Subtype
Esophageal and Gastroesophageal Junction Carcinoma
CI-CAN-00002608Explore in graph →
460 active trials11 approved drugs34 evidence items
- NCIt
- C203673
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Subtype
CI-CAN-00002608Explore in graph →
Clinical trials
1,309 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (120)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01804998 | Multicenter Phase III Trial of Laparoscopic Sentinel Node Biopsy | completed | N/A | 580 | National Cancer Center, KoreaOTHER_GOV | 1 | Feb 15, 2022 | clinicaltrials |
| NCT02459457 | A Comparison of Paclitaxel-based Three Regimens Concurrent With Radiotherapy for Patients With Local Advanced Esophageal Cancer | completed | Phase 3 | 321 | Fudan UniversityOTHER | 1 | Feb 9, 2022 | clinicaltrials |
| NCT03319459 |
| FATE-NK100 as Monotherapy and in Combination With Monoclonal Antibody in Subjects With Advanced Solid Tumors |
| completed |
| Phase 1 |
| 44 |
| Fate TherapeuticsINDUSTRY |
| 1 |
| Nov 22, 2021 |
| clinicaltrials |
| NCT04196075 | The Effect of Andrographis Paniculata (AP) on Palliative Management of Advanced Esophageal Cancer(AP) | completed | Phase 3 | 30 | Chinese University of Hong KongOTHER | 1 | Nov 8, 2021 | clinicaltrials |
| NCT03008980 | WATS3D for the Detection of Esophageal Dysplasia | completed | — | 160 | CDx DiagnosticsINDUSTRY | 1 | Nov 4, 2021 | clinicaltrials |
| NCT00591123 | Study of Erlotinib and Chemotherapy for Unresectable or Metastatic Cancer of the Esophagus and Gastric Cardia | completed | Phase 2 | 38 | Translational Oncology Research InternationalOTHER | 1 | Oct 1, 2021 | clinicaltrials |
| NCT02314117 | A Study of Ramucirumab (LY3009806) in Combination With Capecitabine and Cisplatin in Participants With Stomach Cancer(RAINFALL) | completed | Phase 3 | 645 | Eli Lilly and CompanyINDUSTRY | 20 | Aug 26, 2021 | clinicaltrials |
| NCT04090554 | Cytosponge™ Feasibility Study in Tanzania(CytoSCCAPE) | completed | N/A | 101 | International Agency for Research on CancerOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT01631552 | Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer | completed | Phase 1 / Phase 2 | 515 | Gilead SciencesINDUSTRY | 1 | Aug 12, 2021 | clinicaltrials |
| NCT00487695 | Confocal Endomicroscopy for Barrett's Esophagus(CEBE) | completed | Phase 3 | 46 | Johns Hopkins UniversityOTHER | 1 | Jun 22, 2021 | clinicaltrials |
| NCT04920747 | Interest of the Addition of Docetaxel to Standard Treatment in First-line Advanced HER2 Positive Gastroesophageal Adenocarcinoma in Selective Patients(TandHER) | completed | — | 65 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Jun 10, 2021 | clinicaltrials |
| NCT04669951 | Urokinase-type Plasminogen Activator Receptor and Gastroesophageal Cancer | completed | N/A | 100 | Michael Patrick AchiamOTHER | 1 | Jun 3, 2021 | clinicaltrials |
| NCT02564367 | Feasibility Study of Adjuvant Treatment With S-1 in Patients After R0-Resection of Adenocarcinoma of the Stomach and Esophagogastric Junction(S-1 adjuvant) | completed | Phase 1 / Phase 2 | 30 | AIO-Studien-gGmbHOTHER | 1 | Apr 29, 2021 | clinicaltrials |
| NCT02128243 | Trial of S-1 Maintenance Therapy in Metastatic Esophagogastric Cancer(MATEO) | completed | Phase 2 | 242 | AIO-Studien-gGmbHOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT02645864 | Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Peking UniversityOTHER | 1 | Mar 18, 2021 | clinicaltrials |
| NCT04764240 | Precisely Estimation of the Prognostic Value of Lymph Node in ESCC | completed | — | 3,700 | Shanghai Cancer Hospital, ChinaOTHER | 0 | Feb 23, 2021 | clinicaltrials |
| NCT02644408 | Megestrol Acetate for the Improvement of Quality of Life in Esophageal Cancer With Chemoradiotherapy | completed | Phase 3 | 184 | The First Affiliated Hospital of Henan University of Science and TechnologyOTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT03116152 | Study of IBI308 With Advanced/Metastatic Esophageal Squamous Cell Carcinoma After Failure of First-line Treatment | completed | Phase 2 | 190 | Innovent Biologics (Suzhou) Co. Ltd.INDUSTRY | 1 | Feb 3, 2021 | clinicaltrials |
| NCT00061932 | Bortezomib With or Without Irinotecan in Treating Patients With Cancer of the Gastroesophageal Junction or Stomach | completed | Phase 2 | 41 | National Cancer Institute (NCI)NIH | 1 | Feb 2, 2021 | clinicaltrials |
| NCT04225364 | Efficacy of Neoadjuvant PD-1 Blockade Plus Chemotherapy for Esophageal Squamous Cell Carcinoma | completed | Phase 2 | 56 | Guangzhou Institute of Respiratory DiseaseOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT03083613 | Raltitrexed and Paclitaxel for Gastric or Gastroesophageal Junction Adenocarcinoma | completed | Phase 2 | 41 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT02234596 | Nintedanib in Patients With Advanced Esophagogastric Cancer | completed | Phase 2 | 34 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jan 25, 2021 | clinicaltrials |
| NCT01183559 | A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery | completed | Phase 1 | 9 | Fox Chase Cancer CenterOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT02572687 | A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies | completed | Phase 1 | 85 | Eli Lilly and CompanyINDUSTRY | 8 | Jan 20, 2021 | clinicaltrials |
| NCT01766986 | Staging and Outcome Depending on Surgical Treatment in Adenocarcinomas of the Oesophagogastric Junction | completed | — | 130 | Universitätsklinikum Hamburg-EppendorfOTHER | 0 | Jan 6, 2021 | clinicaltrials |
| NCT01598077 | A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer | completed | Phase 1 | 54 | Novartis PharmaceuticalsINDUSTRY | 5 | Dec 19, 2020 | clinicaltrials |
| NCT01822613 | Study of Safety & Efficacy of the Combination of LJM716 & BYL719 in Patients With Previously Treated Esophageal Squamous Cell Carcinoma (ESCC) | completed | Phase 1 | 48 | Novartis PharmaceuticalsINDUSTRY | 9 | Dec 19, 2020 | clinicaltrials |
| NCT02082210 | A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer | completed | Phase 1 / Phase 2 | 97 | Eli Lilly and CompanyINDUSTRY | 1 | Dec 19, 2020 | clinicaltrials |
| NCT02890979 | Swallowable Sponge Cell Sampling Device and Next Generation Sequencing in Detecting Esophageal Cancer in Patients With Low or High Grade Dysplasia, Barrett Esophagus, or Gastroesophageal Reflux Disease | completed | N/A | 11 | OHSU Knight Cancer InstituteOTHER | 1 | Nov 25, 2020 | clinicaltrials |
| NCT01107639 | Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery | completed | Phase 3 | 297 | Swiss Cancer InstituteOTHER | 5 | Oct 20, 2020 | clinicaltrials |
| NCT01364324 | Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized Patients | completed | — | 40 | National Cancer Center, KoreaOTHER_GOV | 1 | Sep 25, 2020 | clinicaltrials |
| NCT02606916 | Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer. | completed | Phase 2 | 42 | Sun Yat-sen UniversityOTHER | 1 | Sep 4, 2020 | clinicaltrials |
| NCT02658214 | Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors | completed | Phase 1 | 32 | AstraZenecaINDUSTRY | 2 | Aug 20, 2020 | clinicaltrials |
| NCT03187314 | Combination of Radiation Therapy and Anti-PD-1 Antibody SHR-1210 in Treating Patients With Esophageal Cancer | completed | Phase 2 | 25 | Hangzhou Cancer HospitalOTHER | 1 | Aug 17, 2020 | clinicaltrials |
| NCT02629315 | Carnoy's Solution Versus Formalin in Rectal and Gastric Cancer Specimens Following: a Randomized Trial | completed | N/A | 130 | Instituto do Cancer do Estado de São PauloOTHER | 0 | Jul 23, 2020 | clinicaltrials |
| NCT02120911 | Feasibility Study of Chemoradiation, TRAstuzumab and Pertuzumab in Resectable HER2+ Esophageal Carcinoma(TRAP) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Jul 1, 2020 | clinicaltrials |
| NCT02443883 | A Phase 2 Study of Ramucirumab (LY3009806) in Participants With Gastric or Gastroesophageal Junction (GEJ) Cancer | completed | Phase 2 | 164 | Eli Lilly and CompanyINDUSTRY | 12 | Jun 29, 2020 | clinicaltrials |
| NCT02514551 | A Study of Ramucirumab (LY3009806) in Combination With Paclitaxel in Participants With Gastric Cancer | completed | Phase 2 | 245 | Eli Lilly and CompanyINDUSTRY | 11 | Jun 17, 2020 | clinicaltrials |
| NCT02545504 | Andecaliximab With mFOLFOX6 as First Line Treatment for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma(GAMMA-1) | completed | Phase 3 | 432 | Gilead SciencesINDUSTRY | 16 | May 26, 2020 | clinicaltrials |
| NCT02047305 | Radiofrequency Ablation for Patients With Esophageal Squamous Cell Neoplasia | completed | N/A | 96 | Covidien, GI SolutionsINDUSTRY | 1 | May 21, 2020 | clinicaltrials |
| NCT02964455 | Study of Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma | completed | Phase 1 | 12 | Sun Yat-sen UniversityOTHER | 1 | May 15, 2020 | clinicaltrials |
| NCT01643499 | Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies | completed | Phase 1 | 79 | University of ChicagoOTHER | 1 | May 8, 2020 | clinicaltrials |
| NCT00901173 | A Pilot for a Case-Control Study of Esophageal Squamous Cell Carcinoma in Western Kenya | completed | — | 372 | National Cancer Institute (NCI)NIH | 1 | Apr 24, 2020 | clinicaltrials |
| NCT01544790 | Robot-assisted Thoraco-laparoscopic Esophagectomy Versus Open Transthoracic Esophagectomy(ROBOT) | completed | Phase 3 | 112 | UMC UtrechtOTHER | 1 | Mar 26, 2020 | clinicaltrials |
| NCT02399306 | Chemoradiotherapy With or Without Enteral Nutrition for Locally Advanced Thoracic Esophageal Carcinoma | completed | Phase 3 | 222 | Sichuan Cancer Hospital and Research InstituteOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT03526328 | DCLK1 as a Marker/Indicator of Stem Cell Response in Barrett's Esophagus/Esophageal Adenocarcinoma | completed | — | 32 | University of OklahomaOTHER | 1 | Mar 6, 2020 | clinicaltrials |
| NCT01362127 | Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia(NeoRes) | completed | Phase 2 | 181 | Karolinska University HospitalOTHER | 1 | Feb 26, 2020 | clinicaltrials |
| NCT00515411 | Study of Modified Docetaxel, Cisplatin, and Fluorouracil (mDCF) in Unresectable or Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma | completed | Phase 2 | 111 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 10, 2019 | clinicaltrials |
| NCT01498289 | S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer | completed | Phase 2 | 213 | SWOG Cancer Research NetworkNETWORK | 1 | Nov 7, 2019 | clinicaltrials |
Data updated 23 days agoSource updated Feb 15, 2022source: clinicaltrials