Subtype
Colorectal Neoplasm
CI-CAN-00002404Explore in graph →
Non-malignant1,784 active trials21 approved drugs382 evidence items
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Subtype
CI-CAN-00002404Explore in graph →
Clinical trials
8,604 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02273167 | Multicenter Randomized Parallel Group Phase III Study Comparing the Bowel Cleansing Efficacy, Safety and Tolerability of NER1006 Versus MOVIPREP® Using 2-Day Split-Dosing and 1-Day Morning Split-Dosing Regimen in Adults.(MORA) | completed | Phase 3 | 849 | NorgineINDUSTRY | 7 | May 15, 2018 | clinicaltrials |
| NCT02706184 | E. Coli Nissle in Oncology(EcNO) | completed | Phase 3 | 20 | University of HohenheimOTHER | 1 | May 15, 2018 |
| clinicaltrials |
| NCT03177382 | Total Neoadjuvant Treatment vs. Chemoradiotherapy in Local Advanced Rectal Cancer With High Risk Factors(TNTCRT) | unknown | Phase 3 | 458 | West China HospitalOTHER | 1 | May 8, 2018 | clinicaltrials |
| NCT02284139 | Pilot Trial of EGF Ointment for the Patients With EGFR-i Related Skin Side Effects | completed | Phase 2 / Phase 3 | 90 | Dong-A University HospitalOTHER | 1 | Apr 23, 2018 | clinicaltrials |
| NCT00758186 | Randomized Trial of Colonic Stents as a Bridge to Surgery | completed | Phase 3 | 40 | Singapore General HospitalOTHER | 1 | Apr 18, 2018 | clinicaltrials |
| NCT02907385 | Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing | unknown | Phase 3 | 736 | LifeBond Ltd.INDUSTRY | 7 | Mar 30, 2018 | clinicaltrials |
| NCT00427375 | Local Excision in Downstaged Rectal Cancer(GRECCAR 2) | completed | Phase 3 | 148 | University Hospital, BordeauxOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT01918852 | S-1 Versus Capecitabine in the First Line Treatment of MCC Patients.(SALTO) | completed | Phase 3 | 161 | Dutch Colorectal Cancer GroupOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT01196260 | Combination Chemotherapy Treatments in Patients With Colorectal Cancer Stage II and III | unknown | Phase 2 / Phase 3 | 8,000 | State Key Laboratory of Cancer BiologyNETWORK | 1 | Feb 20, 2018 | clinicaltrials |
| NCT03431428 | Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients | unknown | Phase 3 | 477 | Zhang RuiOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT03428529 | Capecitabine Versus Bolus 5-Fu Associated to Radiotherapy as Neoadjuvant Treatment for Rectal Cancer.(INCAGI004) | completed | Phase 2 / Phase 3 | 63 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 0 | Feb 9, 2018 | clinicaltrials |
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT00911170 | PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study | completed | Phase 3 | 847 | AmgenINDUSTRY | 17 | Dec 29, 2017 | clinicaltrials |
| NCT01279681 | Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer | terminated | Phase 3 | 32 | Alliance for Clinical Trials in OncologyOTHER | 0 | Dec 8, 2017 | clinicaltrials |
| NCT03362684 | PETACC-8 miR-31-3p and miR-31-5p Ancillary Study | completed | Phase 3 | 1,808 | IntegraGen SAINDUSTRY | 0 | Dec 5, 2017 | clinicaltrials |
| NCT01694966 | The Safety and Efficacy of Methylene Blue MMX® Modified Release Tablets Administered to Subjects Undergoing Screening or Surveillance Colonoscopy | completed | Phase 3 | 1,249 | Cosmo Technologies LtdINDUSTRY | 8 | Nov 6, 2017 | clinicaltrials |
| NCT01939223 | Colorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudy(COAST) | terminated | Phase 3 | 25 | BayerINDUSTRY | 14 | Oct 20, 2017 | clinicaltrials |
| NCT01308086 | Adjuvant Therapy(3 vs. 6 Months) With the FOLFOX 4 or XELOX for Stage II or Stage III Colon Cancer | unknown | Phase 3 | 2,000 | Hellenic Oncology Research GroupOTHER | 1 | Aug 9, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT02149108 | Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1) | completed | Phase 3 | 768 | Boehringer IngelheimINDUSTRY | 25 | Jul 21, 2017 | clinicaltrials |
| NCT03221608 | Clinical Analysis of HIPEC for T4 Colorectal Cancer After Surgery | unknown | Phase 3 | 300 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Jul 18, 2017 | clinicaltrials |
| NCT01309126 | Study of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal Cancer(PRIMUS) | terminated | Phase 3 | 217 | HiberCell, Inc.INDUSTRY | 4 | Jul 13, 2017 | clinicaltrials |
| NCT01895257 | Comparing HAI-90Y (SIR-spheres)+Chemotx LV5FU2 Versus Chemotx LV5FU2 Alone to Treat Colorectal Cancer | unknown | Phase 3 | 162 | Universiteit AntwerpenOTHER | 1 | Jul 7, 2017 | clinicaltrials |
| NCT00883792 | The Northern-European Initiative on Colorectal Cancer(NordICC) | active not recruiting | Phase 3 | 95,000 | Oslo University HospitalOTHER | 6 | Jun 19, 2017 | clinicaltrials |
| NCT00687830 | Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.(CCF) | completed | Phase 3 | 136 | Cleveland Clinic FloridaOTHER | 1 | May 17, 2017 | clinicaltrials |
| NCT01646554 | Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases(BOS3) | withdrawn | Phase 2 / Phase 3 | 0 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | May 9, 2017 | clinicaltrials |
| NCT02060669 | Xeloda Maintenance Versus BSC in Metastatic Colorectal Cancer | terminated | Phase 3 | 10 | Samsung Medical CenterOTHER | 1 | Apr 27, 2017 | clinicaltrials |
| NCT03125161 | Study Comparing HAI Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM | unknown | Phase 3 | 150 | Fudan UniversityOTHER | 1 | Apr 24, 2017 | clinicaltrials |
| NCT03125980 | Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer | recruiting | Phase 3 | 1,370 | Fudan UniversityOTHER | 1 | Apr 24, 2017 | clinicaltrials |
| NCT00509444 | Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial(CPTD) | completed | Phase 3 | 200 | Johns Hopkins Bloomberg School of Public HealthOTHER | 1 | Apr 20, 2017 | clinicaltrials |
| NCT00384176 | First Line Metastatic Colorectal Cancer Therapy in Combination With FOLFOX(HORIZON III) | completed | Phase 2 / Phase 3 | 1,814 | AstraZenecaINDUSTRY | 28 | Apr 14, 2017 | clinicaltrials |
| NCT01523431 | Individual Dosage Selection of Irinotecan (CPT-11) Based on UGT1A1 Genotype in Metastatic Colorectal Cancer Patients | completed | Phase 2 / Phase 3 | 583 | The Affiliated Hospital of the Chinese Academy of Military Medical SciencesOTHER | 1 | Mar 30, 2017 | clinicaltrials |
| NCT00153816 | Vitamin D/Calcium Polyp Prevention Study | completed | Phase 2 / Phase 3 | 2,813 | Dartmouth-Hitchcock Medical CenterOTHER | 2 | Mar 15, 2017 | clinicaltrials |
| NCT01412957 | Comparison of Survival Benefit of Panitumumab With Supportive Care to Best Supportive Care Alone in Patients With Metastatic Colorectal Cancer | completed | Phase 3 | 377 | AmgenINDUSTRY | 16 | Mar 15, 2017 | clinicaltrials |
| NCT00056446 | Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer | completed | Phase 3 | 855 | Novartis PharmaceuticalsINDUSTRY | 18 | Mar 6, 2017 | clinicaltrials |
| NCT03038217 | Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer | unknown | Phase 3 | 300 | Peking Union Medical College HospitalOTHER | 0 | Feb 3, 2017 | clinicaltrials |
| NCT01786694 | Feasibility of Microdialysis by Laparoscopy(MTM-COLON-I) | completed | Phase 3 | 11 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Feb 1, 2017 | clinicaltrials |
| NCT00154102 | Cetuximab Combined With Irinotecan in First-line Therapy for Metastatic Colorectal Cancer (CRYSTAL)(CRYSTAL) | completed | Phase 3 | 1,221 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 30 | Jan 30, 2017 | clinicaltrials |
| NCT00399035 | Cediranib (AZD2171, RECENTIN™) in Addition to Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer(HORIZON II) | completed | Phase 3 | 1,254 | AstraZenecaINDUSTRY | 15 | Dec 28, 2016 | clinicaltrials |
| NCT01169558 | A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum. | completed | Phase 3 | 168 | Hoffmann-La RocheINDUSTRY | 1 | Dec 8, 2016 | clinicaltrials |
| NCT02978313 | Cetuximab Monotherapy Maintenance Treatment in mCRC | unknown | Phase 2 / Phase 3 | 500 | Ruijin HospitalOTHER | 0 | Nov 30, 2016 | clinicaltrials |
| NCT02208804 | Surefire Infusion System vs. Standard Microcatheter Use During Holmium-166 Radioembolization(SIM) | unknown | Phase 2 / Phase 3 | 25 | UMC UtrechtOTHER | 1 | Nov 9, 2016 | clinicaltrials |
| NCT01338558 | A Study of Avastin (Bevacizumab) in Combination With mFOLFOX6 in Treatment-Naïve Patients With Metastatic Colorectal Cancer With or Without K-RAS Mutations, and Comparison to Cetuximab | withdrawn | Phase 3 | 0 | Hoffmann-La RocheINDUSTRY | 0 | Nov 2, 2016 | clinicaltrials |
| NCT02935764 | FOLFIRI Versus Irinotecan as Second-line Treatment in Metastatic Colorectal Cancer Patients | unknown | Phase 3 | 164 | Fudan UniversityOTHER | 0 | Oct 17, 2016 | clinicaltrials |
| NCT00766155 | Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer(PETACC-6) | completed | Phase 3 | 1,094 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 0 | Oct 12, 2016 | clinicaltrials |
| NCT02266849 | Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study | terminated | Phase 3 | 12 | Odense University HospitalOTHER | 1 | Oct 11, 2016 | clinicaltrials |
| NCT01372007 | Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma | completed | Phase 3 | 24 | University Hospital, GhentOTHER | 1 | Oct 7, 2016 | clinicaltrials |
| NCT00069095 | A Study of Capecitabine (Xeloda) and Bevacizumab as a First-line Therapy in Patients With Metastatic Colorectal Cancer | completed | Phase 3 | 2,035 | Hoffmann-La RocheINDUSTRY | 33 | Oct 6, 2016 | clinicaltrials |
| NCT00392899 | Tegafur-Uracil or Observation in Treating Patients With Stage II Colorectal Cancer That Has Been Completely Removed By Surgery | completed | Phase 3 | 2,025 | Translational Research Center for Medical Innovation, Kobe, Hyogo, JapanOTHER | 1 | Sep 28, 2016 | clinicaltrials |
| NCT02912052 | Perioperative Chemotherapy VS Postoperative Chemotherapy for the Treatment of Colon Cancer With Resectable Liver Metastasis(PEPCORLI) | unknown | Phase 3 | 240 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 1 | Sep 23, 2016 | clinicaltrials |
Data updated 23 days agoSource updated May 15, 2018source: clinicaltrials