Clinical trial · Interventional
Exercise in Patients With Glioblastoma
Does Exercise Improve Progression-free Survival in Glioblastoma? A Prospective Single Arm Intervention Trial
NCT03390569CI-TRIAL-00057801completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Patients with newly-diagnosed GBM will be given personalized exercise regimes during concurrent chemo-radiation and up to 3 months later. Study aims are to investigate the feasibility and preliminary efficacy of the exercise program on progression free survival. Secondary outcomes of interest include cognition, fatigue, and quality of life.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Glioblastoma | Glioblastoma | CURATED_BROADER | 0.80 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Exercise in GBM
- description
- All patients will be assigned a three-month exercise intervention according to their own capabilities and current activity levels
- interventionNames
- Behavioral: Exercise
Primary outcomes (1)
- measure
- Progression-Free Survival
- timeFrame
- 6 months
- description
- Time to tumor progression, based on Response Assessment in Neuro-Oncology (RANO) criteria
Secondary outcomes (9)
- measure
- Cognitive Decline
- timeFrame
- 3 months, 6 months, 12 months, 18 months post-treatment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * newly diagnosed glioblastoma * fluent in English * scheduled to be treated with concurrent chemoradiation (or within 2 weeks of starting treatment) Exclusion Criteria: * brain metastases secondary to non-central nervous system cancer * less than 18 years old * receiving treatment at a location other than the Princess Margaret Cancer Centre * deemed unfit to exercise by a study oncologist * lack of fluency in English * psychiatric or neurological disorders that could interfere with participation
References
Publications (0)
Data not yet available
No reference posted for this study.