Subtype
Esophageal Carcinoma
CI-CAN-00002609ESCAExplore in graph →
307 active trials4 approved drugs11 evidence items
- NCIt
- C3513
- DOID
- 1107
- Other
- 1 more code
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Subtype
CI-CAN-00002609ESCAExplore in graph →
Clinical trials
807 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (62)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04199832 | To Compare the Effect of Different Nutritional Pathways on Improving Nutritional Status of Esophageal Cancer Patients Undergoing Chemoradiotherapy | completed | — | 156 | Tianjin Medical University Cancer Institute and HospitalOTHER | 1 | Feb 16, 2023 | clinicaltrials |
| NCT04764643 | The Efficacy of N-acetylcysteine on Alleviating Symptom Caused by Lugol Chromoendoscopy | completed | N/A | 140 | Xijing Hospital of Digestive DiseasesOTHER | 1 |
| Jan 30, 2023 |
| clinicaltrials |
| NCT04293458 | Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BE(ESOGUARDBE1) | completed | N/A | 145 | Lucid Diagnostics, Inc.INDUSTRY | 2 | Jan 25, 2023 | clinicaltrials |
| NCT04380480 | Percutaneous Endoscopic Gastrostomy Before Definitive Concurrent Chemoradiation Therapy for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 63 | Sun Yat-sen UniversityOTHER | 1 | Jan 11, 2023 | clinicaltrials |
| NCT03160209 | HIV and Other Risk Factors for Esophageal Squamous Cell Carcinoma in Malawi | completed | — | 600 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Jan 6, 2023 | clinicaltrials |
| NCT00586872 | Endoscopic Mucosal Resection (EMR) in Barrett's Esophagus | completed | — | 1,000 | Mayo ClinicOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT03762564 | Study With Paclitaxel +/- Ramucirumab in Patients With Squamous-cell Carcinoma of the Esophagus After Prior Therapy(RAMOS) | completed | Phase 2 | 21 | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus NordwestOTHER | 1 | Dec 8, 2022 | clinicaltrials |
| NCT05628441 | Real-time Computer Aided Detection of Barrett's Neoplasia | completed | — | 30 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Nov 28, 2022 | clinicaltrials |
| NCT05604950 | Surgery Versus Non-surgical Treatment for Esophageal Squamous Cell Carcinoma in Patients Older Than 70 Years | completed | — | 2 | Yongtao HanOTHER | 0 | Nov 3, 2022 | clinicaltrials |
| NCT03660449 | Moderately Hypofractionated Conformal Radiation Combined With S-1 for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 58 | Sun Yat-sen UniversityOTHER | 1 | Oct 26, 2022 | clinicaltrials |
| NCT02513784 | Trial to Assess the Effects of an Antimicrobial Mouthwash on the Esophageal Microbiome(Mouthwash) | completed | N/A | 20 | Columbia UniversityOTHER | 1 | Sep 22, 2022 | clinicaltrials |
| NCT04609813 | Esophageal cAncer Screening Trial(EAST) | completed | — | 14,597 | Changhai HospitalOTHER | 1 | Sep 21, 2022 | clinicaltrials |
| NCT02559687 | Study of Pembrolizumab (MK-3475) in Previously-Treated Participants With Advanced Carcinoma of the Esophagus or Esophagogastric Junction (MK-3475-180/KEYNOTE-180) | completed | Phase 2 | 121 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Sep 14, 2022 | clinicaltrials |
| NCT01212822 | Bevacizumab and Combination Chemotherapy Before Surgery in Treating Patients With Locally Advanced Esophageal or Stomach Cancer | completed | Phase 2 | 20 | Fox Chase Cancer CenterOTHER | 1 | Sep 7, 2022 | clinicaltrials |
| NCT03925870 | KN046 in Subjects With Late Stage Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 45 | Jiangsu Alphamab Biopharmaceuticals Co., LtdINDUSTRY | 1 | Aug 5, 2022 | clinicaltrials |
| NCT03365791 | PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies | completed | Phase 2 | 76 | Novartis PharmaceuticalsINDUSTRY | 1 | May 27, 2022 | clinicaltrials |
| NCT04936399 | A Study of Participants With Squamous Cell Oesophageal Carcinoma Receiving Nivolumab as Part of an Early Access to Medicines Scheme (EAMS) Program in the United Kingdom | completed | — | 87 | Bristol-Myers SquibbINDUSTRY | 1 | May 25, 2022 | clinicaltrials |
| NCT01137123 | Improve the Treatment of Thoracic Esophageal Cancer | completed | Phase 3 | 301 | Sun Yat-sen UniversityOTHER | 1 | Mar 31, 2022 | clinicaltrials |
| NCT02459457 | A Comparison of Paclitaxel-based Three Regimens Concurrent With Radiotherapy for Patients With Local Advanced Esophageal Cancer | completed | Phase 3 | 321 | Fudan UniversityOTHER | 1 | Feb 9, 2022 | clinicaltrials |
| NCT04196075 | The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer(AP) | completed | Phase 3 | 30 | Chinese University of Hong KongOTHER | 1 | Nov 8, 2021 | clinicaltrials |
| NCT03008980 | WATS3D for the Detection of Esophageal Dysplasia | completed | — | 160 | CDx DiagnosticsINDUSTRY | 1 | Nov 4, 2021 | clinicaltrials |
| NCT00591123 | Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia | completed | Phase 2 | 38 | Translational Oncology Research InternationalOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT04090554 | Cytosponge™ Feasibility Study in Tanzania(CytoSCCAPE) | completed | N/A | 101 | International Agency for Research on CancerOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT00487695 | Confocal Endomicroscopy for Barrett's Esophagus(CEBE) | completed | Phase 3 | 46 | Johns Hopkins UniversityOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04669951 | Urokinase-type Plasminogen Activator Receptor and Gastroesophageal Cancer | completed | N/A | 100 | Michael Patrick AchiamOTHER | 1 | Jun 3, 2021 | clinicaltrials |
| NCT02128243 | Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer(MATEO) | completed | Phase 2 | 242 | AIO-Studien-gGmbHOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT02645864 | Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Peking UniversityOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT04764240 | Precisely Estimation of the Prognostic Value of Lymph Node in ESCC | completed | — | 3,700 | Shanghai Cancer Hospital, ChinaOTHER | 0 | Feb 23, 2021 | clinicaltrials |
| NCT02644408 | Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy | completed | Phase 3 | 184 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT03116152 | Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment | completed | Phase 2 | 190 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 1 | Feb 3, 2021 | clinicaltrials |
| NCT04225364 | Efficacy of Neoadjuvant PD-1 Blockade Plus Chemotherapy for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 56 | Guangzhou Institute of Respiratory DiseaseOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT01766986 | Staging and Outcome Depending on Surgical Treatment in Adenocarcinomas of the Oesophagogastric Junction | completed | — | 130 | Universitätsklinikum Hamburg-EppendorfOTHER | 0 | Jan 6, 2021 | clinicaltrials |
| NCT01598077 | A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer | completed | Phase 1 | 54 | Novartis PharmaceuticalsINDUSTRY | 5 | Dec 19, 2020 | clinicaltrials |
| NCT01822613 | Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC) | completed | Phase 1 | 48 | Novartis PharmaceuticalsINDUSTRY | 9 | Dec 19, 2020 | clinicaltrials |
| NCT02890979 | Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease | completed | N/A | 11 | OHSU Knight Cancer InstituteOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT02606916 | Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer. | completed | Phase 2 | 42 | Sun Yat-sen UniversityOTHER | 1 | Sep 4, 2020 | clinicaltrials |
| NCT02658214 | Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors | completed | Phase 1 | 32 | AstraZenecaINDUSTRY | 2 | Aug 20, 2020 | clinicaltrials |
| NCT03187314 | Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer | completed | Phase 2 | 25 | Hangzhou Cancer HospitalOTHER | 1 | Aug 17, 2020 | clinicaltrials |
| NCT02120911 | Feasibility Study of Chemoradiation, TRAstuzumab and Pertuzumab in Resectable HER2+ Esophageal Carcinoma(TRAP) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Jul 1, 2020 | clinicaltrials |
| NCT02047305 | Radiofrequency Ablation for Patients With Esophageal Squamous Cell Neoplasia | completed | N/A | 96 | Covidien, GI SolutionsINDUSTRY | 1 | May 21, 2020 | clinicaltrials |
| NCT02964455 | Study of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Sun Yat-sen UniversityOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT00901173 | A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya | completed | — | 372 | National Cancer Institute (NCI)NIH | 1 | Apr 24, 2020 | clinicaltrials |
| NCT01544790 | Robot-assisted Thoraco-laparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy(ROBOT) | completed | Phase 3 | 112 | UMC UtrechtOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT02399306 | Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma | completed | Phase 3 | 222 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT03526328 | DCLK1 as a Marker/Indicator of Stem Cell Response in Barrett's Esophagus/Esophageal Adenocarcinoma | completed | — | 32 | University of OklahomaOTHER | 1 | Mar 6, 2020 | clinicaltrials |
| NCT01362127 | Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia(NeoRes) | completed | Phase 2 | 181 | Karolinska University HospitalOTHER | 1 | Feb 26, 2020 | clinicaltrials |
| NCT01855854 | Second-line Treatment With Icotinib in Esophageal Carcinoma Patients With EGFR Overexpression (IHC 3+) or Positive FISH | completed | Phase 2 | 54 | Betta Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Jul 5, 2019 | clinicaltrials |
| NCT02649361 | Study of Anlotinib in Patients With Esophageal Squamous Cell Carcinoma (ALTER1102) | completed | Phase 2 | 164 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Jun 5, 2019 | clinicaltrials |
| NCT03584308 | Efficacy of VIUSID® Plus GLIZIGEN® in Patients With Papilloma Virus Esophageal | completed | Phase 2 | 110 | Catalysis SLINDUSTRY | 1 | May 22, 2019 | clinicaltrials |
Data updated 22 days agoSource updated Feb 16, 2023source: clinicaltrials