Subtype
Bone Neoplasm
CI-CAN-00000569Explore in graph →
Non-malignant65 active trials4 approved drugs16 evidence items
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Subtype
CI-CAN-00000569Explore in graph →
Clinical trials
342 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04433221 | Combination Immunotherapy Targeting Sarcomas | not yet recruiting | Phase 1 / Phase 2 | 20 | Shenzhen Geno-Immune Medical InstituteOTHER | 1 | Aug 26, 2026 | clinicaltrials |
| NCT03965234 | Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases | recruiting | Phase 1 / Phase 2 | 99 | Roswell Park Cancer InstituteOTHER | 1 | Aug 21, 2026 | clinicaltrials |
| NCT05395741 | Regorafenib in Patients With Refractory Primary Bone Tumors(Regbone) | completed | Phase 1 / Phase 2 | 30 | Institute of Mother and Child, Warsaw, PolandOTHER | 1 | Aug 21, 2026 | clinicaltrials |
| NCT05621668 | A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma | active not recruiting | Phase 1 | 5 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 18, 2026 | clinicaltrials |
| NCT06008483 | A Dose Finding Study to Treat Bone Tumor(s) | terminated | Phase 1 | 5 | QSAM Therapeutics, Inc.INDUSTRY | 1 | Jul 23, 2026 | clinicaltrials |
| NCT00508443 | Evaluation of a Novel CT-On-Rails or Trilogy Stereotactic Spine Radiotherapy System (SSRS) | active not recruiting | Phase 1 / Phase 2 | 150 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT04616248 | In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors | active not recruiting | Phase 1 | 14 | University of Southern CaliforniaOTHER | 1 | Jun 18, 2026 | clinicaltrials |
| NCT03462316 | NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma | completed | Phase 1 | 2 | Sun Yat-sen UniversityOTHER | 1 | Jun 12, 2026 | clinicaltrials |
| NCT07197645 | Samarium Optimized for Long-lasting Analgesia in Cancerous End-stage Bone Pain(SOLACE) | recruiting | Phase 1 | 33 | Telix Pharmaceuticals (Innovations) Pty LimitedINDUSTRY | 1 | May 14, 2026 | clinicaltrials |
| NCT07560410 | Treatment of Truncated ALK-positive Bone Cancer Using Crizotinib (Xalkori) or Alectinib (Alecensa) | not yet recruiting | Phase 1 / Phase 2 | 10 | China Medical University HospitalOTHER | 1 | May 11, 2026 | clinicaltrials |
| NCT03420963 | Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors | terminated | Phase 1 | 12 | M.D. Anderson Cancer CenterOTHER | 1 | Mar 20, 2026 | clinicaltrials |
| NCT04420975 | Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma | active not recruiting | Phase 1 | 14 | Jonsson Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT06562673 | Intra-arterial Cisplatin Plus Rh-endostatin Combined With Systematic Chemotherapy in Osteosarcoma(IACE-OS) | completed | Phase 1 / Phase 2 | 10 | Shanghai 6th People's HospitalOTHER | 1 | Dec 29, 2025 | clinicaltrials |
| NCT02811523 | In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma | recruiting | Phase 1 | 17 | University Health Network, TorontoOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT00492817 | Evaluation of Single Session Stereotactic Body Radiotherapy | completed | Phase 1 / Phase 2 | 71 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 24, 2025 | clinicaltrials |
| NCT07066982 | Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas(BAH2573-103) | recruiting | Phase 1 / Phase 2 | 60 | Essen BiotechOTHER | 1 | Jul 15, 2025 | clinicaltrials |
| NCT06647901 | Efficacy of ICG-based NIR Imaging in Intralesional Curettage of Giant Cell Tumors of Bone in Limbs: a Prospective, Single-center, Single-arm, Open Study | recruiting | Phase 1 / Phase 2 | 45 | Tang XiaodongOTHER | 1 | Oct 18, 2024 | clinicaltrials |
| NCT03277924 | Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas(ImmunoSarc) | completed | Phase 1 / Phase 2 | 197 | Grupo Espanol de Investigacion en SarcomasOTHER | 3 | Aug 13, 2024 | clinicaltrials |
| NCT01803152 | Dendritic Cell Vaccine for Children and Adults With Sarcoma | completed | Phase 1 | 19 | Macarena De La Fuente, MDOTHER | 1 | Jul 3, 2024 | clinicaltrials |
| NCT00019630 | Liposomal Doxorubicin in Treating Children With Refractory Solid Tumors | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00020267 | Vaccine Therapy in Treating Patients With Metastatic Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT04310410 | Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis(PRE-FURTHER) | completed | Phase 1 / Phase 2 | 10 | UMC UtrechtOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT03525392 | Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1. | terminated | Phase 1 | 14 | IpsenINDUSTRY | 5 | Dec 12, 2023 | clinicaltrials |
| NCT04255576 | Efficacy and Safety of JMT103 in Patients With Giant Cell Tumor of Bone | unknown | Phase 1 / Phase 2 | 139 | Shanghai JMT-Bio Inc.INDUSTRY | 1 | Oct 14, 2022 | clinicaltrials |
| NCT02398058 | Trabectedin Plus Olaparib in Metastatic or Advanced Sarcomas (TOMAS)(TOMAS) | completed | Phase 1 | 50 | Italian Sarcoma GroupNETWORK | 1 | Apr 14, 2021 | clinicaltrials |
| NCT04798326 | Comparing of the Pharmacokinetic, Pharmacodynamic, Safety and Immunogenicity of MW032 and Xgeva® in Healthy Adults(MW032) | completed | Phase 1 | 120 | Mabwell (Shanghai) Bioscience Co., Ltd.INDUSTRY | 1 | Mar 15, 2021 | clinicaltrials |
| NCT04178044 | Phase Ⅰ Clinical Study Protocol of GB223 Monoclonal Antibody Injection | unknown | Phase 1 | 44 | Genor Biopharma Co., Ltd.INDUSTRY | 1 | Nov 26, 2019 | clinicaltrials |
| NCT02274623 | Effect of CTAP101 Capsules on Ca/iPTH in Advanced Breast/Prostate Cancer Patients Treated With Denosumab/Zoledronic Acid | completed | Phase 1 | 33 | OPKO Health, Inc.INDUSTRY | 1 | Sep 27, 2019 | clinicaltrials |
| NCT03066245 | Use of Stem Cells Cultured on a Scaffold for the Treatment of Aneurysmal Bone Cysts (ABC) | unknown | Phase 1 / Phase 2 | 4 | Sophia Al-AdwanOTHER | 1 | Jul 24, 2019 | clinicaltrials |
| NCT00960063 | A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006) | terminated | Phase 1 | 4 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Aug 27, 2018 | clinicaltrials |
| NCT00931931 | HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors | completed | Phase 1 | 18 | Timothy CripeOTHER | 1 | Mar 21, 2018 | clinicaltrials |
| NCT03415477 | Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts(Deno-ABC) | completed | Phase 1 / Phase 2 | 6 | Peking University People's HospitalOTHER | 0 | Jan 30, 2018 | clinicaltrials |
| NCT02303366 | Pilot Study of Stereotactic Ablation for Oligometastatic Breast Neoplasia in Combination With the Anti-PD-1 Antibody MK-3475(BOSTON II) | completed | Phase 1 | 15 | Peter MacCallum Cancer Centre, AustraliaOTHER | 1 | Oct 18, 2017 | clinicaltrials |
| NCT00450736 | Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery | completed | Phase 1 | 3 | University of MiamiOTHER | 1 | Dec 15, 2016 | clinicaltrials |
| NCT02862288 | Preliminary Study of Microwave Tumoral Ablation Performances for the Treatment of Pulmonary, Renal and Bone Neoplasia.(TherMO) | completed | Phase 1 / Phase 2 | 30 | Centre Hospitalier Universitaire de BesanconOTHER | 1 | Aug 11, 2016 | clinicaltrials |
| NCT00720174 | Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma | completed | Phase 1 | 30 | National Cancer Institute (NCI)NIH | 1 | May 17, 2016 | clinicaltrials |
| NCT01564121 | Study of the Effect of Zoledronate on Local Recurrence After Surgical Treatment of Giant Cell Tumors of Bone Zométa(Zometa) | terminated | Phase 1 / Phase 2 | 24 | Nantes University HospitalOTHER | 1 | Aug 30, 2013 | clinicaltrials |
| NCT00168129 | Helical Tomotherapy as a Radiotherapy Technique for Treating Bone Metastases | completed | Phase 1 | 10 | Alberta Health servicesOTHER | 1 | Dec 9, 2011 | clinicaltrials |
| NCT00423254 | Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer. | completed | Phase 1 | 12 | Mannkind CorporationINDUSTRY | 1 | Aug 3, 2010 | clinicaltrials |
Data updated 22 days agoSource updated Aug 26, 2026source: clinicaltrials