Clinical trial · Interventional
Laparoscopic Adrenalectomy Versus Radiofrequency Ablation
Laparoscopic Adrenalectomy Versus Radiofrequency Ablation for Aldosterone-producing Adenoma: a Prospective Randomized Controlled Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective randomized controlled study comparing laparoscopic adrenalectomy (LA) versus image-guided percutaneous radiofrequency ablation (RFA) in treating aldosterone-producing adenoma. The objectives of this study are to 1. compare the short-term outcomes of LA and RFA in treating aldosterone-producing adenoma. 2. compare the treatment success rates of LA and RFA during follow-up for primary aldosteronism.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Adrenocortical Adenoma | Adrenal Cortical Adenoma | ALIAS | 0.90 |
| Conn Syndrome | — | UNRESOLVED | — |
| Hyperaldosteronism | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Laparoscopic Adrenalectomy | Procedure | — | UNRESOLVED |
| Radiofrequency Ablation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Radiofrequency Ablation
- description
- Radiofrequency Ablation
- interventionNames
- Procedure: Radiofrequency Ablation
- type
- ACTIVE_COMPARATOR
- label
- Laparoscopic Adrenalectomy
- description
- Laparoscopic Adrenalectomy
- interventionNames
- Procedure: Laparoscopic Adrenalectomy
Primary outcomes (2)
- measure
- Morbidity rate
- timeFrame
- 30-day
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
- Maximum age
- 80 Years
Show eligibility criteria text
Inclusion Criteria: 1. Hypertensive individuals 2. Biochemically confirmed primary aldosteronism 3. Radiologically confirmed unilateral adrenal adenoma ≤3cm Exclusion Criteria: 1. Bilateral adrenal disease 2. Multiple adrenal tumors 3. Other concomitant adrenal diseases 4. Potentially malignant adrenal tumors as shown on imaging 5. Uncorrected coagulopathy 6. Surgically unfit for general anaesthesia 7. Prior open abdominal surgery
References
Publications (1)
- BACKGROUNDLiu SY, Ng EK, Lee PS, Wong SK, Chiu PW, Mui WL, So WY, Chow FC. Radiofrequency ablation for benign aldosterone-producing adenoma: a scarless technique to an old disease. Ann Surg. 2010 Dec;252(6):1058-64. doi: 10.1097/SLA.0b013e318f66936. PMID 21107117