Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,060 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00314808 | A Pilot Study of Dronabinol for Adult Patients With Primary Gliomas | completed | Phase 1 | 33 | Duke UniversityOTHER | 1 | Jul 16, 2014 | clinicaltrials |
| NCT00609999 | Ph I Dasatinib + Erlotinib in Recurrent MG | completed | Phase 1 | 47 | Duke UniversityOTHER | 1 | Jul 16, 2014 | clinicaltrials |
| NCT00612989 |
| Ph I 5-day Temozolomide + O6-BG in Treatment of Pts w Recurrent / Progressive GBM |
| completed |
| Phase 1 |
| 42 |
| Duke UniversityOTHER |
| 1 |
| Jul 16, 2014 |
| clinicaltrials |
| NCT00946335 | ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors | completed | Phase 1 | 31 | National Cancer Institute (NCI)NIH | 1 | Jul 9, 2014 | clinicaltrials |
| NCT00217412 | Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, Lymphoma, or Leukemia | completed | Phase 1 | 60 | National Cancer Institute (NCI)NIH | 1 | Jun 17, 2014 | clinicaltrials |
| NCT02055196 | Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade Gliomas | withdrawn | Phase 1 | 0 | City of Hope Medical CenterOTHER | 1 | Jun 2, 2014 | clinicaltrials |
| NCT00093613 | Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma | completed | Phase 1 | 47 | National Cancer Institute (NCI)NIH | 1 | May 30, 2014 | clinicaltrials |
| NCT00650923 | Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma | completed | Phase 1 | 61 | National Cancer Institute (NCI)NIH | 1 | May 30, 2014 | clinicaltrials |
| NCT00042991 | Gefitinib and Radiation Therapy in Treating Children With Newly Diagnosed Gliomas | completed | Phase 1 / Phase 2 | 69 | National Cancer Institute (NCI)NIH | 1 | May 28, 2014 | clinicaltrials |
| NCT00095940 | Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors | completed | Phase 1 / Phase 2 | 52 | National Cancer Institute (NCI)NIH | 1 | May 23, 2014 | clinicaltrials |
| NCT01403285 | Peptide-based Glioma Vaccine IMA950 in Patients With Glioblastoma | terminated | Phase 1 | 6 | Immatics Biotechnologies GmbHINDUSTRY | 1 | May 19, 2014 | clinicaltrials |
| NCT00079339 | Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma | completed | Phase 1 / Phase 2 | 51 | National Cancer Institute (NCI)NIH | 1 | May 15, 2014 | clinicaltrials |
| NCT00575146 | Ketogenic Diet for Recurrent Glioblastoma(ERGO) | completed | Phase 1 | 20 | University Hospital TuebingenOTHER | 1 | May 2, 2014 | clinicaltrials |
| NCT01231919 | MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia | completed | Phase 1 | 45 | National Cancer Institute (NCI)NIH | 2 | Apr 29, 2014 | clinicaltrials |
| NCT00822458 | GDC-0449 in Treating Young Patients With Medulloblastoma That is Recurrent or Did Not Respond to Previous Treatment | completed | Phase 1 | 34 | National Cancer Institute (NCI)NIH | 1 | Apr 2, 2014 | clinicaltrials |
| NCT00003141 | Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Infants With Malignant Brain or Spinal Cord Tumors | completed | Phase 1 | 94 | Children's Oncology GroupNETWORK | 3 | Mar 28, 2014 | clinicaltrials |
| NCT02084927 | Hyperbaric Oxygen Therapy Can Improve Neurological State Post Meningioma Removal Surgery | unknown | Phase 1 | 62 | Assaf-Harofeh Medical CenterOTHER_GOV | 1 | Mar 12, 2014 | clinicaltrials |
| NCT02080949 | Phase I Dose Escalation in Patients With 1-3 Unresectable Brain Metastases | withdrawn | Phase 1 | 0 | Barretos Cancer HospitalOTHER | 1 | Mar 7, 2014 | clinicaltrials |
| NCT00499811 | Vorinostat in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphoma and Liver Dysfunction | completed | Phase 1 | 15 | National Cancer Institute (NCI)NIH | 1 | Feb 24, 2014 | clinicaltrials |
| NCT00005602 | Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas | completed | Phase 1 | 13 | Children's Oncology GroupNETWORK | 1 | Feb 21, 2014 | clinicaltrials |
| NCT01516983 | Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation | completed | Phase 1 / Phase 2 | 15 | Betta Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Feb 17, 2014 | clinicaltrials |
| NCT00006024 | Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma | completed | Phase 1 | 32 | Children's Oncology GroupNETWORK | 7 | Feb 13, 2014 | clinicaltrials |
| NCT01407341 | Beta-Tricalcium Phosphate Bone Graft in Treating Patients Undergoing Surgery For Metastatic Spine Cancer | terminated | Phase 1 | 1 | University of Southern CaliforniaOTHER | 1 | Feb 6, 2014 | clinicaltrials |
| NCT01048892 | Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features | completed | Phase 1 | 22 | Children's Oncology GroupNETWORK | 1 | Jan 30, 2014 | clinicaltrials |
| NCT02050243 | The Use of 5-aminolevulinic Acid (ALA) as an Intraoperative Tumor Marker for Resection of Pediatric Central Nervous System (CNS) Tumors(5-ALA) | unknown | Phase 1 / Phase 2 | 100 | Tel-Aviv Sourasky Medical CenterOTHER_GOV | 1 | Jan 30, 2014 | clinicaltrials |
| NCT00979173 | Pharmacokinetics (PK) Study of AC480 for Recurrent Glioma | completed | Phase 1 | 5 | Annick DesjardinsOTHER | 1 | Jan 29, 2014 | clinicaltrials |
| NCT00387920 | Sunitinib in Treating Young Patients With Refractory Solid Tumors | completed | Phase 1 | 35 | National Cancer Institute (NCI)NIH | 2 | Jan 28, 2014 | clinicaltrials |
| NCT01854099 | Peptide Vaccine for Glioblastoma Against Cytomegalovirus Antigens(PERFORMANCE) | withdrawn | Phase 1 | 0 | University of FloridaOTHER | 0 | Jan 14, 2014 | clinicaltrials |
| NCT00107471 | Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma | terminated | Phase 1 / Phase 2 | 7 | Children's Oncology GroupNETWORK | 4 | Dec 10, 2013 | clinicaltrials |
| NCT00949026 | Assessment of Systemically Administered Torisel Delivery to Brain Tumors by Intratumoral Microdialysis | withdrawn | Phase 1 | 0 | Emory UniversityOTHER | 1 | Nov 21, 2013 | clinicaltrials |
| NCT01640509 | Synchrotron Radiation to the Treatment of Intracranial Tumors(ESRF) | unknown | Phase 1 / Phase 2 | 50 | University Hospital, GrenobleOTHER | 1 | Nov 11, 2013 | clinicaltrials |
| NCT00919737 | Study of NPC-08 is to Treat for Newly-Diagnosed Malignant Glioma and Recurrent Glioblastoma Multiforme | completed | Phase 1 / Phase 2 | 24 | NobelpharmaINDUSTRY | 1 | Oct 30, 2013 | clinicaltrials |
| NCT00610571 | Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas | completed | Phase 1 | 62 | Katy PetersOTHER | 1 | Oct 25, 2013 | clinicaltrials |
| NCT00385853 | PTK787/ZK 222584 in Combination With Temozolomide and Radiation in Patients With Glioblastoma Taking Enzyme-Inducing Anti-Epileptic Drugs | completed | Phase 1 | 19 | Massachusetts General HospitalOTHER | 1 | Oct 21, 2013 | clinicaltrials |
| NCT00052780 | Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors | completed | Phase 1 | 72 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00063973 | Cilengitide in Treating Children With Refractory Primary Brain Tumors | completed | Phase 1 | 24 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00100880 | Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors | completed | Phase 1 | 45 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00293345 | 3-AP and Gemcitabine in Treating Patients With Advanced Solid Tumors or Lymphoma | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT00929903 | Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment | completed | Phase 1 | 55 | National Cancer Institute (NCI)NIH | 1 | Sep 30, 2013 | clinicaltrials |
| NCT01332929 | Safety Evaluation of a Combination of Brain Radiation Therapy and Bevacizumab (Avastin®) for Treatment of Brain Metastasis | completed | Phase 1 | 21 | Centre Francois BaclesseOTHER | 1 | Sep 12, 2013 | clinicaltrials |
| NCT01445119 | A Phase I Trial of Enzastaurin (LY317615) in Combination With Carboplatin in Adults With Recurrent Gliomas | completed | Phase 1 | 58 | Eli Lilly and CompanyINDUSTRY | 1 | Aug 28, 2013 | clinicaltrials |
| NCT01697514 | A Study of LY2940680 in Pediatric Medulloblastoma or Rhabdomyosarcoma | withdrawn | Phase 1 | 0 | Eli Lilly and CompanyINDUSTRY | 1 | Aug 27, 2013 | clinicaltrials |
| NCT01205334 | Administration of CMV-Specific Cytotoxic T Cells in Patients With Glioblastoma Multiforme(COGLI) | terminated | Phase 1 / Phase 2 | 2 | Baylor College of MedicineOTHER | 1 | Aug 26, 2013 | clinicaltrials |
| NCT00001251 | Phase I Study of Intrathecal Mafosfamide | completed | Phase 1 | 65 | National Cancer Institute (NCI)NIH | 1 | Aug 19, 2013 | clinicaltrials |
| NCT01369121 | Tolerability Study of Xerecept® in Pediatric Patients | terminated | Phase 1 / Phase 2 | 15 | Celtic Pharma Development ServicesINDUSTRY | 1 | Jul 30, 2013 | clinicaltrials |
| NCT00762255 | A Phase I Trial of Vorinostat in Combination With Bevacizumab & Irinotecan in Recurrent Glioblastoma | completed | Phase 1 | 19 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Jul 25, 2013 | clinicaltrials |
| NCT00003022 | Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer | completed | Phase 1 | — | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 3, 2013 | clinicaltrials |
| NCT00012181 | Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | Jul 2, 2013 | clinicaltrials |
| NCT00994500 | Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma | completed | Phase 1 | 20 | National Cancer Institute (NCI)NIH | 1 | Jul 2, 2013 | clinicaltrials |
| NCT00822887 | Dose Escalation Study of Vandetanib With Hypofractionated Stereotactic Radiotherapy in Recurrent Malignant Gliomas(IRUSZACT0073) | completed | Phase 1 | 13 | University of Colorado, DenverOTHER | 1 | Jun 26, 2013 | clinicaltrials |
Data updated 23 days agoSource updated Jul 16, 2014source: clinicaltrials