Clinical trial · Observational
Screening of Specific Genes for Pigmented Villous Nodular Synovitis
NCT04955535CI-TRIAL-00052589completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This study retrospectively analyzed the history of present illness of PVNS patients in our hospital. The enrolled patients were followed up by telephone to follow up their postoperative recovery and living conditions. Take the patient's pathological specimens for immunohistochemical testing, evaluate the relationship between the expression of different molecular targets, clinical manifestations and patient prognosis, and explore new molecular targets related to disease diagnosis and treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Pigmented Villonodular Synovitis | Tenosynovial Giant Cell Tumor, Diffuse Type | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Arthroscopic synovectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (6)
- measure
- Difference of scale score between immunohistochemistry positive group and negative group
- timeFrame
- One week after surgery
- description
- Difference of Visual Analog Score for pain between CSF-1 immunohistochemistry positive group and negative group
- measure
- Difference of Visual Analog Score for pain between TNF-α immunohistochemistry positive group and negative group
- timeFrame
- One week after surgery
- description
- Difference of Visual Analog Score for pain between TNF-α immunohistochemistry positive group and negative group
- measure
- Difference of Visual Analog Score for pain between IL-1B immunohistochemistry positive group and negative group
- timeFrame
- One week after surgery
- description
- Difference of Visual Analog Score for pain between IL-1B immunohistochemistry positive group and negative group
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 60 Years
Show eligibility criteria text
Inclusion Criteria: 1. Clinical diagnosis of pigmented villonodular synovitis. 2. Clinical diagnosis of giant cell tumor of tendon sheath Exclusion Criteria: 1. No surgical treatment. 2. There were no pathological specimens during the operation. 3. The age of the patient is less than 18 years old or more than 60 years old. 4. The operation record shows nodular type.
References
Publications (0)
Data not yet available
No reference posted for this study.