Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03347097 | Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme | unknown | Early Phase 1 | 40 | Huashan HospitalOTHER | 1 | Aug 25, 2021 | clinicaltrials |
| NCT03930173 | 18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis | completed | Early Phase 1 | 18 | Case Comprehensive Cancer CenterOTHER | 1 | May 5, 2021 | clinicaltrials |
| NCT03980249 |
| Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells |
| withdrawn |
| Early Phase 1 |
| 0 |
| West Virginia UniversityOTHER |
| 1 |
| Apr 12, 2021 |
| clinicaltrials |
| NCT02630030 | Phase 0 Analysis of Ixazomib (MLN9708) in Patients With Glioblastoma | completed | Early Phase 1 | 3 | Emory UniversityOTHER | 1 | Mar 26, 2021 | clinicaltrials |
| NCT03001349 | 68Ga-DOTA-TOC PET/CT in Imaging Participants With Neuroendocrine Tumors | terminated | Early Phase 1 | 4 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 15, 2021 | clinicaltrials |
| NCT02605746 | Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis | completed | Early Phase 1 | 10 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Dec 11, 2020 | clinicaltrials |
| NCT02207010 | A Phase 0 Study of AZD1775 in Recurrent GBM Patients | completed | Early Phase 1 | 20 | St. Joseph's Hospital and Medical Center, PhoenixOTHER | 1 | Dec 10, 2020 | clinicaltrials |
| NCT03151772 | Bioavailability of Disulfiram and Metformin in Glioblastomas(INSIDE) | terminated | Early Phase 1 | 3 | Sahlgrenska University HospitalOTHER | 1 | Sep 28, 2020 | clinicaltrials |
| NCT01466855 | A Study of Intra-Ophthalmic Artery Topotecan Infusion for the Treatment of Retinoblastoma(IARB1) | terminated | Early Phase 1 | 36 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | Sep 14, 2020 | clinicaltrials |
| NCT04220892 | Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma | withdrawn | Early Phase 1 | 0 | Jose CarrilloOTHER | 1 | Jul 31, 2020 | clinicaltrials |
| NCT02507232 | Study of NovoTTF-200A Alone and With Temozolomide in Patients With Low-Grade Gliomas | terminated | Early Phase 1 | 2 | Santosh KesariOTHER | 1 | Jul 28, 2020 | clinicaltrials |
| NCT04417933 | Tumor Electric Fields Treatment System for Glioblastoma | unknown | Early Phase 1 | 5 | Xiangya Hospital of Central South UniversityOTHER | 1 | Jun 11, 2020 | clinicaltrials |
| NCT01880749 | Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas | completed | Early Phase 1 | 5 | NYU Langone HealthOTHER | 1 | May 13, 2020 | clinicaltrials |
| NCT04045847 | CD147-CART Cells in Patients With Recurrent Malignant Glioma. | unknown | Early Phase 1 | 31 | Xijing HospitalOTHER | 1 | May 7, 2020 | clinicaltrials |
| NCT02077543 | Multicenter Safety Trial Assessing an Innovative Tumor Molecular and Cellular Print Medical Device in Glioma(ProTool) | unknown | Early Phase 1 | 150 | University Hospital, GrenobleOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT04315584 | FDG and FDOPA PET Demonstration of Functional Brain Abnormalities | unknown | Early Phase 1 | 5 | University of VirginiaOTHER | 1 | Mar 24, 2020 | clinicaltrials |
| NCT00993057 | Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia | completed | Early Phase 1 | 120 | Northwestern UniversityOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT04051047 | Gemcitabine in Newly-Diagnosed Diffuse Midline Glioma | withdrawn | Early Phase 1 | 0 | University of Michigan Rogel Cancer CenterOTHER | 1 | Nov 27, 2019 | clinicaltrials |
| NCT00795457 | Effects of Vaccinations With HLA-A2-Restricted Glioma Antigen-Peptides in Combination With Poly-ICLC for Adults With High-Risk WHO Grade II Astrocytomas and Oligo-Astrocytomas | completed | Early Phase 1 | 13 | Ian F. Pollack, M.D.OTHER | 1 | Aug 30, 2019 | clinicaltrials |
| NCT03885258 | Melatonin Replacement Therapy in Pinealectomized Patients | completed | Early Phase 1 | 5 | University of Sao PauloOTHER | 1 | Mar 21, 2019 | clinicaltrials |
| NCT02768389 | Feasibility Trial of the Modified Atkins Diet and Bevacizumab for Recurrent Glioblastoma | completed | Early Phase 1 | 18 | Case Comprehensive Cancer CenterOTHER | 1 | Mar 15, 2019 | clinicaltrials |
| NCT02500459 | Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection | terminated | Early Phase 1 | 9 | Michael Vogelbaum, MD, PhDOTHER | 1 | Mar 1, 2019 | clinicaltrials |
| NCT03193463 | Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy | withdrawn | Early Phase 1 | 0 | Michael Vogelbaum, MD, PhDOTHER | 0 | Mar 1, 2019 | clinicaltrials |
| NCT01907165 | Disulfiram in Treating Patients With Glioblastoma Multiforme After Radiation Therapy With Temozolomide | completed | Early Phase 1 | 21 | Washington University School of MedicineOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT01086345 | Radiosurgery Plus Bevacizumab in Glioblastoma | terminated | Early Phase 1 | 9 | Case Comprehensive Cancer CenterOTHER | 1 | Jul 3, 2018 | clinicaltrials |
| NCT01459237 | Effects of Hormone Stimulation on Brain Scans for Cushing s Disease | completed | Early Phase 1 | 30 | National Institute of Neurological Disorders and Stroke (NINDS)NIH | 1 | Jun 14, 2018 | clinicaltrials |
| NCT01091792 | Exploratory Study of the Modulation of the Immune System by VEGF Blockade in Patients With Glioblastoma Multiforme (GBM) | completed | Early Phase 1 | 13 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | May 25, 2018 | clinicaltrials |
| NCT00890786 | A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High-Grade Gliomas and Diffuse Intrinsic Pontine Gliomas | completed | Early Phase 1 | 27 | Children's Hospital Medical Center, CincinnatiOTHER | 1 | May 2, 2018 | clinicaltrials |
| NCT02466828 | qBOLD MRI of Glioblastoma Multiforme for Assessment of Tumor Hypoxia. | completed | Early Phase 1 | 10 | Sunnybrook Health Sciences CentreOTHER | 1 | Apr 18, 2018 | clinicaltrials |
| NCT01737671 | Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study | completed | Early Phase 1 | 7 | M.D. Anderson Cancer CenterOTHER | 1 | Jan 19, 2018 | clinicaltrials |
| NCT02910804 | IRDye800CW-BBN PET-NIRF Imaging Guiding Surgery in Patients With Glioblastoma | unknown | Early Phase 1 | 30 | Beijing Tiantan HospitalOTHER | 1 | Jan 18, 2018 | clinicaltrials |
| NCT01867593 | MET-PET for Newly Diagnosed Glioblastoma | completed | Early Phase 1 | 20 | Massachusetts General HospitalOTHER | 1 | Oct 13, 2017 | clinicaltrials |
| NCT02490930 | A Safety Study of Fingolimod With Radiation and Temozolomide in Newly Diagnosed High Grade Glioma | completed | Early Phase 1 | 5 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Sep 13, 2017 | clinicaltrials |
| NCT02279992 | Pilot Study of Vardenafil and Carboplatin in Patients With Gliomas and Brain Metastases(LevitraCarbo) | terminated | Early Phase 1 | 7 | Cedars-Sinai Medical CenterOTHER | 1 | Sep 11, 2017 | clinicaltrials |
| NCT02452216 | Using Ferumoxytol-Enhanced MRI to Measure Inflammation in Patients With Brain Tumors or Other Conditions of the CNS | completed | Early Phase 1 | 10 | Michael IvOTHER | 1 | Aug 31, 2017 | clinicaltrials |
| NCT02735798 | 64-Cu Labeled Brain PET/MRI for MM-302 in Advanced HER2+ Cancers With Brain Mets | withdrawn | Early Phase 1 | 0 | Pamela MunsterOTHER | 0 | May 4, 2017 | clinicaltrials |
| NCT01996527 | 3T MRI Biomarkers of Glioma Treatment Response | terminated | Early Phase 1 | 7 | Vanderbilt-Ingram Cancer CenterOTHER | 1 | Apr 17, 2017 | clinicaltrials |
| NCT01801371 | 68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma(GRGDG) | unknown | Early Phase 1 | 30 | Peking Union Medical College HospitalOTHER | 1 | Apr 7, 2017 | clinicaltrials |
| NCT02520882 | 68Ga-NOTA-Aca-BBN(7-14) PET/CT in Patients With Primary Gliomas | unknown | Early Phase 1 | 30 | Peking Union Medical College HospitalOTHER | 1 | Apr 7, 2017 | clinicaltrials |
| NCT02278510 | Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma | completed | Early Phase 1 | 3 | Michael Vogelbaum, MD, PhDOTHER | 1 | Mar 31, 2017 | clinicaltrials |
| NCT02976441 | Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas | withdrawn | Early Phase 1 | 0 | Washington University School of MedicineOTHER | 0 | Feb 20, 2017 | clinicaltrials |
| NCT00723463 | Determine if Apparent Diffusion Coefficient (ADC) Values Can Differentiate Tumors From Normal Tissue | completed | Early Phase 1 | 200 | University of MichiganOTHER | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00864864 | Sunitinib Tumor Levels in Patients Not on Enzyme-Inducing Anti-Epileptic Drugs Undergoing Debulking Surgery for Recurrent Glioblastoma | completed | Early Phase 1 | 8 | Massachusetts General HospitalOTHER | 1 | Jul 7, 2016 | clinicaltrials |
| NCT00874861 | HLA-A2-Restricted Glioma Antigen-Peptides Vaccinations With Poly-ICLC for Recurrent WHO Grade II Gliomas | completed | Early Phase 1 | 10 | Ian F. Pollack, M.D.OTHER | 1 | Dec 8, 2015 | clinicaltrials |
| NCT01770626 | A Pilot Study to Determine Nutrition Status in Glioblastoma Multiforme Patients(BEAM) | completed | Early Phase 1 | 40 | University of Alabama at BirminghamOTHER | 1 | Oct 28, 2014 | clinicaltrials |
| NCT01105988 | Evaluating Tumor Pseudoprogression With FLT-PET and MRI | terminated | Early Phase 1 | 2 | Massachusetts General HospitalOTHER | 1 | Jan 6, 2012 | clinicaltrials |
| NCT00440570 | A Study of Therapeutic Amplitude-modulated Electromagnetic Fields in Advanced Tumors(THBC001) | completed | Early Phase 1 | 2 | Pasche, Boris, M.D.INDIV | 1 | Jun 29, 2011 | clinicaltrials |
Data updated 22 days agoSource updated Aug 25, 2021source: clinicaltrials