Cancer Family
Breast Neoplasm
CI-CAN-00000007Explore in graph →
Non-malignant2,894 active trials43 approved drugs310 evidence items
- NCIt
- C2910
- OncoTree
- BNNOS
- MeSH
- D000069584
- MeSH
- D001943
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Cancer Family
CI-CAN-00000007Explore in graph →
Clinical trials
13,871 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02162719 | A Study Assessing the Safety and Efficacy of Adding Ipatasertib to Paclitaxel Treatment in Participants With Breast Cancer That Has Spread Beyond the Initial Site, and the Cancer Does Not Have Certain Hormonal Receptors(LOTUS) | completed | Phase 2 | 124 | Genentech, Inc.INDUSTRY | 8 | Mar 10, 2021 | clinicaltrials |
| NCT03577743 | Effect of Bevacizumab in Metastatic Triple Negative Breast Cancer | completed | Phase 2 | 54 | Assiut UniversityOTHER | 1 | Mar 9, 2021 |
| clinicaltrials |
| NCT02687490 | Abraxane in Patients With Visceral Metastases Dominant Metastatic Breast Cancer | completed | Phase 2 | 81 | Fudan UniversityOTHER | 1 | Mar 1, 2021 | clinicaltrials |
| NCT01783444 | A Phase II Study of Everolimus in Combination With Exemestane Versus Everolimus Alone Versus Capecitabine in Advance Breast Cancer.(BOLERO-6) | completed | Phase 2 | 309 | Novartis PharmaceuticalsINDUSTRY | 18 | Feb 26, 2021 | clinicaltrials |
| NCT00871858 | Anastrozole or Fulvestrant in Treating Postmenopausal Patients With Breast Cancer(HORGEN) | completed | Phase 2 | 120 | Institut BergoniéOTHER | 1 | Feb 24, 2021 | clinicaltrials |
| NCT01842321 | Abiraterone Acetate in Molecular Apocrine Breast Cancer(AMA) | completed | Phase 2 | 34 | UNICANCEROTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT01989546 | Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations | completed | Phase 1 / Phase 2 | 9 | National Cancer Institute (NCI)NIH | 1 | Feb 23, 2021 | clinicaltrials |
| NCT00470301 | Tipifarnib and Combination Chemotherapy in Treating Patients With Stage II or Stage III Breast Cancer | completed | Phase 1 / Phase 2 | 60 | National Cancer Institute (NCI)NIH | 1 | Feb 16, 2021 | clinicaltrials |
| NCT02685059 | Addition of PD-L1 Antibody MEDI4736 to a Taxane-anthracycline Chemotherapy in Triple Negative Breast Cancer(GeparNuevo) | completed | Phase 2 | 174 | GBG Forschungs GmbHOTHER | 1 | Feb 15, 2021 | clinicaltrials |
| NCT01015131 | 18F-FLT-PET in Breast Cancer (MK-0000-139) | completed | Phase 2 | 46 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Feb 11, 2021 | clinicaltrials |
| NCT01150513 | Docetaxel+Carboplatin vs Epirubicin+Cyclophosphamide Followed by Docetaxel as Adjuvant Treatment in Triple-negative Breast Cancer | completed | Phase 2 / Phase 3 | 320 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT02139358 | Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer | completed | Phase 1 / Phase 2 | 15 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT01554371 | Eribulin in Combination With Cyclophosphamide in Patients With Solid Tumor Malignancies | completed | Phase 1 / Phase 2 | 44 | University of California, San FranciscoOTHER | 1 | Feb 3, 2021 | clinicaltrials |
| NCT04166253 | Protective Role of Vitamin D in Breast Cancer Patients Treated With Doxorubicin(VDDOXO) | completed | Phase 2 | 100 | Damanhour UniversityOTHER | 1 | Feb 3, 2021 | clinicaltrials |
| NCT02682693 | Denosumab as an add-on Neoadjuvant Treatment (GeparX)(GeparX) | completed | Phase 2 | 780 | GBG Forschungs GmbHOTHER | 1 | Feb 2, 2021 | clinicaltrials |
| NCT03066947 | SV-BR-1-GM in Metastatic or Locally Recurrent Breast Cancer | completed | Phase 1 / Phase 2 | 24 | BriaCell Therapeutics CorporationINDUSTRY | 1 | Jan 29, 2021 | clinicaltrials |
| NCT02725489 | Pilot Study of Durvalumab and Vigil in Advanced Women's Cancers | completed | Phase 2 | 13 | Mary Crowley Medical Research CenterOTHER | 1 | Jan 27, 2021 | clinicaltrials |
| NCT02878057 | Multicenter Phase II Study of Apatinib in Patients With Advanced Breast Cancer(CABC006) | completed | Phase 2 | 30 | Peking University Cancer Hospital & InstituteOTHER | 0 | Jan 27, 2021 | clinicaltrials |
| NCT00442260 | Doxorubicin HCL Liposome Injection (DOXIL) in Combination With Abraxane in Patients With Metastatic Breast Cancer | completed | Phase 1 / Phase 2 | 2 | West Virginia UniversityOTHER | 1 | Jan 22, 2021 | clinicaltrials |
| NCT01289353 | Concurrent Adjuvant Carboplatin and Accelerated Radiotherapy for Triple Negative Breast Cancer | completed | Phase 1 / Phase 2 | 92 | NYU Langone HealthOTHER | 1 | Jan 12, 2021 | clinicaltrials |
| NCT01323530 | A Confirmation Study of Eribulin in Combination With Capecitabine | completed | Phase 1 / Phase 2 | 76 | Eisai LimitedINDUSTRY | 3 | Jan 11, 2021 | clinicaltrials |
| NCT02517593 | Genetic Risk Estimation of Breast Cancer Prior to Preventive Medication Uptake(GENRE) | completed | Phase 1 / Phase 2 | 151 | Mayo ClinicOTHER | 2 | Dec 30, 2020 | clinicaltrials |
| NCT00958971 | Safety and Efficacy of TKI258 in FGFR1 Amplified and Non-amplified Metastatic HER2 Negative Breast Cancer | completed | Phase 2 | 43 | Novartis PharmaceuticalsINDUSTRY | 8 | Dec 19, 2020 | clinicaltrials |
| NCT02308020 | A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain | completed | Phase 2 | 162 | Eli Lilly and CompanyINDUSTRY | 9 | Dec 19, 2020 | clinicaltrials |
| NCT00526045 | Phase I-II Study to Determine the Maximum Tolerated Dose (MTD) of AUY922 in Advanced Solid Malignancies, and Efficacy in HER2+ or ER+ Locally Advanced or Metastatic Breast Cancer Patients | completed | Phase 1 / Phase 2 | 117 | Novartis PharmaceuticalsINDUSTRY | 4 | Dec 17, 2020 | clinicaltrials |
| NCT00600275 | A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer | completed | Phase 1 / Phase 2 | 57 | Novartis PharmaceuticalsINDUSTRY | 3 | Dec 17, 2020 | clinicaltrials |
| NCT02447003 | Study of Pembrolizumab (MK-3475) Monotherapy for Metastatic Triple-Negative Breast Cancer (MK-3475-086/KEYNOTE-086) | completed | Phase 2 | 254 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Dec 16, 2020 | clinicaltrials |
| NCT04659551 | Neoadjuvant Chemo-endocrine Therapy and Immunotherapy for Pre-menopausal Luminal B Breast Cancer Patients(GIADA) | completed | Phase 2 | 43 | Istituto Oncologico Veneto IRCCSOTHER | 1 | Dec 9, 2020 | clinicaltrials |
| NCT01271920 | Combination of AUY922 With Trastuzumab in HER2+ Advanced Breast Cancer Patients Previously Treated With Trastuzumab | completed | Phase 1 / Phase 2 | 45 | Novartis PharmaceuticalsINDUSTRY | 8 | Dec 8, 2020 | clinicaltrials |
| NCT00290745 | Tamoxifen or Letrozole in Treating Women With Ductal Carcinoma in Situ | completed | Phase 1 / Phase 2 | 79 | University of California, San FranciscoOTHER | 1 | Dec 4, 2020 | clinicaltrials |
| NCT01570036 | Combination Immunotherapy With Herceptin and the HER2 Vaccine NeuVax | completed | Phase 2 | 275 | George E. PeoplesINDUSTRY | 1 | Dec 2, 2020 | clinicaltrials |
| NCT03106077 | Mirvetuximab Soravtansine as First Line in Treating Patients With Triple Negative Breast Cancer | completed | Phase 2 | 96 | M.D. Anderson Cancer CenterOTHER | 1 | Dec 2, 2020 | clinicaltrials |
| NCT03535961 | Apatinib Combined With Oral Etoposide in Metastatic HER2 Negative Breast Cancer | completed | Phase 2 | 32 | Chinese Academy of Medical SciencesOTHER | 1 | Dec 2, 2020 | clinicaltrials |
| NCT02757651 | KORTUC: Intra-tumoural Hydrogen Peroxide as a Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer in Terms of Toxicity and Tumour Response | completed | Phase 1 / Phase 2 | 12 | Institute of Cancer Research, United KingdomOTHER | 1 | Nov 27, 2020 | clinicaltrials |
| NCT03819010 | Neoadjuvant Letrozole and Palbociclib in Patients With Stage II-IIIB Breast Cancer, HR+, HER2 -(DxCARTES) | completed | Phase 2 | 66 | MedSIROTHER | 2 | Nov 27, 2020 | clinicaltrials |
| NCT02280252 | Study of Concurrent Paclitaxel and Radiation: Correlation of Tumor Profiles With Pathologic Response | completed | Phase 2 | 69 | NYU Langone HealthOTHER | 1 | Nov 23, 2020 | clinicaltrials |
| NCT03165149 | Effect of a Topical Ketamine on Acute and Chronic Pain, Dose Finding | completed | Phase 2 / Phase 3 | 90 | Assiut UniversityOTHER | 1 | Nov 3, 2020 | clinicaltrials |
| NCT01491737 | A Study of Pertuzumab in Combination With Trastuzumab Plus an Aromatase Inhibitor in Participants With Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive and Hormone Receptor-Positive Advanced Breast Cancer(PERTAIN) | completed | Phase 2 | 258 | Hoffmann-La RocheINDUSTRY | 8 | Oct 28, 2020 | clinicaltrials |
| NCT01629615 | A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer | completed | Phase 2 | 50 | SOLTI Breast Cancer Research GroupOTHER | 2 | Oct 28, 2020 | clinicaltrials |
| NCT03394287 | A Trial of SHR-1210 (an Anti-PD-1 Antibody) in Combination With Apatinib in Patients With Advanced TNBC | completed | Phase 2 | 40 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 1 | Oct 23, 2020 | clinicaltrials |
| NCT00810797 | Exemestane in Treating Postmenopausal Women With Stage IV Breast Cancer | completed | Phase 2 | 36 | City of Hope Medical CenterOTHER | 1 | Oct 19, 2020 | clinicaltrials |
| NCT00574587 | Trial for Locally Advanced Breast Cancer Using Vorinostat Plus Chemotherapy | completed | Phase 1 / Phase 2 | 55 | Albert Einstein College of MedicineOTHER | 1 | Oct 14, 2020 | clinicaltrials |
| NCT00033514 | Trastuzumab and Erlotinib as First-Line Therapy in Treating Women With Metastatic Breast Cancer Associated With HER2/Neu Overexpression | completed | Phase 1 / Phase 2 | 27 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Oct 8, 2020 | clinicaltrials |
| NCT04426435 | Effects a Honey Based Syrup on Blood Parameters in Patients With Breast Cancer | completed | Phase 2 | 60 | Shiraz University of Medical SciencesOTHER | 1 | Oct 8, 2020 | clinicaltrials |
| NCT01387373 | Intra-hepatic Chemotherapy in Patient With Non-resectable Liver Metastases From Breast Cancer | completed | Phase 2 | 14 | Dorte NielsenOTHER | 1 | Oct 5, 2020 | clinicaltrials |
| NCT02997995 | Durvalumab and Endocrine Therapy in ER+/Her2- Breast Cancer After CD8+ Infiltration Effective Immune-Attractant Exposure(ULTIMATE) | completed | Phase 2 | 61 | UNICANCEROTHER | 3 | Sep 30, 2020 | clinicaltrials |
| NCT01525589 | A Phase II Clinical Trial of PM01183 in BRCA 1/2-Associated or Unselected Metastatic Breast Cancer | completed | Phase 2 | 111 | PharmaMarINDUSTRY | 2 | Sep 25, 2020 | clinicaltrials |
| NCT02015559 | Mucoadhesive Oral Wound Rinse in Preventing and Treating Stomatitis in Patients With ER- or PR-Positive Metastatic or Locally Recurrent Breast Cancer That Cannot be Removed by Surgery Receiving Everolimus | completed | Phase 2 | 61 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Sep 21, 2020 | clinicaltrials |
Data updated 24 days agoSource updated Mar 10, 2021source: clinicaltrials