Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01480479 | Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma(ACT IV) | completed | Phase 3 | 745 | Celldex TherapeuticsINDUSTRY | 24 | Jan 16, 2018 | clinicaltrials |
| NCT01759810 | Proteome-based Personalized Immunotherapy of Glioblastoma | unknown | Phase 2 / Phase 3 | 60 | NeuroVita ClinicOTHER | 1 | Oct 12, 2017 | clinicaltrials |
| NCT00943826 |
| A Study of Bevacizumab (Avastin®) in Combination With Temozolomide and Radiotherapy in Participants With Newly Diagnosed Glioblastoma |
| completed |
| Phase 3 |
| 921 |
| Hoffmann-La RocheINDUSTRY |
| 24 |
| Sep 25, 2017 |
| clinicaltrials |
| NCT03271918 | Cabergoline in Nonfunctioning Pituitary Adenomas | completed | Phase 3 | 140 | University of Sao Paulo General HospitalOTHER | 1 | Sep 7, 2017 | clinicaltrials |
| NCT00522951 | SH L 562BB Phase II/III Dose Justification and Gadoteridol-controlled Comparative Study | completed | Phase 3 | 165 | BayerINDUSTRY | 1 | Aug 28, 2017 | clinicaltrials |
| NCT02563288 | Esmolol Versus Dexmedetomidine During Intracranial Procedures | unknown | Phase 3 | 60 | George Papanicolaou HospitalOTHER | 1 | Jul 27, 2017 | clinicaltrials |
| NCT01260103 | Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma | withdrawn | Phase 3 | 0 | Burzynski Research InstituteOTHER | 0 | Jul 26, 2017 | clinicaltrials |
| NCT01149109 | Efficacy and Safety Study of Lomustine/Temozolomide Combination Therapy vs. Standard Therapy for Glioblastoma Patients(CeTeG) | completed | Phase 3 | 141 | University Hospital, BonnOTHER | 1 | Jun 14, 2017 | clinicaltrials |
| NCT00335075 | Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644) | completed | Phase 3 | 151 | Merck Sharp & Dohme LLCINDUSTRY | 0 | May 15, 2017 | clinicaltrials |
| NCT00916409 | Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM) | completed | Phase 3 | 700 | NovoCure Ltd.INDUSTRY | 12 | Apr 10, 2017 | clinicaltrials |
| NCT01724801 | Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer(BRAIN) | completed | Phase 3 | 176 | Guangdong Association of Clinical TrialsOTHER | 1 | Mar 1, 2017 | clinicaltrials |
| NCT00777153 | Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma(REGAL) | completed | Phase 3 | 423 | AstraZenecaINDUSTRY | 10 | Dec 28, 2016 | clinicaltrials |
| NCT01961934 | C11-Sodium Acetate PET/CT Imaging Evaluation in Brain Glioma, Post Therapy Necrosis and Pseudo-progression | withdrawn | Phase 2 / Phase 3 | 0 | Phoenix Molecular ImagingOTHER | 1 | Sep 28, 2016 | clinicaltrials |
| NCT00088400 | Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors | completed | Phase 3 | 30 | National Institute of Neurological Disorders and Stroke (NINDS)NIH | 1 | Sep 22, 2016 | clinicaltrials |
| NCT00280475 | A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis | completed | Phase 3 | 270 | Haruhiko FukudaOTHER | 1 | Sep 22, 2016 | clinicaltrials |
| NCT02363075 | Dexamfetamine Sulphate in Patients With Glioma Suffering From Severe Asthenia(DXA) | unknown | Phase 3 | 58 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Sep 15, 2016 | clinicaltrials |
| NCT01620138 | Response to Cabergoline and Pasireotide in Non-functioning Pituitary Adenomas and Resistant Prolactinomas | completed | Phase 2 / Phase 3 | 21 | Universidade Federal do Rio de JaneiroOTHER | 1 | Aug 22, 2016 | clinicaltrials |
| NCT02636634 | Non Invasive Methods for Differential Diagnosis Radionecrosis/Recurrence After Radiosurgery of Brain Metastases(CV-METANEC) | completed | Phase 3 | 90 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Apr 11, 2016 | clinicaltrials |
| NCT01830101 | A Phase III Study of Re-Irradiation in Recurrent Glioblastoma | withdrawn | Phase 3 | 0 | AHS Cancer Control AlbertaOTHER | 1 | Mar 16, 2016 | clinicaltrials |
| NCT00123760 | Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Cancer or Suspected Cancer | completed | Phase 2 / Phase 3 | 10,838 | AHS Cancer Control AlbertaOTHER | 1 | Feb 25, 2016 | clinicaltrials |
| NCT01364064 | Conventional Adjuvant Temozolomide With Dose Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma | completed | Phase 3 | 1,153 | King Faisal Specialist Hospital & Research CenterOTHER | 0 | Feb 25, 2016 | clinicaltrials |
| NCT00789828 | Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)(EXIST-1) | completed | Phase 3 | 117 | Novartis PharmaceuticalsINDUSTRY | 10 | Feb 3, 2016 | clinicaltrials |
| NCT02623231 | The Effect of Escitalopram on Mood, Quality of Life and Cognitive Functioning in Glioblastoma Patients(Cipralex&GBM) | unknown | Phase 2 / Phase 3 | 100 | Tel-Aviv Sourasky Medical CenterOTHER_GOV | 1 | Dec 7, 2015 | clinicaltrials |
| NCT02460068 | A Study of Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis(NIBIT-M2) | unknown | Phase 3 | 168 | Italian Network for Tumor Biotherapy FoundationOTHER | 1 | Jun 2, 2015 | clinicaltrials |
| NCT01450449 | Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme | completed | Phase 3 | 115 | International Atomic Energy AgencyOTHER_GOV | 14 | Mar 24, 2015 | clinicaltrials |
| NCT02338011 | Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases)(EGFR) | unknown | Phase 2 / Phase 3 | 210 | Shanghai Chest HospitalOTHER | 1 | Jan 26, 2015 | clinicaltrials |
| NCT02137928 | Carboplatin Periocular Injection for Retinoblastoma | unknown | Phase 3 | 50 | Sun Yat-sen UniversityOTHER | 1 | Dec 19, 2014 | clinicaltrials |
| NCT00681551 | Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis | completed | Phase 3 | 45 | BayerINDUSTRY | 1 | Dec 15, 2014 | clinicaltrials |
| NCT00761280 | Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma(SAPPHIRE) | terminated | Phase 3 | 27 | Isarna Therapeutics GmbHINDUSTRY | 16 | Nov 14, 2014 | clinicaltrials |
| NCT00689221 | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status(CENTRIC) | completed | Phase 3 | 545 | EMD SeronoINDUSTRY | 2 | Nov 4, 2014 | clinicaltrials |
| NCT00088166 | XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors | completed | Phase 3 | 200 | Celtic Pharma Development ServicesINDUSTRY | 2 | Aug 13, 2014 | clinicaltrials |
| NCT00897377 | Treatment Strategy for Low-grade Gliomas | terminated | Phase 3 | 500 | Sun Yat-sen UniversityOTHER | 1 | Aug 5, 2014 | clinicaltrials |
| NCT00002875 | Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma | completed | Phase 3 | 421 | Children's Oncology GroupNETWORK | 5 | Aug 1, 2014 | clinicaltrials |
| NCT00053872 | Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma | unknown | Phase 3 | 316 | University of LeicesterOTHER | 8 | Jun 24, 2014 | clinicaltrials |
| NCT01169129 | Surgery and Whole Brain Radiotherapy (RT) Versus Whole Brain Radiotherapy (RT) and Radiosurgery for 1-3 Resectable Brain Metastases | withdrawn | Phase 3 | 0 | Barretos Cancer HospitalOTHER | 1 | Feb 4, 2014 | clinicaltrials |
| NCT01460706 | Imaging Malignant Glioma With 68Ga-DOTATOC PET/CT(DOTAGLI) | completed | Phase 2 / Phase 3 | 30 | Turku University HospitalOTHER_GOV | 1 | Dec 12, 2013 | clinicaltrials |
| NCT00003859 | Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS | completed | Phase 3 | 230 | Societe Internationale d'Oncologie PediatriqueOTHER | 1 | Dec 4, 2013 | clinicaltrials |
| NCT00293358 | Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain | completed | Phase 3 | 500 | Children's Cancer and Leukaemia GroupOTHER | 2 | Sep 17, 2013 | clinicaltrials |
| NCT00002944 | Combination Chemotherapy in Treating Children With Progressive Brain Tumors | completed | Phase 3 | 428 | Children's Oncology GroupNETWORK | 6 | Sep 9, 2013 | clinicaltrials |
| NCT00006461 | Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor | completed | Phase 3 | 82 | Children's Oncology GroupNETWORK | 1 | Aug 9, 2013 | clinicaltrials |
| NCT00517959 | SCRT Versus Conventional RT in Children and Young Adults With Low Grade and Benign Brain Tumors(SCRT) | unknown | Phase 3 | 200 | Tata Memorial HospitalOTHER_GOV | 1 | Dec 11, 2012 | clinicaltrials |
| NCT00104936 | Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign Meningioma That Has Been Partially Removed by Surgery | terminated | Phase 3 | 9 | European Organisation for Research and Treatment of Cancer - EORTCNETWORK | 3 | Sep 24, 2012 | clinicaltrials |
| NCT00226655 | An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies | completed | Phase 3 | 112 | Celtic Pharma Development ServicesINDUSTRY | 2 | Aug 31, 2012 | clinicaltrials |
| NCT01656980 | Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Newly Diagnosed Malignant Glioma | unknown | Phase 3 | 236 | Shandong Lanjin Pharmaceuticals Co.,LtdINDUSTRY | 1 | Aug 3, 2012 | clinicaltrials |
| NCT01655927 | Efficacy of Tranexamic Acid in Brain Tumor Resections(COLFIRE) | unknown | Phase 3 | 100 | Colombian Foundation for Epilepsy and Neurological DiseaseOTHER | 1 | Aug 2, 2012 | clinicaltrials |
| NCT00389883 | Anaesthesia for Supratentorial Tumor Resection | completed | Phase 3 | 69 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jul 10, 2012 | clinicaltrials |
| NCT01635140 | Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children | completed | Phase 3 | 64 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Jul 9, 2012 | clinicaltrials |
| NCT00379470 | Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM) | completed | Phase 3 | 236 | NovoCure Ltd.INDUSTRY | 7 | May 1, 2012 | clinicaltrials |
| NCT01167322 | Study of NPC-07 for Fluorescence-guided Resection of Malignant Gliomas | completed | Phase 3 | 45 | NobelpharmaINDUSTRY | 1 | Apr 27, 2012 | clinicaltrials |
Data updated 23 days agoSource updated Jan 16, 2018source: clinicaltrials