Cancer
Giant Cell Tumor
CI-CAN-00000187Explore in graph →
Non-malignant17 active trials3 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer
CI-CAN-00000187Explore in graph →
Clinical trials
52 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04703322 | A Study of Pexidartinib in Tenosynovial Giant Cell Tumor in Japan | completed | Phase 2 | 9 | Daiichi Sankyo Co., Ltd.INDUSTRY | 1 | Jun 24, 2026 | clinicaltrials |
| NCT01207492 | Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor | completed | Phase 2 | 17 | Andrew J. Wagner, MD, PhDOTHER | 1 | Feb 20, 2026 | clinicaltrials |
| NCT04526704 | Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) Previously Treated With Pexidartinib(PLX3397) | completed | Phase 4 | 32 | Daiichi SankyoINDUSTRY | 7 | Dec 30, 2024 | clinicaltrials |
| NCT05349643 |
Data updated 22 days agoSource updated Jun 24, 2026source: clinicaltrials
| A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT |
| completed |
| Phase 2 |
| 20 |
| AmMax Bio, Inc.INDUSTRY |
| 3 |
| Jul 5, 2024 |
| clinicaltrials |
| NCT04731675 | An Open-Label Study of Intra-articular AMB-05X Injections in Subjects With Tenosynovial Giant Cell Tumor of the Knee | completed | Phase 2 | 11 | AmMax Bio, Inc.INDUSTRY | 4 | Jun 27, 2024 | clinicaltrials |
| NCT03301857 | Long-term Safety Follow-up of Subjects With Giant Cell Tumor of Bone Treated With Denosumab in Study 20062004 | completed | Phase 4 | 85 | AmgenINDUSTRY | 8 | May 20, 2024 | clinicaltrials |
| NCT06331104 | Network Pharmacology Prediction: Mechanism Study of Puerarin in the Treatment of Giant Cell Tumors of Bone | completed | — | 145 | Changye ZouOTHER | 1 | Apr 2, 2024 | clinicaltrials |
| NCT05542524 | Oral Care of Patients Treated With Anti-RANK-ligand Antibodies for a Giant Cell Tumour(DENO) | completed | — | 12 | University Hospital, Strasbourg, FranceOTHER | 1 | Dec 13, 2023 | clinicaltrials |
| NCT02948088 | Tenosynovial Giant Cell Tumors (TGCT) Observational Platform Project(TOP) | completed | — | 183 | Daiichi SankyoINDUSTRY | 8 | Oct 31, 2023 | clinicaltrials |
| NCT00396279 | Safety and Efficacy Study of Denosumab in Patients With Recurrent or Unresectable Giant Cell Tumor of Bone | completed | Phase 2 | 37 | AmgenINDUSTRY | 0 | Nov 8, 2022 | clinicaltrials |
| NCT04952896 | Clinical Study of Magnetic Resonance Imaging and Deep Learning of Joint Synovial Disease | completed | — | 350 | Peking University Third HospitalOTHER | 1 | Nov 2, 2022 | clinicaltrials |
| NCT00680992 | Study of Denosumab in Subjects With Giant Cell Tumor of Bone | completed | Phase 2 | 535 | AmgenINDUSTRY | 12 | Sep 22, 2022 | clinicaltrials |
| NCT05402865 | A Real-world Study on Patients of Unresectable Giant Cell Tumor of Bone | completed | — | 301 | Shanghai JMT-Bio Inc.INDUSTRY | 1 | Jun 2, 2022 | clinicaltrials |
| NCT02371369 | Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS)(ENLIVEN) | completed | Phase 3 | 120 | Daiichi SankyoINDUSTRY | 12 | May 11, 2022 | clinicaltrials |
| NCT02471716 | Study of Cabiralizumab in Patients With Pigmented Villonodular Synovitis / Diffuse Type Tenosynovial Giant Cell Tumor(FPA008-002) | completed | Phase 1 / Phase 2 | 66 | Five Prime Therapeutics, Inc.INDUSTRY | 6 | Aug 31, 2021 | clinicaltrials |
| NCT04955535 | Screening of Specific Genes for Pigmented Villous Nodular Synovitis | completed | — | 60 | Peking University Third HospitalOTHER | 1 | Jul 8, 2021 | clinicaltrials |
| NCT04002817 | Giant Cell Tumor of the Bone in Young Patients | completed | — | 18 | Istituto Ortopedico RizzoliOTHER | 1 | May 4, 2021 | clinicaltrials |
| NCT01643850 | MCS110 in Patients With Pigmented Villonodular Synovitis (PVNS) | completed | Phase 2 | 36 | Novartis PharmaceuticalsINDUSTRY | 2 | Jan 5, 2021 | clinicaltrials |
| NCT00464620 | Trial of Dasatinib in Advanced Sarcomas | completed | Phase 2 | 366 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Nov 23, 2018 | clinicaltrials |
| NCT02996734 | Giant Cell Tumor of the Extremities Treated With Surgery and/or Medical Treatment(GCTLIMBS) | completed | — | 412 | Istituto Ortopedico RizzoliOTHER | 0 | Dec 22, 2016 | clinicaltrials |
| NCT01261429 | Study of Nilotinib Efficacy in Pigmented Villo-Nodular Synovitis/ Tenosynovial Giant Cell Tumour (PVNS/TGCT) | completed | Phase 2 | 50 | Centre Leon BerardOTHER | 5 | Apr 16, 2013 | clinicaltrials |