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Genomics
2 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
516 cases with simple somatic mutation data · 516 cases total · Data Release 46.0 · mapped to Low Grade Glioma CURATED_BROADER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | IDH1 | Ssm | 402 | 516 | 77.9% | gdc |
| 2 | NLRP5 | Ssm | 284 | 516 | 55% | gdc |
| 3 | NLRP2 | Ssm | 283 | 516 | 54.8% | gdc |
| 4 | PPP1R12C | Ssm | 282 | 516 | 54.7% | gdc |
| 5 | NLRP11 | Ssm | 282 | 516 | 54.7% | gdc |
| 6 | PEG3 | Ssm | 282 | 516 | 54.7% | gdc |
| 7 | NLRP8 | Ssm | 282 | 516 | 54.7% | gdc |
| 8 | ZNF671 | Ssm |
Data updated 22 days agoSource updated Data Release 46.0
96 cases with simple somatic mutation data · 96 cases total · 2026-01-12 · mapped to Pilocytic Astrocytoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | BRAF |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 281 |
| 516 |
| 54.5% |
| gdc |
| 9 | LILRA1 | Ssm | 281 | 516 | 54.5% | gdc |
| 10 | EPS8L1 | Ssm | 281 | 516 | 54.5% | gdc |
| 11 | NLRP9 | Ssm | 281 | 516 | 54.5% | gdc |
| 12 | ZNF551 | Ssm | 281 | 516 | 54.5% | gdc |
| 13 | FIZ1 | Ssm | 281 | 516 | 54.5% | gdc |
| 14 | ZNF460 | Ssm | 281 | 516 | 54.5% | gdc |
| 15 | NLRP7 | Ssm | 281 | 516 | 54.5% | gdc |
| 16 | ZSCAN1 | Ssm | 281 | 516 | 54.5% | gdc |
| 17 | NLRP13 | Ssm | 281 | 516 | 54.5% | gdc |
| 18 | ZNF581 | Ssm | 281 | 516 | 54.5% | gdc |
| 19 | ZNF470 | Ssm | 281 | 516 | 54.5% | gdc |
| 20 | ZNF667 | Ssm | 281 | 516 | 54.5% | gdc |
| 21 | NLRP4 | Ssm | 281 | 516 | 54.5% | gdc |
| 22 | PTPRH | Ssm | 281 | 516 | 54.5% | gdc |
| 23 | GP6 | Ssm | 281 | 516 | 54.5% | gdc |
| 24 | FAM71E2 | Ssm | 280 | 516 | 54.3% | gdc |
| 25 | SBK2 | Ssm | 280 | 516 | 54.3% | gdc |
| 26 | ZNF416 | Ssm | 280 | 516 | 54.3% | gdc |
| 27 | ZNF264 | Ssm | 280 | 516 | 54.3% | gdc |
| 28 | SHISA7 | Ssm | 280 | 516 | 54.3% | gdc |
| 29 | EPN1 | Ssm | 280 | 516 | 54.3% | gdc |
| 30 | CCDC106 | Ssm | 280 | 516 | 54.3% | gdc |
| Ssm |
| 7 |
| 96 |
| 7.3% |
| cbioportal |
| 2 | FGFR1 | Ssm | 5 | 96 | 5.2% | cbioportal |
| 3 | NF1 | Ssm | 3 | 96 | 3.1% | cbioportal |
| 4 | ABCB7 | Ssm | 2 | 96 | 2.1% | cbioportal |
| 5 | IL4R | Ssm | 2 | 96 | 2.1% | cbioportal |
| 6 | KIAA1549 | Ssm | 2 | 96 | 2.1% | cbioportal |
| 7 | KRAS | Ssm | 2 | 96 | 2.1% | cbioportal |
| 8 | PTPN11 | Ssm | 2 | 96 | 2.1% | cbioportal |
| 9 | SETD2 | Ssm | 2 | 96 | 2.1% | cbioportal |
| 10 | ABCA6 | Ssm | 1 | 96 | 1% | cbioportal |
| 11 | ABCC1 | Ssm | 1 | 96 | 1% | cbioportal |
| 12 | ACD | Ssm | 1 | 96 | 1% | cbioportal |
| 13 | ADAMTS5 | Ssm | 1 | 96 | 1% | cbioportal |
| 14 | ADGRB3 | Ssm | 1 | 96 | 1% | cbioportal |
| 15 | ADGRE2 | Ssm | 1 | 96 | 1% | cbioportal |
| 16 | ADGRG4 | Ssm | 1 | 96 | 1% | cbioportal |
| 17 | AHNAK2 | Ssm | 1 | 96 | 1% | cbioportal |
| 18 | AK7 | Ssm | 1 | 96 | 1% | cbioportal |
| 19 | AKAP7 | Ssm | 1 | 96 | 1% | cbioportal |
| 20 | AMBP | Ssm | 1 | 96 | 1% | cbioportal |
| 21 | ANGPTL1 | Ssm | 1 | 96 | 1% | cbioportal |
| 22 | ANKRD36 | Ssm | 1 | 96 | 1% | cbioportal |
| 23 | APOB | Ssm | 1 | 96 | 1% | cbioportal |
| 24 | ARAP1 | Ssm | 1 | 96 | 1% | cbioportal |
| 25 | ATP2B3 | Ssm | 1 | 96 | 1% | cbioportal |
| 26 | BBS2 | Ssm | 1 | 96 | 1% | cbioportal |
| 27 | BCOR | Ssm | 1 | 96 | 1% | cbioportal |
| 28 | BRD10 | Ssm | 1 | 96 | 1% | cbioportal |
| 29 | C6 | Ssm | 1 | 96 | 1% | cbioportal |
| 30 | CBX4 | Ssm | 1 | 96 | 1% | cbioportal |
Data updated 22 days agoSource updated 2026-01-12