Subtype
Brain Neoplasm
CI-CAN-00002030Explore in graph →
Non-malignant511 active trials34 evidence items
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00002030Explore in graph →
Clinical trials
2,117 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02040376 | Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma | completed | Phase 3 | 24 | The Hospital for Sick ChildrenOTHER | 1 | Sep 24, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 |
| clinicaltrials |
| NCT00085735 | Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma | completed | Phase 3 | 549 | Children's Oncology GroupNETWORK | 7 | Jun 9, 2026 | clinicaltrials |
| NCT00392327 | Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET | completed | Phase 3 | 379 | Children's Oncology GroupNETWORK | 5 | Jun 8, 2026 | clinicaltrials |
| NCT02860923 | Efficacy and Safety of Exenatide in the Treatment of Hypothalamic Obesity After Craniopharyngioma Therapy(CRANIOEXE) | completed | Phase 3 | 42 | University Hospital, BordeauxOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT01096368 | Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma | completed | Phase 3 | 479 | Children's Oncology GroupNETWORK | 4 | Apr 30, 2026 | clinicaltrials |
| NCT06057168 | Performance of Elucirem in DSC-MRI Perfusion of Brain Gliomas(GDX-44-016) | completed | Phase 3 | 138 | GuerbetINDUSTRY | 3 | Jan 29, 2026 | clinicaltrials |
| NCT00336024 | Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma | completed | Phase 3 | 91 | Children's Oncology GroupNETWORK | 4 | Jan 23, 2026 | clinicaltrials |
| NCT01351870 | Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma (PNET4)(SIOP-PNET-4) | completed | Phase 3 | 52 | Institut CurieOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT04410133 | Study to Establish the Diagnostic Performance of 18F Fluciclovine PET in Detecting Recurrent Brain Metastases(REVELATE) | completed | Phase 3 | 151 | Blue Earth DiagnosticsINDUSTRY | 1 | Aug 28, 2025 | clinicaltrials |
| NCT01951482 | Pemetrexed/Platinum With or Without Bevacizumab in Brain Metastases From Patients With EGFR/ALK Negative Non-Squamous Non-small Cell Lung Cancer | completed | Phase 3 | 160 | Sun Yat-sen UniversityOTHER | 1 | Aug 17, 2025 | clinicaltrials |
| NCT02667587 | An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)(CheckMate548) | completed | Phase 3 | 716 | Bristol-Myers SquibbINDUSTRY | 19 | Jun 18, 2025 | clinicaltrials |
| NCT05807893 | Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases(SUPER BRAIN) | completed | Phase 2 / Phase 3 | 40 | Sun Yat-sen UniversityOTHER | 1 | Nov 13, 2024 | clinicaltrials |
| NCT01236560 | Vorinostat, Temozolomide, or Bevacizumab in Combination With Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients With Newly Diagnosed High-Grade Glioma | completed | Phase 2 / Phase 3 | 101 | National Cancer Institute (NCI)NIH | 2 | Feb 20, 2024 | clinicaltrials |
| NCT00716976 | Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy | completed | Phase 3 | 131 | Children's Oncology GroupNETWORK | 3 | Nov 9, 2023 | clinicaltrials |
| NCT00548756 | Randomized Trial Comparing Radiosurgery With vs Without Whole Brain Radiotherapy | completed | Phase 3 | 152 | M.D. Anderson Cancer CenterOTHER | 1 | Jun 7, 2023 | clinicaltrials |
| NCT02879682 | nTMS for Motor Mapping of Rolandic Lesions(Motorstim) | completed | Phase 2 / Phase 3 | 330 | Technical University of MunichOTHER | 3 | Jun 1, 2023 | clinicaltrials |
| NCT02617589 | An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer)(CheckMate 498) | completed | Phase 3 | 560 | Bristol-Myers SquibbINDUSTRY | 19 | Mar 28, 2023 | clinicaltrials |
| NCT02881957 | Hypovitaminosis D in Neurocritical Patients | completed | Phase 2 / Phase 3 | 274 | University of UtahOTHER | 1 | Jun 15, 2022 | clinicaltrials |
| NCT00369785 | Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors | completed | Phase 3 | 198 | Wake Forest University Health SciencesOTHER | 1 | Oct 20, 2021 | clinicaltrials |
| NCT00033254 | Radiation Therapy With or Without Thalidomide in Treating Patients With Brain Metastases | completed | Phase 3 | 332 | National Cancer Institute (NCI)NIH | 1 | Oct 30, 2020 | clinicaltrials |
| NCT00884741 | Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma | completed | Phase 3 | 637 | National Cancer Institute (NCI)NIH | 3 | Jul 24, 2019 | clinicaltrials |
| NCT00085098 | Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor | completed | Phase 3 | 24 | Children's Oncology GroupNETWORK | 4 | Sep 7, 2018 | clinicaltrials |
| NCT00749723 | Therapy Optimization Trial for the Treatment of Relapsed or Refractory Brain Tumors in Children(HIT-REZ-2005) | completed | Phase 2 / Phase 3 | 174 | University Hospital, BonnOTHER | 1 | Jul 20, 2018 | clinicaltrials |
| NCT01601314 | Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients(MAGNA) | completed | Phase 3 | 55 | Sara VareaOTHER | 1 | Jan 17, 2018 | clinicaltrials |
| NCT01480479 | Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma(ACT IV) | completed | Phase 3 | 745 | Celldex TherapeuticsINDUSTRY | 24 | Jan 16, 2018 | clinicaltrials |
| NCT03271918 | Cabergoline in Nonfunctioning Pituitary Adenomas | completed | Phase 3 | 140 | University of Sao Paulo General HospitalOTHER | 1 | Sep 7, 2017 | clinicaltrials |
| NCT00522951 | SH L 562BB Phase II/III Dose Justification and Gadoteridol-controlled Comparative Study | completed | Phase 3 | 165 | BayerINDUSTRY | 1 | Aug 28, 2017 | clinicaltrials |
| NCT01724801 | Icotinib or Whole Brain Irradiation in EGFR-mutant Lung Cancer(BRAIN) | completed | Phase 3 | 176 | Guangdong Association of Clinical TrialsOTHER | 1 | Mar 1, 2017 | clinicaltrials |
| NCT00280475 | A Trial of Postoperative Whole Brain Radiation Therapy vs. Salvage Stereotactic Radiosurgery Therapy for Metastasis | completed | Phase 3 | 270 | Haruhiko FukudaOTHER | 1 | Sep 22, 2016 | clinicaltrials |
| NCT01620138 | Response to Cabergoline and Pasireotide in Non-functioning Pituitary Adenomas and Resistant Prolactinomas | completed | Phase 2 / Phase 3 | 21 | Universidade Federal do Rio de JaneiroOTHER | 1 | Aug 22, 2016 | clinicaltrials |
| NCT02636634 | Non Invasive Methods for Differential Diagnosis Radionecrosis/Recurrence After Radiosurgery of Brain Metastases(CV-METANEC) | completed | Phase 3 | 90 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Apr 11, 2016 | clinicaltrials |
| NCT00123760 | Study of 18F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Cancer or Suspected Cancer | completed | Phase 2 / Phase 3 | 10,838 | AHS Cancer Control AlbertaOTHER | 1 | Feb 25, 2016 | clinicaltrials |
| NCT00789828 | Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1)(EXIST-1) | completed | Phase 3 | 117 | Novartis PharmaceuticalsINDUSTRY | 10 | Feb 3, 2016 | clinicaltrials |
| NCT00681551 | Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Patients With Brain Metastasis | completed | Phase 3 | 45 | BayerINDUSTRY | 1 | Dec 15, 2014 | clinicaltrials |
| NCT00088166 | XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors | completed | Phase 3 | 200 | Celtic Pharma Development ServicesINDUSTRY | 2 | Aug 13, 2014 | clinicaltrials |
| NCT00002875 | Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma | completed | Phase 3 | 421 | Children's Oncology GroupNETWORK | 5 | Aug 1, 2014 | clinicaltrials |
| NCT00002944 | Combination Chemotherapy in Treating Children With Progressive Brain Tumors | completed | Phase 3 | 428 | Children's Oncology GroupNETWORK | 6 | Sep 9, 2013 | clinicaltrials |
| NCT00006461 | Combination Chemotherapy Followed by Second-Look Surgery and Radiation Therapy in Treating Children With Nonmetastatic Medulloblastoma or Primitive Neuroectodermal Tumor | completed | Phase 3 | 82 | Children's Oncology GroupNETWORK | 1 | Aug 9, 2013 | clinicaltrials |
| NCT00226655 | An Open-Labeled, Extended-Use of XERECEPT (hCRF) for Patients in Studies NTI 0302, 0303, or Other Designated Studies | completed | Phase 3 | 112 | Celtic Pharma Development ServicesINDUSTRY | 2 | Aug 31, 2012 | clinicaltrials |
| NCT00389883 | Anaesthesia for Supratentorial Tumor Resection | completed | Phase 3 | 69 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jul 10, 2012 | clinicaltrials |
| NCT01635140 | Hypofractionated Radiotherapy Versus Conventional Radiotherapy in Diffuse Brainstem Glioma in Children | completed | Phase 3 | 64 | Children's Cancer Hospital Egypt 57357OTHER | 1 | Jul 9, 2012 | clinicaltrials |
| NCT00241670 | Fluorescence-guided Resection of Malignant Gliomas With 5-Aminolevulinic Acid | completed | Phase 3 | 415 | medac GmbHINDUSTRY | 0 | Apr 26, 2012 | clinicaltrials |
| NCT00460395 | Surgery Versus Stereotactic Radiosurgery in the Treatment of Single Brain Metastasis: A Randomized Trial | completed | Phase 3 | 64 | M.D. Anderson Cancer CenterOTHER | 1 | Feb 24, 2012 | clinicaltrials |
| NCT00306683 | Effect of Diazoxide on the Obesity Secondary to Hypothalamic-pituitary Lesions | completed | Phase 3 | 40 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Feb 18, 2011 | clinicaltrials |
| NCT00124761 | A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases | completed | Phase 3 | 22 | Royal Adelaide HospitalOTHER | 1 | Sep 6, 2010 | clinicaltrials |
| NCT00181350 | Serial CT Scans in Fractionated Stereotactic Radiotherapy | completed | Phase 3 | 20 | Maastricht Radiation OncologyOTHER | 1 | Jun 30, 2009 | clinicaltrials |
| NCT00138788 | Brain Metastases Study: Radiotherapy Fractionation Schemes in the Treatment of Brain Metastases | completed | Phase 3 | 112 | St George Hospital, AustraliaOTHER | 1 | Nov 20, 2008 | clinicaltrials |
| NCT00054795 | Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART) | completed | Phase 3 | 550 | Pharmacyclics LLC.INDUSTRY | 8 | May 8, 2007 | clinicaltrials |
Data updated 4 days agoSource updated Sep 24, 2026source: clinicaltrials