Clinical trial · Observational
Laparoscopic Adrenalectomy for Large Adrenal Tumors.
Is There Anything New in the Field of Large Adrenal Tumors ?
NCT03830593CI-TRIAL-00041083completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Laparoscopic adrenalectomy is the treatment of choice for the benign tumor of less than 6 cm. However, this is an ongoing debate that exact cut-off value of tumor size for LA. The aim of this study was to assess whether the size of the adrenal tumor affects preoperative and postoperative outcomes in patients undergoing laparoscopic transperitoneal adrenalectomy as well as to evaluate the learning curve.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adrenal Adenoma | Adrenal Cortical Adenoma | ALIAS | 0.90 |
| Adrenal Tumor | Adrenal Gland Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic Adrenalectomy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- label
- Group 1
- description
- laparoscopic adrenalectomy group 1: tumor size as \< 6 (group1)
- interventionNames
- Procedure: Laparoscopic Adrenalectomy
- label
- Group 2
- description
- Laparoscopic adrenalectomy group2: tumor size ≥ 6 cm (group2)
- interventionNames
- Procedure: Laparoscopic Adrenalectomy
- label
- Learning Curve
- description
- The patients, underwent laparoscopic adrenalectomy, were also classified into group A (1-25), B (26-50), C (51-75), and D (76-102) according to the chronological order of their surgery in order to evaluate the learning curve.
- interventionNames
- Procedure: Laparoscopic Adrenalectomy
Primary outcomes (4)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. all hormonally active adrenal lesions, 2. detection of increases in size in \< 4 cm adrenal tumors on serial imaging, 3. solitary adrenal metastases without evidence of local invasion, 4. tumors size ≥ 4 cm, 5. patients between the age of 18 and 80 6. American Society of Anesthesiologists score (ASA) ≤ 3. Exclusion Criteria: 1. suspicion of malignancy on imaging such as local invasion, irregular tumor margins 2. Retroperitoneoscopic adrenalectomies 3. laparoscopic partial adrenalectomies
References
Publications (2)
- BACKGROUNDHuynh KT, Lee DY, Lau BJ, Flaherty DC, Lee J, Goldfarb M. Impact of Laparoscopic Adrenalectomy on Overall Survival in Patients with Nonmetastatic Adrenocortical Carcinoma. J Am Coll Surg. 2016 Sep;223(3):485-92. doi: 10.1016/j.jamcollsurg.2016.05.015. Epub 2016 May 26. PMID 27238874
- RESULTConzo G, Gambardella C, Candela G, Sanguinetti A, Polistena A, Clarizia G, Patrone R, Di Capua F, Offi C, Musella M, Iorio S, Bellastella G, Pasquali D, De Bellis A, Sinisi A, Avenia N. Single center experience with laparoscopic adrenalectomy on a large clinical series. BMC Surg. 2018 Jan 11;18(1):2. doi: 10.1186/s12893-017-0333-8. PMID 29325527