Hematologic Malignancy
Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Molecular Subtypes
CI-CAN-00008842Explore in graph →
Hematologic5 active trials
- NCIt
- C148392
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Hematologic Malignancy
CI-CAN-00008842Explore in graph →
Variants & evidence
2 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CD79B MUTATION1 | ||||||||
| (diagnostic) | MCD Diffuse Large B-Cell Lymphoma | Diagnostic | E | Supports Positive | 3 | submitted | EID11822This is one of the genetic features of this subgroup PMID 32289277 · Wright et al., 2020 · Open in CIViC | civic |
| GNAI2 mutation1 | ||||||||
| (oncogenic) | EZB Diffuse Large B-Cell Lymphoma | Oncogenic | E | Supports Oncogenicity | 4 | submitted | EID11943The study identified recurrently mutated genes in DLBCL using whole genome sequencing. PMID 23699601 · Morin et al., 2013 · Open in CIViC | civic |
Data updated 5 hours agoSource updated unknownsource: civic (CC0)
Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.