Cancer Family
Central Nervous System Neoplasm
CI-CAN-00000118Explore in graph →
Non-malignant1,345 active trials7 approved drugs177 evidence items
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Cancer Family
CI-CAN-00000118Explore in graph →
Clinical trials
5,058 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00295815 | Enzastaurin Versus Lomustine in Glioblastoma | completed | Phase 3 | 397 | Eli Lilly and CompanyINDUSTRY | 14 | Sep 12, 2019 | clinicaltrials |
| NCT00884741 | Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma | completed | Phase 3 | 637 | National Cancer Institute (NCI)NIH | 3 | Jul 24, 2019 | clinicaltrials |
| NCT02511405 |
| A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE)(GLOBE) |
| completed |
| Phase 3 |
| 252 |
| Vascular Biogenics Ltd. operating as VBL TherapeuticsINDUSTRY |
| 3 |
| Oct 23, 2018 |
| clinicaltrials |
| NCT00085098 | Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor | completed | Phase 3 | 24 | Children's Oncology GroupNETWORK | 4 | Sep 7, 2018 | clinicaltrials |
| NCT00749723 | Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children(HIT-REZ-2005) | completed | Phase 2 / Phase 3 | 174 | University Hospital, BonnOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT01601314 | Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients(MAGNA) | completed | Phase 3 | 55 | Sara VareaOTHER | 1 | Jan 17, 2018 | clinicaltrials |
| NCT01480479 | Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma(ACT IV) | completed | Phase 3 | 745 | Celldex TherapeuticsINDUSTRY | 24 | Jan 16, 2018 | clinicaltrials |
| NCT00943826 | A Study of Bevacizumab (Avastin®) in Combination With Temozolomide and Radiotherapy in Participants With Newly Diagnosed Glioblastoma | completed | Phase 3 | 921 | Hoffmann-La RocheINDUSTRY | 24 | Sep 25, 2017 | clinicaltrials |
| NCT03271918 | Cabergoline in Nonfunctioning Pituitary Adenomas | completed | Phase 3 | 140 | University of Sao Paulo General HospitalOTHER | 1 | Sep 7, 2017 | clinicaltrials |
| NCT00522951 | SH L 562BB Phase II/III Dose Justification and Gadoteridol-controlled Comparative Study | completed | Phase 3 | 165 | BayerINDUSTRY | 1 | Aug 28, 2017 | clinicaltrials |
| NCT01149109 | Efficacy and Safety Study of Lomustine/Temozolomide Combination Therapy vs. Standard Therapy for Glioblastoma Patients(CeTeG) | completed | Phase 3 | 141 | University Hospital, BonnOTHER | 1 | Jun 14, 2017 | clinicaltrials |
| NCT00335075 | Efficacy and Safety of Temodal vs Semustine in Subjects With Recurrent Glioblastoma or Anaplastic Astrocytoma (Study P03644) | completed | Phase 3 | 151 | Merck Sharp & Dohme LLCINDUSTRY | 0 | May 15, 2017 | clinicaltrials |
| NCT00916409 | Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM) | completed | Phase 3 | 700 | NovoCure Ltd.INDUSTRY | 12 | Apr 10, 2017 | clinicaltrials |
| NCT01724801 | Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer(BRAIN) | completed | Phase 3 | 176 | Guangdong Association of Clinical TrialsOTHER | 1 | Mar 1, 2017 | clinicaltrials |
| NCT00777153 | Cediranib in Combination With Lomustine Chemotherapy in Recurrent Glioblastoma(REGAL) | completed | Phase 3 | 423 | AstraZenecaINDUSTRY | 10 | Dec 28, 2016 | clinicaltrials |
| NCT00088400 | Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors | completed | Phase 3 | 30 | National Institute of Neurological Disorders and Stroke (NINDS)NIH | 1 | Sep 22, 2016 | clinicaltrials |
| NCT00280475 | A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis | completed | Phase 3 | 270 | Haruhiko FukudaOTHER | 1 | Sep 22, 2016 | clinicaltrials |
| NCT01620138 | Response to Cabergoline and Pasireotide in Non-functioning Pituitary Adenomas and Resistant Prolactinomas | completed | Phase 2 / Phase 3 | 21 | Universidade Federal do Rio de JaneiroOTHER | 1 | Aug 22, 2016 | clinicaltrials |
| NCT02636634 | Non Invasive Methods for Differential Diagnosis Radionecrosis/Recurrence After Radiosurgery of Brain Metastases(CV-METANEC) | completed | Phase 3 | 90 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Apr 11, 2016 | clinicaltrials |
| NCT00123760 | Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Cancer or Suspected Cancer | completed | Phase 2 / Phase 3 | 10,838 | AHS Cancer Control AlbertaOTHER | 1 | Feb 25, 2016 | clinicaltrials |
| NCT01364064 | Conventional Adjuvant Temozolomide With Dose Intensive Temozolomide in Patients With Newly Diagnosed Glioblastoma | completed | Phase 3 | 1,153 | King Faisal Specialist Hospital & Research CenterOTHER | 0 | Feb 25, 2016 | clinicaltrials |
| NCT00789828 | Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)(EXIST-1) | completed | Phase 3 | 117 | Novartis PharmaceuticalsINDUSTRY | 10 | Feb 3, 2016 | clinicaltrials |
| NCT01450449 | Short Course vs. Standard Course Radiotherapy in Elderly and/or Frail Patients With Glioblastoma Multiforme | completed | Phase 3 | 115 | International Atomic Energy AgencyOTHER_GOV | 14 | Mar 24, 2015 | clinicaltrials |
| NCT00681551 | Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis | completed | Phase 3 | 45 | BayerINDUSTRY | 1 | Dec 15, 2014 | clinicaltrials |
| NCT00689221 | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Methylated Gene Promoter Status(CENTRIC) | completed | Phase 3 | 545 | EMD SeronoINDUSTRY | 2 | Nov 4, 2014 | clinicaltrials |
| NCT00088166 | XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors | completed | Phase 3 | 200 | Celtic Pharma Development ServicesINDUSTRY | 2 | Aug 13, 2014 | clinicaltrials |
| NCT00002875 | Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma | completed | Phase 3 | 421 | Children's Oncology GroupNETWORK | 5 | Aug 1, 2014 | clinicaltrials |
| NCT01460706 | Imaging Malignant Glioma With 68Ga-DOTATOC PET/CT(DOTAGLI) | completed | Phase 2 / Phase 3 | 30 | Turku University HospitalOTHER_GOV | 1 | Dec 12, 2013 | clinicaltrials |
| NCT00003859 | Surgery Plus Radiation Therapy With or Without Chemotherapy in Treating Children With Primitive Neuroectodermal Tumors of the CNS | completed | Phase 3 | 230 | Societe Internationale d'Oncologie PediatriqueOTHER | 1 | Dec 4, 2013 | clinicaltrials |
| NCT00293358 | Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain | completed | Phase 3 | 500 | Children's Cancer and Leukaemia GroupOTHER | 2 | Sep 17, 2013 | clinicaltrials |
| NCT00002944 | Combination Chemotherapy in Treating Children With Progressive Brain Tumors | completed | Phase 3 | 428 | Children's Oncology GroupNETWORK | 6 | Sep 9, 2013 | clinicaltrials |
| NCT00006461 | Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor | completed | Phase 3 | 82 | Children's Oncology GroupNETWORK | 1 | Aug 9, 2013 | clinicaltrials |
| NCT00226655 | An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies | completed | Phase 3 | 112 | Celtic Pharma Development ServicesINDUSTRY | 2 | Aug 31, 2012 | clinicaltrials |
| NCT00389883 | Anaesthesia for Supratentorial Tumor Resection | completed | Phase 3 | 69 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jul 10, 2012 | clinicaltrials |
| NCT01635140 | Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children | completed | Phase 3 | 64 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Jul 9, 2012 | clinicaltrials |
| NCT00379470 | Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM) | completed | Phase 3 | 236 | NovoCure Ltd.INDUSTRY | 7 | May 1, 2012 | clinicaltrials |
| NCT01167322 | Study of NPC-07 for Fluorescence-guided Resection of Malignant Gliomas | completed | Phase 3 | 45 | NobelpharmaINDUSTRY | 1 | Apr 27, 2012 | clinicaltrials |
| NCT00241670 | Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid | completed | Phase 3 | 415 | medac GmbHINDUSTRY | 0 | Apr 26, 2012 | clinicaltrials |
| NCT00460395 | Surgery Versus Stereotactic Radiosurgery in the Treatment of Single Brain Metastasis: A Randomized Trial | completed | Phase 3 | 64 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 24, 2012 | clinicaltrials |
| NCT01502241 | Phase III Trial of Primary Radio- or Chemotherapy in Malignant Astrocytoma of the Elderly(Methusalem) | completed | Phase 3 | 412 | Heidelberg UniversityOTHER | 2 | Dec 30, 2011 | clinicaltrials |
| NCT00076986 | The PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma Multiforme | completed | Phase 3 | 300 | INSYS Therapeutics IncINDUSTRY | 6 | Jun 6, 2011 | clinicaltrials |
| NCT00154375 | Study of Imatinib Mesylate in Combination With Hydroxyurea Versus Hydroxyurea Alone as an Oral Therapy in Patients With Temozolomide Resistant Progressive Glioblastoma | completed | Phase 3 | 240 | Novartis PharmaceuticalsINDUSTRY | 1 | Apr 26, 2011 | clinicaltrials |
| NCT00306683 | Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions | completed | Phase 3 | 40 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Feb 18, 2011 | clinicaltrials |
| NCT00124761 | A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases | completed | Phase 3 | 22 | Royal Adelaide HospitalOTHER | 1 | Sep 6, 2010 | clinicaltrials |
| NCT00224978 | Chloroquine for Treatment of Glioblastoma Multiforme | completed | Phase 3 | — | National Institute of Neurology and Neurosurgery, MexicoOTHER | 1 | Nov 18, 2009 | clinicaltrials |
| NCT00181350 | Serial CT Scans in Fractionated Stereotactic Radiotherapy | completed | Phase 3 | 20 | Maastricht Radiation OncologyOTHER | 1 | Jun 30, 2009 | clinicaltrials |
| NCT00138788 | Brain Metastases Study: Radiotherapy Fractionation Schemes in the Treatment of Brain Metastases | completed | Phase 3 | 112 | St George Hospital, AustraliaOTHER | 1 | Nov 20, 2008 | clinicaltrials |
| NCT00717210 | Randomized Phase III Study of Sequential Radiochemotherapy of Anaplastic Glioma With PCV or Temozolomide(NOA-04) | completed | Phase 3 | 318 | Neuro-Oncology Working Group of the German Cancer SocietyNETWORK | 1 | Jul 17, 2008 | clinicaltrials |
| NCT00068952 | Study of IV Edotecarin Vs Temozolomide or Carmustine (BCNU) or Lomustine (CCNU) in Patients With Glioblastoma Multiforme | completed | Phase 3 | 118 | PfizerINDUSTRY | 13 | Apr 1, 2008 | clinicaltrials |
Data updated 23 days agoSource updated Sep 12, 2019source: clinicaltrials