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CancerIndexthe global index of cancer

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

Cancers Data Trials Drugs Genes Biomarkers Approvals Rankings Research gap Graph

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CancerIndex

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Colorectal Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Digestive System Neoplasm
Intestinal Neoplasm
Large Intestinal Neoplasm
Colorectal Neoplasm

Subtype

Colorectal Neoplasm

CI-CAN-00002404Explore in graph →

Non-malignant1,783 active trials21 approved drugs382 evidence items

NCIt: C2956
MeSH: D015179

Overview
Statistics
Survival
Genomics27
Variants & evidence382
Drugs79
Trials8601
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (357)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 326–350 of 357 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors.
· Cell Cycle · 2012 · PMID 22262166 · validated civic_curation pubmed
Toll-like receptor 9 agonist IMO cooperates with cetuximab in K-ras mutant colorectal and pancreatic cancers.
· Clin Cancer Res · 2011 · PMID 21890455 · validated civic_curation pubmed
OCT4B1 promotes cell growth, migration and invasion suppressing sensitivity to οxaliplatin in colon cancer.
· Oncol Rep · 2015 · PMID 26398480 · validated civic_curation pubmed
NTRK1 fusions for the therapeutic intervention of Korean patients with colon cancer.
· Oncotarget · 2016 · PMID 26716414 · validated civic_curation pubmed
KRAS exon 2 mutations influence activity of regorafenib in an SW48-based disease model of colorectal cancer.
· Future Oncol · 2015 · PMID 26161928 · validated civic_curation pubmed
Exome Sequencing of Plasma DNA Portrays the Mutation Landscape of Colorectal Cancer and Discovers Mutated VEGFR2 Receptors as Modulators of Antiangiogenic Therapies.
· Clin Cancer Res · 2018 · PMID 29588308 · validated civic_curation pubmed
KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.
· PLoS One · 2015 · PMID 26709701 · validated

Showing 326–350 of 357 publications

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civic_curation

BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation.

· Sci Signal · 2010 · PMID 21098728 · validated civic_curation pubmed

ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers.

· Mol Cancer Res · 2014 · PMID 24296758 · validated civic_curation pubmed

Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer.

· Cancer Discov · 2018 · PMID 29196463 · validated civic_curation pubmed

Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers.

· Mol Cancer Res · 2009 · PMID 19737969 · validated civic_curation pubmed

Guda et al. PNAS 2015

· 2015 · PMID 25583493 · validated cbioportal_study pubmed

Vasaikar et al. Cell 2019

· 2019 · PMID 31031003 · validated cbioportal_study pubmed

Roelands et al, Nat Med 2023

· 2023 · PMID 37202560 · validated cbioportal_study pubmed

Li et al. Cancer Cell 2020

· 2020 · PMID 32888432 · validated cbioportal_study pubmed

Giannakis et al. Cell Reports 2016

· 2016 · PMID 27149842 · validated cbioportal_study pubmed

Seshagiri et al. Nature 2012

· 2012 · PMID 22895193 · validated cbioportal_study pubmed

Brannon et al. Genome Biol 2014

· 2014 · PMID 25164765 · validated cbioportal_study pubmed

Yaeger et al. Cancer Discovery 2022

· 2022 · PMID 36355783 · validated cbioportal_study pubmed

TCGA, Nature 2012

· 2012 · PMID 22810696 · validated cbioportal_study pubmed

Mondaca et al. Gastroenterology 2020

· 2020 · PMID 32730818 · validated cbioportal_study pubmed

Gularte-Merida et al. JCO Precis Oncol 2022

· 2022 · PMID 35235413 · validated cbioportal_study pubmed

Chen et al. Cell 2021

· 2021 · PMID 34910928 · validated cbioportal_study pubmed

Moorman et al. Nature 2025

· 2025 · PMID 39478232 · validated cbioportal_study pubmed

Yaeger et al. Cancer Cell 2018

· 2018 · PMID 29316426 · validated cbioportal_study pubmed