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Embryonal Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Embryonal Neoplasm

Cancer Family

Embryonal Neoplasm

CI-CAN-00000013Explore in graph →

Non-malignant285 active trials7 approved drugs73 evidence items

NCIt: C3264
OncoTree: EMBT
UMLS CUI: C0027654

Overview
Statistics
Survival
Genomics22
Variants & evidence73
Drugs28
Trials1126
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (70)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 26–50 of 70 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

ETV6-NTRK3 in congenital mesoblastic nephroma: A report of the SIOP/GPOH nephroblastoma study.
· Pediatr Blood Cancer · 2018 · PMID 29286563 · validated civic_curation pubmed
High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis.
· Brain Pathol · 2020 · PMID 31104347 · validated civic_curation pubmed
Congenital mesoblastic nephroma: a study of 19 cases using immunohistochemistry and ETV6-NTRK3 fusion gene rearrangement.
· Pathology · 2016 · PMID 27020209 · validated civic_curation pubmed
CNS high-grade neuroepithelial tumor with BCOR internal tandem duplication: a comparison with its counterparts in the kidney and soft tissue.
· Brain Pathol · 2018 · PMID 29226988 · validated civic_curation pubmed
Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
· J Clin Oncol · 2015 · PMID 26169613 · validated civic_curation pubmed
Detection of t(11;22)(q24;q12) translocation of Ewing's sarcoma in paraffin embedded tissue by nested reverse transcription-polymerase chain reaction.
· J Korean Med Sci · 1998 · PMID 9741544 · validated civic_curation pubmed
Phase II study on lapatinib in advanced EGFR-positive chordoma.
· Ann Oncol · 2013 · PMID 23559153

Showing 26–50 of 70 publications

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· validated civic_curation

Congenital mesoblastic nephroma is characterised by kinase mutations including EGFR internal tandem duplications, the ETV6-NTRK3 fusion, and the rare KLHL7-BRAF fusion.

· Histopathology · 2020 · PMID 32590884 · validated civic_curation pubmed

Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications.

· Oncotarget · 2013 · PMID 23800680 · validated civic_curation pubmed

Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib.

· Cold Spring Harb Mol Case Stud · 2018 · PMID 29907598 · validated civic_curation pubmed

Dramatic bone remodeling following larotrectinib administration for bone metastasis in a patient with TRK fusion congenital mesoblastic nephroma.

· Pediatr Blood Cancer · 2018 · PMID 29893456 · validated civic_curation pubmed

Cribriform neuroepithelial tumor: molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome.

· Brain Pathol · 2017 · PMID 27380723 · validated civic_curation pubmed

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

· Science · 2009 · PMID 19726788 · validated civic_curation pubmed

Recurrent EML4-NTRK3 fusions in infantile fibrosarcoma and congenital mesoblastic nephroma suggest a revised testing strategy.

· Mod Pathol · 2018 · PMID 29099503 · validated civic_curation pubmed

Cribriform neuroepithelial tumor (CRINET): a nonrhabdoid ventricular tumor with INI1 loss and relatively favorable prognosis.

· J Neuropathol Exp Neurol · 2009 · PMID 19915490 · validated civic_curation pubmed

High-Resolution Genomic Analysis of Cribriform Neuroepithelial Tumors of the Central Nervous System.

· J Neuropathol Exp Neurol · 2015 · PMID 26352987 · validated civic_curation pubmed

Ewing sarcoma with ERG gene rearrangements: A molecular study focusing on the prevalence of FUS-ERG and common pitfalls in detecting EWSR1-ERG fusions by FISH.

· Genes Chromosomes Cancer · 2016 · PMID 26690869 · validated civic_curation pubmed

Activating mutations in ALK provide a therapeutic target in neuroblastoma.

· Nature · 2008 · PMID 18923525 · validated civic_curation pubmed

The ALK/ROS1 Inhibitor PF-06463922 Overcomes Primary Resistance to Crizotinib in ALK-Driven Neuroblastoma.

· Cancer Discov · 2016 · PMID 26554404 · validated civic_curation pubmed

CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.

· Cancer Cell · 2011 · PMID 21575866 · validated civic_curation pubmed

ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.

· Clin Cancer Res · 2011 · PMID 21948233 · validated civic_curation pubmed

Differential inhibitor sensitivity of anaplastic lymphoma kinase variants found in neuroblastoma.

· Sci Transl Med · 2011 · PMID 22072639 · validated civic_curation pubmed

Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.

· Sci Transl Med · 2015 · PMID 26537256 · validated civic_curation pubmed

Caspase-8 expression is predictive of tumour response to death receptor 5 agonist antibody in Ewing's sarcoma.

· Br J Cancer · 2015 · PMID 26291055 · validated civic_curation pubmed

Targeting the mTOR Complex by Everolimus in NRAS Mutant Neuroblastoma.

· PLoS One · 2016 · PMID 26821351 · validated civic_curation pubmed