | University of Campania Luigi VanvitelliOTHER | 1 | May 25, 2025 | clinicaltrials |
| NCT05555862 | Artesunate Suppositories for the Treatment of HIV-negative Patients With Intra-anal HSIL(anal HSIL HIV-) | active not recruiting | Phase 2 | 17 | Frantz Viral Therapeutics, LLCINDUSTRY | 1 | May 18, 2025 | clinicaltrials |
| NCT05141721 | A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer | active not recruiting | Phase 2 / Phase 3 | 700 | Seattle Project CorporationINDUSTRY | 1 | May 16, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Oct 3, 2025source: clinicaltrials