Cancer Family
Esophageal Neoplasm
CI-CAN-00000174Explore in graph →
Non-malignant555 active trials6 approved drugs12 evidence items
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Cancer Family
CI-CAN-00000174Explore in graph →
Clinical trials
2,208 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06219031 | A Study of the Tumor Microenvironment Affecting the Efficacy of Immunotherapy for Esophageal Cancer | completed | — | 22 | Renmin Hospital of Wuhan UniversityOTHER | 1 | Jan 26, 2024 | clinicaltrials |
| NCT03196232 | Epacadostat and Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Junction or Gastric Cancer | completed | Phase 2 | 3 | George Albert FisherOTHER | 1 | Jan 23, 2024 |
| NCT03543813 | PROCLAIM-CX-2029: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2029 for Patients With Solid Tumors or DLBCL | completed | Phase 1 / Phase 2 | 133 | CytomX TherapeuticsINDUSTRY | 4 | Jan 23, 2024 | clinicaltrials |
| NCT03099382 | Study of SHR-1210 Versus Investigator's Choice of Chemotherapy for Participants With Advanced Esophageal Cancer | completed | Phase 3 | 457 | Jiangsu HengRui Medicine Co., Ltd.INDUSTRY | 1 | Jan 22, 2024 | clinicaltrials |
| NCT04568200 | Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Resectable Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 60 | Peking Union Medical College HospitalOTHER | 1 | Jan 22, 2024 | clinicaltrials |
| NCT03600831 | Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 2 / Phase 3 | 434 | Huai'an First People's HospitalOTHER | 1 | Jan 9, 2024 | clinicaltrials |
| NCT06184841 | HAIC Combined Sintilimab for Liver Metastasis From Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 25 | Peking University Cancer Hospital & InstituteOTHER | 1 | Dec 28, 2023 | clinicaltrials |
| NCT02379039 | Multimodal Monitoring of Radiotherapy Response in Squamous Cell Cancer(MORRIS) | completed | — | 118 | Umeå UniversityOTHER | 1 | Dec 22, 2023 | clinicaltrials |
| NCT02916511 | Study of Extensive Clinical Target Volumes in Postoperative Radiotherapy Concurrent With Chemotherapy for Esophageal Squamous Cell Carcinoma(ESO-Shanghai9) | completed | Phase 2 | 70 | Fudan UniversityOTHER | 1 | Dec 22, 2023 | clinicaltrials |
| NCT03783936 | Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas | completed | Phase 2 | 18 | Ashwin SomasundaramOTHER | 1 | Dec 19, 2023 | clinicaltrials |
| NCT03658837 | Gastrointestinal Functional Outcome Ivor Lewis | completed | — | 75 | University Hospitals, LeicesterOTHER | 1 | Dec 12, 2023 | clinicaltrials |
| NCT06165094 | Effect of Cervical Paraesophageal Lymph Node Metastasis Versus Supraclavicular Lymph Node Metastasis on the Overall Survival of Patients With Thoracic Esophageal Squamous Cell Carcinoma: An Observational Study(ECPLNMvsSLNM) | completed | — | 122 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Dec 11, 2023 | clinicaltrials |
| NCT01416077 | Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection | completed | Phase 4 | 64 | University Hospital, LinkoepingOTHER | 1 | Dec 4, 2023 | clinicaltrials |
| NCT02381249 | The Effect of Satiety Gut Hormone Modulation on Appetitive Drive After Upper Gastrointestinal Surgery | completed | N/A | 40 | St. James's Hospital, IrelandOTHER | 2 | Nov 27, 2023 | clinicaltrials |
| NCT02385617 | Food Intake and Gut Hormones in Patients Who Have Undergone Upper Gastrointestinal Surgery for Cancer | completed | N/A | 20 | St. James's Hospital, IrelandOTHER | 2 | Nov 27, 2023 | clinicaltrials |
| NCT02609425 | Intrathoracic Esophagogastric Anastomosis After Robot Assisted Minimally Invasive Esophagectomy Using STRATAFIX | completed | — | 30 | Henry Ford Health SystemOTHER | 1 | Nov 24, 2023 | clinicaltrials |
| NCT04187352 | A Study of CS1001 in Subjects With Esophageal Squamous Cell Carcinoma | completed | Phase 3 | 540 | CStone PharmaceuticalsINDUSTRY | 1 | Nov 24, 2023 | clinicaltrials |
| NCT03792347 | Preoperative Anti-PD-1 Antibody Combined With Chemoradiotherapy for Locally Advanced Squamous Cell Carcinoma of Esophagus(PALACE-1) | completed | Phase 1 | 20 | Hecheng Li M.D., Ph.DOTHER | 1 | Nov 22, 2023 | clinicaltrials |
| NCT05557955 | Identification of Breath Biomarkers in Esophageal Cancer(EC-CRT-005) | completed | — | 210 | Mian XIOTHER | 1 | Nov 18, 2023 | clinicaltrials |
| NCT01522768 | Afatinib and Paclitaxel in Patients With Advanced HER2-Positive Trastuzumab-Refractory Advanced Esophagogastric Cancer | completed | Phase 2 | 42 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 1, 2023 | clinicaltrials |
| NCT03748134 | Sintilimab or Placebo With Chemotherapy in Esophageal Squamous Cell Carcinoma ( ORIENT-15 ) | completed | Phase 3 | 746 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 7 | Oct 24, 2023 | clinicaltrials |
| NCT01401907 | Early Palliative Care in Advanced Lung and Gastrointestinal Malignancies | completed | N/A | 351 | Massachusetts General HospitalOTHER | 1 | Oct 19, 2023 | clinicaltrials |
| NCT05302011 | Neoadjuvant Pembrolizumab Plus Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 28 | Peking Union Medical College HospitalOTHER | 1 | Oct 10, 2023 | clinicaltrials |
| NCT03756597 | PAN-study: Pan-Cancer Early Detection Study (PAN) | completed | — | 268 | Owlstone LtdINDUSTRY | 1 | Oct 5, 2023 | clinicaltrials |
| NCT06060106 | Endoscopic Submucosal Dissection Versus Esophagectomy for Early Esophageal Carcinoma | completed | — | 191 | Changhai HospitalOTHER | 1 | Sep 29, 2023 | clinicaltrials |
| NCT02639065 | A Study of Durvalumab (MEDI4736) in Esophageal Cancer | completed | Phase 2 | 39 | Shadia Jalal, MDOTHER | 1 | Sep 25, 2023 | clinicaltrials |
| NCT02971956 | Pembrolizumab in Refractory Advanced Esophageal Cancer | completed | Phase 2 | 49 | Dana-Farber Cancer InstituteOTHER | 1 | Sep 21, 2023 | clinicaltrials |
| NCT02366039 | Probe-based Volumetric Laser Endomicroscopy (pVLE) of Endoscopic Mucosal Resection (EMR) Tissue in Patients With Barrett's Dysplasia(VLE EMR) | completed | — | 76 | Mayo ClinicOTHER | 1 | Sep 13, 2023 | clinicaltrials |
| NCT01047111 | Esophagectomy: Sweet Versus Ivor-Lewis (ESVIL) (ECTOP-2001) | completed | N/A | 300 | Fudan UniversityOTHER | 1 | Jul 20, 2023 | clinicaltrials |
| NCT01807936 | Esophagectomy:Three-field Versus Two-field Lymphadenectomy (ECTOP-2002) | completed | N/A | 400 | Fudan UniversityOTHER | 1 | Jul 20, 2023 | clinicaltrials |
| NCT03244566 | PET in Guiding Cervical Lymphadenectomy (ECTOP-2003) | completed | — | 110 | Fudan UniversityOTHER | 1 | Jul 13, 2023 | clinicaltrials |
| NCT04695847 | M1231 in Participants With Solid Tumors | completed | Phase 1 | 23 | EMD Serono Research & Development Institute, Inc.INDUSTRY | 2 | Jul 7, 2023 | clinicaltrials |
| NCT00063986 | Esophagectomy in Treating Patients With High-Grade Dysplasia of the Esophagus or Stage I, Stage II, or Stage III Esophageal Cancer | completed | Phase 2 | 110 | Eastern Cooperative Oncology GroupNETWORK | 1 | Jun 29, 2023 | clinicaltrials |
| NCT00033657 | Radiation Therapy and Chemotherapy Before and After Surgery in Treating Patients With Esophageal Cancer | completed | Phase 2 | 97 | Eastern Cooperative Oncology GroupNETWORK | 1 | Jun 28, 2023 | clinicaltrials |
| NCT00003237 | Combination Chemotherapy After Surgery in Treating Patients With Cancer of the Esophagus or Stomach | completed | Phase 2 | 55 | Eastern Cooperative Oncology GroupNETWORK | 3 | Jun 22, 2023 | clinicaltrials |
| NCT04440943 | A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies | completed | Phase 1 | 27 | Celldex TherapeuticsINDUSTRY | 1 | Jun 18, 2023 | clinicaltrials |
| NCT00003864 | Docetaxel Plus Carboplatin in Treating Patients With Advanced Cancer of the Esophagus | completed | Phase 2 | — | Eastern Cooperative Oncology GroupNETWORK | 3 | Jun 15, 2023 | clinicaltrials |
| NCT02850991 | Different Radiation Dose With Concurrent Chemotherapy for Thoracic Esophageal Carcinoma | completed | N/A | 167 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 13, 2023 | clinicaltrials |
| NCT00591981 | Thoracic OncoGeriatric Assessment (TOGA) Trials(TOGA) | completed | — | 14 | University of Wisconsin, MadisonOTHER | 1 | Jun 5, 2023 | clinicaltrials |
| NCT00318903 | Irinotecan and Taxotere With Radiotherapy as Preoperative Treatment in Resectable Esophageal Cancer | completed | Phase 2 | 25 | University of Alabama at BirminghamOTHER | 1 | May 25, 2023 | clinicaltrials |
| NCT04809870 | Esophagectomy in Patients With Liver Cirrhosis | completed | — | 170 | Universitätsklinikum Hamburg-EppendorfOTHER | 1 | May 23, 2023 | clinicaltrials |
| NCT05855278 | The Role of PET/MRI in Predicting the Outcome of Definitive Chemoradiotherapy for Esophageal Cancer Patients | completed | N/A | 22 | Chang Gung Memorial HospitalOTHER | 1 | May 11, 2023 | clinicaltrials |
| NCT05855291 | PET/MRI in Predicting the Outcome of Neoadjuvant Chemoradiotherapy With Esophagectomy in Esophageal Cancer Patients | completed | N/A | 43 | Chang Gung Memorial HospitalOTHER | 1 | May 11, 2023 | clinicaltrials |
| NCT05839002 | Primary Tumor Burden Score:A Novel Staging Parameter for ESCC After nCRT | completed | — | 187 | Fudan UniversityOTHER | 0 | May 3, 2023 | clinicaltrials |
| NCT02853474 | Early Palliative Care in Patients With Metastatic Upper Gastrointestinal Cancers Treated With First-line Chemotherapy(EPIC-1511) | completed | Phase 3 | 480 | Centre Oscar LambretOTHER | 1 | Apr 26, 2023 | clinicaltrials |
| NCT01333033 | PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy | completed | Phase 2 | 257 | Alliance for Clinical Trials in OncologyOTHER | 1 | Apr 13, 2023 | clinicaltrials |
| NCT02937389 | Endoscopic Evaluation for Predicting the Complications Related to Gastric Conduit After Esophagectomy | completed | — | 60 | Nagasaki UniversityOTHER | 1 | Apr 5, 2023 | clinicaltrials |
| NCT02284802 | Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy | completed | N/A | 87 | Fauze Maluf FilhoOTHER | 1 | Mar 23, 2023 | clinicaltrials |
| NCT03888092 | Z650 in Advanced Esophageal Squamous Cell Carcinoma With EGFR Over Expression or Gene Amplification | completed | Phase 1 / Phase 2 | 81 | Sunshine Lake Pharma Co., Ltd.INDUSTRY | 1 | Mar 21, 2023 | clinicaltrials |
Data updated 23 days agoSource updated Jan 26, 2024source: clinicaltrials