Subtype
Intestinal Carcinoma
CI-CAN-00002922Explore in graph →
409 active trials5 approved drugs22 evidence items
- NCIt
- C227934
Loading cancer entity…
Subtype
CI-CAN-00002922Explore in graph →
Genomics
27 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
224 cases with simple somatic mutation data · 276 cases total · 2026-02-19 · mapped to Colorectal Adenocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | APC |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 168 |
| 224 |
| 75% |
| cbioportal |
| 2 | TP53 | Ssm | 121 | 224 | 54% | cbioportal |
| 3 | KRAS | Ssm | 94 | 224 | 42% | cbioportal |
| 4 | TTN | Ssm | 80 | 224 | 35.7% | cbioportal |
| 5 | SYNE1 | Ssm | 47 | 224 | 21% | cbioportal |
| 6 | PIK3CA | Ssm | 45 | 224 | 20.1% | cbioportal |
| 7 | LRP1B | Ssm | 40 | 224 | 17.9% | cbioportal |
| 8 | FAT4 | Ssm | 39 | 224 | 17.4% | cbioportal |
| 9 | MUC16 | Ssm | 39 | 224 | 17.4% | cbioportal |
| 10 | FBXW7 | Ssm | 37 | 224 | 16.5% | cbioportal |
| 12 | LRP2 | Ssm | 34 | 224 | 15.2% | cbioportal |
| 11 | DNAH5 | Ssm | 34 | 224 | 15.2% | cbioportal |
| 13 | DMD | Ssm | 33 | 224 | 14.7% | cbioportal |
| 14 | FLG | Ssm | 32 | 224 | 14.3% | cbioportal |
| 16 | FAT2 | Ssm | 30 | 224 | 13.4% | cbioportal |
| 15 | ANK2 | Ssm | 30 | 224 | 13.4% | cbioportal |
| 17 | HMCN1 | Ssm | 29 | 224 | 12.9% | cbioportal |
| 21 | RYR2 | Ssm | 28 | 224 | 12.5% | cbioportal |
| 19 | CSMD1 | Ssm | 28 | 224 | 12.5% | cbioportal |
| 18 | COL6A3 | Ssm | 28 | 224 | 12.5% | cbioportal |
| 20 | CSMD3 | Ssm | 28 | 224 | 12.5% | cbioportal |
| 22 | SDK1 | Ssm | 27 | 224 | 12.1% | cbioportal |
| 23 | TCF7L2 | Ssm | 27 | 224 | 12.1% | cbioportal |
| 26 | SMAD4 | Ssm | 26 | 224 | 11.6% | cbioportal |
| 24 | DNAH2 | Ssm | 26 | 224 | 11.6% | cbioportal |
| 27 | USH2A | Ssm | 26 | 224 | 11.6% | cbioportal |
| 25 | PKHD1 | Ssm | 26 | 224 | 11.6% | cbioportal |
| 29 | AMER1 | Ssm | 25 | 224 | 11.2% | cbioportal |
| 28 | ACVR2A | Ssm | 25 | 224 | 11.2% | cbioportal |
| 31 | HYDIN | Ssm | 25 | 224 | 11.2% | cbioportal |
Data updated 22 days agoSource updated 2026-02-19