Subtype
Adrenal Cortical Neoplasm
CI-CAN-00001700Explore in graph →
Non-malignant26 active trials1 approved drugs2 evidence items
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Subtype
CI-CAN-00001700Explore in graph →
Clinical trials
105 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00304070 | Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor | completed | Phase 3 | 78 | Children's Oncology GroupNETWORK | 4 | Feb 28, 2024 | clinicaltrials |
| NCT04373265 | Study of Relacorilant in Combination With Pembrolizumab for Patients With Adrenocortical Carcinoma Which Produces Too Much Stress Hormone (Cortisol) | completed | Phase 1 | 15 | Corcept TherapeuticsINDUSTRY | 1 | Feb 23, 2024 | clinicaltrials |
| NCT06050057 | Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy | unknown | — | 100 | University Hospital OlomoucOTHER | 1 | Sep 22, 2023 | clinicaltrials |
| NCT05991856 | Multifaceted Comparison of Ultrasound-guided Ablation and Laparoscopic Adrenalectomy for Aldosterone-producing Adenoma | recruiting | — | 45 | Third Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 1 | Aug 15, 2023 | clinicaltrials |
| NCT05839886 | The Adverse Event of Mitotane Therapy in Patients With Adrenocortical Carcinoma(MEET) | unknown | — | 50 | Shanghai Jiao Tong University School of MedicineOTHER | 0 | May 6, 2023 | clinicaltrials |
| NCT05763524 | European Multicenter Study on Role of Lymph Node Dissection in Surgical Management of Adrenal Cortical Carcinoma(LACC) | unknown | — | 90 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 20, 2023 | clinicaltrials |
| NCT05344027 | The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma(MitoS-FP) | completed | — | 35 | King's College Hospital NHS TrustOTHER | 1 | Mar 8, 2023 | clinicaltrials |
| NCT04447014 | Natural History Study of Children and Adults With Adrenocortical Cancer (ACC) | terminated | — | 15 | National Cancer Institute (NCI)NIH | 1 | Jan 17, 2023 | clinicaltrials |
| NCT05660889 | Adrenal Vein Sampling as a Tool to Identify Biomarkers That Aid the Diagnosis of Adrenocortical Carcinoma(AVS for ACC) | unknown | — | 25 | Erasmus Medical CenterOTHER | 1 | Dec 21, 2022 | clinicaltrials |
| NCT05361083 | First-in-human Evaluation of [18F]CETO | completed | Early Phase 1 | 20 | Uppsala UniversityOTHER | 1 | May 4, 2022 | clinicaltrials |
| NCT02637531 | A Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549 | unknown | Phase 1 | 219 | Infinity Pharmaceuticals, Inc.INDUSTRY | 1 | Apr 4, 2022 | clinicaltrials |
| NCT04890444 | China Adrenal Disease Registry(CASE) | unknown | — | 2,000 | Shanghai Jiao Tong University School of MedicineOTHER | 1 | Feb 14, 2022 | clinicaltrials |
| NCT04666220 | VETC, Prognostic and Predictive Value in Renal Cell Carcinoma and Adrenal Carcinoma | unknown | — | 180 | Humanitas Clinical and Research CenterOTHER | 1 | Feb 12, 2021 | clinicaltrials |
| NCT02468193 | Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome | completed | Phase 2 | 9 | Novartis PharmaceuticalsINDUSTRY | 1 | May 6, 2020 | clinicaltrials |
| NCT03474237 | A Prospective Cohort Study for Patients With Adrenal Diseases | enrolling by invitation | — | 1,500 | Seoul National University HospitalOTHER | 1 | Mar 18, 2020 | clinicaltrials |
| NCT02015026 | Natural History and Tissue Acquisition Study of Adrenocortical Carcinoma | completed | — | 67 | National Cancer Institute (NCI)NIH | 1 | Dec 12, 2019 | clinicaltrials |
| NCT03830593 | Laparoscopic Adrenalectomy for Large Adrenal Tumors. | completed | — | 102 | Samsun Liv HospitalOTHER | 1 | Oct 10, 2019 | clinicaltrials |
| NCT01833832 | Surgery and Heated Chemotherapy for Adrenocortical Carcinoma | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | Jul 30, 2019 | clinicaltrials |
| NCT02720484 | Nivolumab in Treating Patients With Metastatic Adrenocortical Cancer | terminated | Phase 2 | 10 | Northwestern UniversityOTHER | 1 | May 1, 2019 | clinicaltrials |
| NCT00453895 | Sunitinib in Refractory Adrenocortical Carcinoma(SIRAC) | completed | Phase 2 | 39 | University of WuerzburgOTHER | 1 | Jan 31, 2019 | clinicaltrials |
| NCT02747355 | Expression of Different Proliferation Biomarkers in Adreno-cortical Tumors | unknown | — | 70 | Bnai Zion Medical CenterOTHER_GOV | 0 | Jan 18, 2019 | clinicaltrials |
| NCT01262235 | A Dose Finding Study of TKM-080301 Infusion in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients | completed | Phase 1 / Phase 2 | 68 | Arbutus Biopharma CorporationINDUSTRY | 1 | Jan 16, 2019 | clinicaltrials |
| NCT03517332 | Circulating Tumor DNA Exposure in Peripheral Blood | unknown | — | 10,000 | Quantgene Inc.INDUSTRY | 2 | Nov 20, 2018 | clinicaltrials |
| NCT00003453 | Antineoplaston Therapy in Treating Patients With Stage IV Adrenal Gland Cancer | terminated | Phase 2 | 6 | Burzynski Research InstituteOTHER | 1 | May 9, 2018 | clinicaltrials |
| NCT03257891 | Cabazitaxel Activity in Patients With Advanced AdrenoCortical-Carcinoma Progressing After Previous Chemotherapy Lines(CabACC) | unknown | Phase 2 | 25 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaOTHER | 1 | Apr 11, 2018 | clinicaltrials |
| NCT01898715 | Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma | completed | Phase 1 | 63 | Millendo Therapeutics, Inc.INDUSTRY | 2 | Nov 6, 2017 | clinicaltrials |
| NCT02831179 | Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor | withdrawn | Phase 1 | 0 | Vanderbilt-Ingram Cancer CenterOTHER | 0 | Sep 28, 2017 | clinicaltrials |
| NCT03145285 | Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma(ABACUS) | unknown | Phase 2 | 10 | Azienda Socio Sanitaria Territoriale degli Spedali Civili di BresciaOTHER | 1 | May 10, 2017 | clinicaltrials |
| NCT00777244 | Efficacy of Adjuvant Mitotane Treatment (ADIUVO)(ADIUVO) | unknown | Phase 3 | 200 | University of Turin, ItalyOTHER | 7 | May 8, 2017 | clinicaltrials |
| NCT01514526 | Clinical Trial of Dovitinib in First-line Metastatic or Locally Advanced Non-resectable Adrenocortical Carcinoma | completed | Phase 2 | 17 | Spanish Oncology Genito-Urinary GroupOTHER | 1 | Apr 25, 2017 | clinicaltrials |
| NCT02030587 | Laparoscopic Adrenalectomy Versus Radiofrequency Ablation(LARFA) | unknown | N/A | 36 | Chinese University of Hong KongOTHER | 1 | Apr 25, 2017 | clinicaltrials |
| NCT00445718 | Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging | completed | — | 97 | Children's Oncology GroupNETWORK | 3 | Feb 9, 2017 | clinicaltrials |
| NCT02150213 | Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492 | completed | Phase 2 | 59 | Novartis PharmaceuticalsINDUSTRY | 6 | Dec 5, 2016 | clinicaltrials |
| NCT00094497 | Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT) | completed | Phase 3 | 304 | Collaborative Group for Adrenocortical Carcinoma TreatmentOTHER | 8 | Sep 21, 2016 | clinicaltrials |
| NCT01528956 | Studying Genes in Samples From Younger Patients With Adrenocortical Tumor | completed | — | 10 | Children's Oncology GroupNETWORK | 0 | May 18, 2016 | clinicaltrials |
| NCT01832974 | Possible New Therapy for Advanced Cancer | terminated | Phase 1 | 9 | INSYS Therapeutics IncINDUSTRY | 1 | Apr 27, 2015 | clinicaltrials |
| NCT00469469 | Treatment Study Using Bevacizumab for Patients With Adrenocortical Carcinoma | withdrawn | Phase 2 | 0 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Apr 22, 2015 | clinicaltrials |
| NCT00831844 | Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors | completed | Phase 2 | 116 | National Cancer Institute (NCI)NIH | 3 | Mar 30, 2015 | clinicaltrials |
| NCT00848016 | Gossypol Acetic Acid in Treating Patients With Recurrent, Metastatic, or Primary Adrenocortical Cancer That Cannot Be Removed By Surgery | completed | Phase 2 | 29 | National Cancer Institute (NCI)NIH | 1 | May 7, 2014 | clinicaltrials |
| NCT00778817 | IMC-A12 With Mitotane vs Mitotane Alone in Recurrent, Metastatic, or Primary ACC That Cannot Be Removed by Surgery | terminated | Phase 2 | 20 | National Cancer Institute (NCI)NIH | 1 | Apr 29, 2014 | clinicaltrials |
| NCT01048892 | Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features | completed | Phase 1 | 22 | Children's Oncology GroupNETWORK | 1 | Jan 30, 2014 | clinicaltrials |
| NCT00002608 | Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors | completed | Phase 2 | 30 | Ottawa Regional Cancer CentreOTHER | 1 | Jul 10, 2013 | clinicaltrials |
| NCT01255137 | Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-Pathway in Metastatic, Recurrent or Primary Unresectable Adrenocortical Cancer | completed | Phase 2 | 13 | National Cancer Institute (NCI)NIH | 1 | Jun 27, 2013 | clinicaltrials |
| NCT00091182 | Oxaliplatin in Treating Young Patients With Recurrent Solid Tumors That Have Not Responded to Previous Treatment | completed | Phase 2 | 180 | National Cancer Institute (NCI)NIH | 1 | Jun 5, 2013 | clinicaltrials |
| NCT00004074 | Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neu | completed | Phase 1 | 15 | National Cancer Institute (NCI)NIH | 1 | Feb 28, 2013 | clinicaltrials |
| NCT00002921 | S9427, Suramin in Treating Patients With Stage III or Stage IV Adrenocortical Cancer Incurable by Surgery | terminated | Phase 2 | 13 | SWOG Cancer Research NetworkNETWORK | 1 | Oct 5, 2012 | clinicaltrials |
| NCT00071058 | Surgery Plus Chemotherapy (Doxorubicin, Vincristine and Etoposide), Mitotane, and Tariquidar to Treat Adrenocortical Cancer | completed | Phase 2 | 50 | National Cancer Institute (NCI)NIH | 1 | Sep 18, 2012 | clinicaltrials |
| NCT00436410 | Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer | completed | Early Phase 1 | 108 | National Institutes of Health Clinical Center (CC)NIH | 1 | May 2, 2012 | clinicaltrials |
| NCT00436657 | Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer | completed | Phase 1 | 10 | M.D. Anderson Cancer CenterOTHER | 1 | Apr 2, 2012 | clinicaltrials |
| NCT00324012 | Trial With Taxotere and Cisplatin in Non-operable Adrenocortical Carcinoma | completed | Phase 2 | 19 | Rigshospitalet, DenmarkOTHER | 1 | Feb 22, 2012 | clinicaltrials |
Data updated 22 days agoSource updated Feb 28, 2024source: clinicaltrials