Subtype
Cholangiocarcinoma
CI-CAN-00004932CCExplore in graph →
210 active trials3 approved drugs29 evidence items
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Subtype
CI-CAN-00004932CCExplore in graph →
Genomics
14 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
35 cases with simple somatic mutation data · 51 cases total · 2026-01-06 · mapped to Cholangiocarcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | MUC4 | Ssm | 14 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 35 |
| 40% |
| cbioportal |
| 2 | TTN | Ssm | 10 | 35 | 28.6% | cbioportal |
| 4 | PBRM1 | Ssm | 8 | 35 | 22.9% | cbioportal |
| 3 | BAP1 | Ssm | 8 | 35 | 22.9% | cbioportal |
| 8 | MUC2 | Ssm | 7 | 35 | 20% | cbioportal |
| 7 | KMT2C | Ssm | 7 | 35 | 20% | cbioportal |
| 6 | CDC27 | Ssm | 7 | 35 | 20% | cbioportal |
| 5 | ANKRD36C | Ssm | 7 | 35 | 20% | cbioportal |
| 10 | MUC5B | Ssm | 6 | 35 | 17.1% | cbioportal |
| 11 | TCHH | Ssm | 6 | 35 | 17.1% | cbioportal |
| 9 | DNAH5 | Ssm | 6 | 35 | 17.1% | cbioportal |
| 22 | POLE | Ssm | 5 | 35 | 14.3% | cbioportal |
| 12 | ABCA13 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 18 | BLTP1 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 17 | BIRC6 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 21 | PLXNA4 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 13 | ADGRV1 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 14 | AHNAK | Ssm | 5 | 35 | 14.3% | cbioportal |
| 24 | TP53 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 20 | MUC16 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 23 | RYR3 | Ssm | 5 | 35 | 14.3% | cbioportal |
| 19 | HLA-B | Ssm | 5 | 35 | 14.3% | cbioportal |
| 15 | ARID1A | Ssm | 5 | 35 | 14.3% | cbioportal |
| 16 | ATM | Ssm | 5 | 35 | 14.3% | cbioportal |
| 25 | AHNAK2 | Ssm | 4 | 35 | 11.4% | cbioportal |
| 32 | DMXL2 | Ssm | 4 | 35 | 11.4% | cbioportal |
| 35 | FAT1 | Ssm | 4 | 35 | 11.4% | cbioportal |
| 51 | PRG4 | Ssm | 4 | 35 | 11.4% | cbioportal |
| 52 | PTH2 | Ssm | 4 | 35 | 11.4% | cbioportal |
| 53 | RAD54L2 | Ssm | 4 | 35 | 11.4% | cbioportal |
Data updated 22 days agoSource updated 2026-01-06