Subtype
Diffuse Glioma
CI-CAN-00002519Explore in graph →
Non-malignant787 active trials5 approved drugs147 evidence items
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Subtype
CI-CAN-00002519Explore in graph →
Clinical trials
2,805 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02709616 | Personalized Cellular Vaccine for Glioblastoma (PERCELLVAC)(PERCELLVAC) | completed | Phase 1 | 10 | Guangdong 999 Brain HospitalOTHER | 1 | May 27, 2022 | clinicaltrials |
| NCT02808364 | Personalized Cellular Vaccine for Recurrent Glioblastoma (PERCELLVAC2)(PerCellVac2) | completed | Phase 1 | 10 | Guangdong 999 Brain HospitalOTHER | 1 | May 27, 2022 |
| clinicaltrials |
| NCT03775369 | Glioma and Exercising | completed | N/A | 39 | University Hospital, Basel, SwitzerlandOTHER | 1 | May 18, 2022 | clinicaltrials |
| NCT02871843 | RRx-001 + Radiation + Temozolomide In Newly Diagnosed Glioblastoma and Anaplastic Gliomas(G-FORCE-1) | completed | Phase 1 | 19 | EpicentRx, Inc.INDUSTRY | 1 | May 16, 2022 | clinicaltrials |
| NCT03216499 | HIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma(PT2385) | completed | Phase 2 | 24 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | May 9, 2022 | clinicaltrials |
| NCT02155452 | Fluorescence and Glioma Heterogeneity(ALAglioma) | completed | — | 25 | Tata Memorial HospitalOTHER_GOV | 1 | May 6, 2022 | clinicaltrials |
| NCT02415153 | Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors | completed | Phase 1 | 29 | National Cancer Institute (NCI)NIH | 1 | Apr 25, 2022 | clinicaltrials |
| NCT04013828 | Treatment Decision-making in Patients With Recurrent High-grade Glioma | completed | — | 29 | Odense University HospitalOTHER | 1 | Apr 20, 2022 | clinicaltrials |
| NCT02794883 | Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma | completed | Phase 2 | 36 | Northwestern UniversityOTHER | 1 | Apr 18, 2022 | clinicaltrials |
| NCT03390569 | Exercise in Patients With Glioblastoma | completed | N/A | 54 | University Health Network, TorontoOTHER | 1 | Apr 14, 2022 | clinicaltrials |
| NCT01004874 | Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma | completed | Phase 2 | 80 | Duke UniversityOTHER | 1 | Apr 13, 2022 | clinicaltrials |
| NCT02750891 | A Study of DSP-7888 in Pediatric Patients With Relapsed or Refractory High Grade Gliomas | completed | Phase 1 / Phase 2 | 18 | Sumitomo Pharma Co., Ltd.INDUSTRY | 1 | Apr 12, 2022 | clinicaltrials |
| NCT05028400 | Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery(LSCI-NSURG) | completed | N/A | 20 | Insel Gruppe AG, University Hospital BernOTHER | 1 | Apr 12, 2022 | clinicaltrials |
| NCT02843230 | Monitoring Anti-angiogenic Therapy in Brain Tumors by Advanced MRI | completed | — | 30 | Massachusetts General HospitalOTHER | 1 | Apr 8, 2022 | clinicaltrials |
| NCT01904123 | STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain | completed | Phase 1 | 8 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 23, 2022 | clinicaltrials |
| NCT00303849 | Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors | completed | Phase 1 / Phase 2 | 33 | OHSU Knight Cancer InstituteOTHER | 1 | Mar 17, 2022 | clinicaltrials |
| NCT02359097 | Steady State Blood Volume Maps Using Ferumoxytol Non-stoichiometric Magnetite MRI in Imaging Patients With Glioblastoma | completed | N/A | 29 | OHSU Knight Cancer InstituteOTHER | 1 | Mar 17, 2022 | clinicaltrials |
| NCT04516733 | Precoce Medical Care by the Mobil Support for Patients With Glioblastoma(GLIOSUPPORT) | completed | N/A | 35 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Mar 14, 2022 | clinicaltrials |
| NCT01891747 | A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma | completed | Phase 1 | 14 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Mar 10, 2022 | clinicaltrials |
| NCT02270034 | Study to Evaluate Safety and Activity of Crizotinib With Temozolomide and Radiotherapy in Newly Diagnosed Glioblastoma | completed | Phase 1 | 38 | Grupo Español de Investigación en NeurooncologíaOTHER | 1 | Mar 10, 2022 | clinicaltrials |
| NCT02526017 | Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers(FPA008-003) | completed | Phase 1 | 313 | Five Prime Therapeutics, Inc.INDUSTRY | 1 | Mar 9, 2022 | clinicaltrials |
| NCT02013297 | Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics)(SBRT) | completed | N/A | 61 | Centre Leon BerardOTHER | 1 | Mar 8, 2022 | clinicaltrials |
| NCT03566199 | MTX110 by Convection-Enhanced Delivery in Treating Participants With Newly-Diagnosed Diffuse Intrinsic Pontine Glioma(PNOC015) | completed | Phase 1 / Phase 2 | 7 | Sabine Mueller, MD, PhDOTHER | 1 | Feb 25, 2022 | clinicaltrials |
| NCT02731521 | Clinical Development of MR Spectroscopy and Imaging in Brain Cancers | completed | — | 112 | University of Texas Southwestern Medical CenterOTHER | 1 | Feb 3, 2022 | clinicaltrials |
| NCT00967577 | 177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors | completed | Phase 1 | 20 | Weill Medical College of Cornell UniversityOTHER | 1 | Feb 2, 2022 | clinicaltrials |
| NCT02343224 | Pegylated Interferon ALFA-2b in Children With Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas | completed | Phase 2 | 9 | Emory UniversityOTHER | 1 | Jan 24, 2022 | clinicaltrials |
| NCT03341806 | Avelumab With Laser Interstitial Therapy for Recurrent Glioblastoma | completed | Phase 1 | 13 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Jan 4, 2022 | clinicaltrials |
| NCT01222754 | Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas | completed | Phase 1 | 29 | National Cancer Institute (NCI)NIH | 1 | Jan 3, 2022 | clinicaltrials |
| NCT03990285 | [18F]Fluciclovine in Post-treatment Glioblastoma ( Axumin )(Axumin) | completed | Phase 1 | 30 | Ali NabavizadehOTHER | 1 | Dec 22, 2021 | clinicaltrials |
| NCT02892708 | Impact of Surgery on the Treatment of Supratentorial Malignant Gliomas in Subjects Aged 70 and Over(CSA) | completed | Phase 3 | 107 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Dec 9, 2021 | clinicaltrials |
| NCT00805961 | RT, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in First-line Treatment of GBM | completed | Phase 2 | 68 | SCRI Development Innovations, LLCOTHER | 1 | Dec 8, 2021 | clinicaltrials |
| NCT01856933 | BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM) | completed | Phase 2 | 6 | Heinrich Elinzano, MDOTHER | 1 | Nov 23, 2021 | clinicaltrials |
| NCT02010606 | Phase I Study of a Dendritic Cell Vaccine for Patients With Either Newly Diagnosed or Recurrent Glioblastoma | completed | Phase 1 | 39 | Cedars-Sinai Medical CenterOTHER | 1 | Nov 22, 2021 | clinicaltrials |
| NCT05100173 | Clinical Evaluation of Genetron IDH1 PCR Kit in Glioma Patients | completed | — | 1,192 | Genetron HealthINDUSTRY | 1 | Nov 22, 2021 | clinicaltrials |
| NCT05100602 | Clinical Evaluation of Genetron TERT PCR Kit in Glioma Patients | completed | — | 1,192 | Genetron HealthINDUSTRY | 1 | Nov 22, 2021 | clinicaltrials |
| NCT03291990 | 5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme | completed | Early Phase 1 | 3 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Nov 19, 2021 | clinicaltrials |
| NCT03374943 | A Trial of KB004 in Patients With Glioblastoma | completed | Phase 1 | 12 | Olivia Newton-John Cancer Research InstituteOTHER | 1 | Nov 4, 2021 | clinicaltrials |
| NCT02747407 | Qualitative, Qualitative, and Functional Studies Over the First Year in Measuring Immune System Response During the First Year of Therapy in Patients With Brain Tumors | completed | — | 55 | Wake Forest University Health SciencesOTHER | 1 | Oct 29, 2021 | clinicaltrials |
| NCT01189266 | Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma | completed | Phase 1 / Phase 2 | 79 | National Cancer Institute (NCI)NIH | 3 | Oct 28, 2021 | clinicaltrials |
| NCT02379572 | Impact of iMRI on the Extent of Resection in Patients With Newly Diagnosed Glioblastomas | completed | N/A | 315 | University Hospital TuebingenOTHER | 1 | Oct 22, 2021 | clinicaltrials |
| NCT02015819 | Genetically Modified Neural Stem Cells, Flucytosine, and Leucovorin for Treating Patients With Recurrent High-Grade Gliomas | completed | Phase 1 | 16 | City of Hope Medical CenterOTHER | 1 | Oct 20, 2021 | clinicaltrials |
| NCT01479686 | iMRI Guided Resection in Cerebral Glioma Surgery | completed | Phase 3 | 321 | Huashan HospitalOTHER | 1 | Oct 19, 2021 | clinicaltrials |
| NCT00112502 | Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patients Who Have Undergone Radiation Therapy for Glioblastoma Multiforme | completed | Phase 2 | 178 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 18, 2021 | clinicaltrials |
| NCT02919865 | MR Perfusion Methods in Patients With Suspected Recurrent High Grade Gliomas | completed | N/A | 50 | Ottawa Hospital Research InstituteOTHER | 1 | Oct 8, 2021 | clinicaltrials |
| NCT01353625 | Study to Assess Safety and Tolerability of Oral CC-115 for Patients With Advanced Solid Tumors, and Hematologic Malignancies. | completed | Phase 1 | 118 | CelgeneINDUSTRY | 4 | Oct 5, 2021 | clinicaltrials |
| NCT02770378 | A Proof-of-concept Clinical Trial Assessing the Safety of the Coordinated Undermining of Survival Paths by 9 Repurposed Drugs Combined With Metronomic Temozolomide (CUSP9v3 Treatment Protocol) for Recurrent Glioblastoma | completed | Phase 1 / Phase 2 | 10 | University of UlmOTHER | 1 | Oct 5, 2021 | clinicaltrials |
| NCT03212157 | GlucoCEST MRI in Oncology | completed | N/A | 15 | University College, LondonOTHER | 1 | Sep 29, 2021 | clinicaltrials |
| NCT02844439 | Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma | completed | Phase 2 | 40 | Kadmon Corporation, LLCINDUSTRY | 1 | Sep 22, 2021 | clinicaltrials |
| NCT03034135 | Safety, Tolerability and Efficacy of Disulfiram and Copper Gluconate in Recurrent Glioblastoma | completed | Phase 2 | 23 | Cantex PharmaceuticalsINDUSTRY | 1 | Sep 13, 2021 | clinicaltrials |
| NCT03243851 | Study on Low Dose Temozolomide Plus Metformin or Placebo in Patient With Recurrent or Refractory Glioblastoma(METT) | completed | Phase 2 | 81 | Yong-Kil HongOTHER | 1 | Sep 9, 2021 | clinicaltrials |
Data updated 23 days agoSource updated May 27, 2022source: clinicaltrials