Skip to content

CancerIndexthe global index of cancer

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Pulse Data updates Year in cancer Taxonomy Countries Compare Trial intelligence Trial map Drug pipeline Sources Methodology About Trust & policies Data downloads Developers (API)

Loading cancer entity…

CancerIndex

CancerIndex is a research and information platform. It is not a physician, does not diagnose, and does not recommend treatment. Population statistics do not predict individual outcomes.

Every number links to its source and retrieval date. Derived metrics carry a formula version. AI-generated synthesis is not enabled in this phase; all content is database-grounded.

About Trust & policies Data explorer Data downloads Pulse Data update log Developers (API)Sources Methodology Taxonomy Countries Compare Contact · contact@spboucher.ai Status

© 2026 CancerIndex · built and maintained by Simon-Pierre Boucher · contact contact@spboucher.ai · hosted on MacLustr (www.maclustr.io). Source data remains under the license of each provider — see /sources.

Head and Neck Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Head and Neck Neoplasm

Cancer Family

Head and Neck Neoplasm

CI-CAN-00000021Explore in graph →

Non-malignant1,571 active trials17 approved drugs142 evidence items

NCIt: C3077
MeSH: D006258

Overview
Statistics
Survival
Genomics28
Variants & evidence142
Drugs54
Trials6372
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (323)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 10, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 301–323 of 323 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin.
· Cancer Res · 2009 · PMID 19706758 · validated civic_curation pubmed
Frequent promoter hypermethylation of PTPRT increases STAT3 activation and sensitivity to STAT3 inhibition in head and neck cancer.
· Oncogene · 2016 · PMID 25982282 · validated civic_curation pubmed
Response of head and neck squamous cell carcinoma cells carrying PIK3CA mutations to selected targeted therapies.
· JAMA Otolaryngol Head Neck Surg · 2015 · PMID 25855885 · validated civic_curation pubmed
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974.
· Proc Natl Acad Sci U S A · 2013 · PMID 24277854 · validated civic_curation pubmed
In vitro anticancer activity of PI3K alpha selective inhibitor BYL719 in head and neck cancer.
· Anticancer Res · 2015 · PMID 25550549 · validated civic_curation pubmed
Martelotto et al. J Pathol 2015
· 2015 · PMID 26095796 · validated cbioportal_study pubmed
Allen et al. J Clin Invest 2019
· 2019 · PMID 31483290 · validated cbioportal_study pubmed

Showing 301–323 of 323 publications

← Previous
1
…
12
13
Next →

Ross et al. Am J Surg Pathl 2014

· 2014 · PMID 24418857 · validated cbioportal_study pubmed

Rettig et al, Cancer Prev Res 2016

· 2016 · PMID 26862087 · validated cbioportal_study pubmed

Mitani et al. Clin Cancer Res 2015

· 2015 · PMID 26631609 · validated cbioportal_study pubmed

Drier et al. Nature Genetics 2016

· 2016 · PMID 26829750 · validated cbioportal_study pubmed

Ho et al. Nat Genet 2013

· 2013 · PMID 23685749 · validated cbioportal_study pubmed

Stephens et al. JCI 2013

· 2013 · PMID 23778141 · validated cbioportal_study pubmed

Aidan et al. Nature 2025

· 2025 · PMID 40097403 · validated cbioportal_study pubmed

Stransky et al. Science 2011

· 2011 · PMID 21798893 · validated cbioportal_study pubmed

Agrawal et al. Science 2011

· 2011 · PMID 21798897 · validated cbioportal_study pubmed

Pickering et al. Cancer Discov 2013

· 2013 · PMID 23619168 · validated cbioportal_study pubmed

TCGA, Nature 2015

· 2015 · PMID 25631445 · validated cbioportal_study pubmed

Lin et al. Nat Genet 2014

· 2014 · PMID 24952746 · validated cbioportal_study pubmed

Jial et al. J Pathol 2014

· 2014 · PMID 24293293 · validated cbioportal_study pubmed

Lin, Andrew L et al, Acta Neuropathologica 2024

· 2024 · PMID 38758238 · validated cbioportal_study pubmed

TCGA, Cell 2014

· 2014 · PMID 25417114 · validated cbioportal_study pubmed

Frameshift events predict anti-PD-1/L1 response in head and neck cancer.

· JCI Insight · 2018 · PMID 29467336 · validated civic_curation pubmed