Hematologic Malignancy
Acute Leukemia
CI-CAN-00000399Explore in graph →
Hematologic1,255 active trials30 approved drugs323 evidence items
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Hematologic Malignancy
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Clinical trials
4,656 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (723)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06429449 | Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemia | recruiting | Phase 1 | 30 | University of Colorado, DenverOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT07342244 | Safety and Efficacy of CLL1 CAR-T Followed by Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia | not yet recruiting | N/A | 18 | Donghua ZhangOTHER | 1 | Jan 15, 2026 | clinicaltrials |
| NCT07343687 | Clinico-hematological and Coagulation Profiles in Newly Diagnosed Acute Myeloid Leukemia Patients Treated With Intensive Induction Chemotherapy . | not yet recruiting | — | 80 | Assiut UniversityOTHER | 0 | Jan 15, 2026 | clinicaltrials |
| NCT05942599 | Base Edited CAR T Cells Against AML: Deep Conditioning Ahead of Allogeneic Stem Cell Transplantation(CARAML) | active not recruiting | Phase 1 | 10 | Great Ormond Street Hospital for Children NHS Foundation TrustOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT06572982 | Extension Study, Pilot, Compassionate Use of Azacitidine 300 mg Film Coated Tablets for Acute Myeloid Leukaemia (AML) Patients | active not recruiting | N/A | 20 | Hikma Pharmaceuticals LLCINDUSTRY | 1 | Jan 14, 2026 | clinicaltrials |
| NCT03121014 | Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes | active not recruiting | Phase 2 | 38 | University of Illinois at ChicagoOTHER | 1 | Jan 13, 2026 | clinicaltrials |
| NCT05317403 | Venetoclax to Augment Epigenetic Modification and Chemotherapy | recruiting | Phase 1 | 40 | Medical College of WisconsinOTHER | 1 | Jan 12, 2026 | clinicaltrials |
| NCT04203316 | Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation | active not recruiting | Phase 2 | 1 | Children's Oncology GroupNETWORK | 2 | Jan 9, 2026 | clinicaltrials |
| NCT04686682 | A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors | recruiting | Phase 1 / Phase 2 | 152 | Jacobio Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Jan 9, 2026 | clinicaltrials |
| NCT04872478 | Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL | recruiting | Phase 1 | 50 | Meryx, Inc.INDUSTRY | 1 | Jan 8, 2026 | clinicaltrials |
| NCT04928599 | Financial Distress During Treatment for Pediatric Acute Lymphoblastic Leukemia in the United States | active not recruiting | — | 100 | Children's Oncology GroupNETWORK | 2 | Jan 8, 2026 | clinicaltrials |
| NCT05342584 | Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS(Venetoclax AML) | recruiting | Phase 1 | 99 | Montefiore Medical CenterOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT05597306 | Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia(VenBom) | recruiting | Phase 1 | 18 | Terrence J Bradley, MDOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT07326930 | Tracjectories and Predictors of Chemotherapy Induced Peripheral Neuropathy in Children With Acute Lymphoblastic Leukemia | recruiting | — | 173 | The Hong Kong Polytechnic UniversityOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT07327138 | Children's Laughter and Fun Yoga as Adjunctive Pain Relief Following Chemotherapy.(CLAP) | recruiting | N/A | 60 | Bahaa Bou DarghamOTHER | 1 | Jan 8, 2026 | clinicaltrials |
| NCT03481881 | Pharmacokinetics of Drugs Administered to Children | recruiting | — | 200 | Duke UniversityOTHER | 1 | Jan 7, 2026 | clinicaltrials |
| NCT03674411 | Trial Evaluating MGTA-456 in Patients With High-Risk Malignancy | active not recruiting | Phase 2 | 22 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT06514768 | JY231 (JY231) Injection for the Treatment of B-cell Acute Lymphoblastic Leukemia (B-ALL) | recruiting | Early Phase 1 | 20 | 920th Hospital of Joint Logistics Support Force of People's Liberation Army of ChinaOTHER | 1 | Jan 6, 2026 | clinicaltrials |
| NCT07319793 | Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT | not yet recruiting | N/A | 200 | Peking University People's HospitalOTHER | 0 | Jan 6, 2026 | clinicaltrials |
| NCT01252485 | Registry Study on Patient Characteristics, Biological Disease Profile and Clinical Outcome in Acute Myeloid Leukemia and Related Neoplasms - The Biology and Outcome (BiO)-Project(AMLSG BiO) | recruiting | — | 50,000 | University of UlmOTHER | 2 | Jan 5, 2026 | clinicaltrials |
| NCT01853631 | Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)(SAGAN) | recruiting | Phase 1 | 64 | Baylor College of MedicineOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT03912064 | A Phase 1 Trial of CD25/Treg-depleted DLI Plus Ipilimumab for Myeloid Disease Relapse After Matched-HCT | active not recruiting | Phase 1 | 25 | Dana-Farber Cancer InstituteOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05184842 | Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML | recruiting | Phase 2 | 91 | Montefiore Medical CenterOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT05199051 | A Phase 2 Study of Gemtuzumab Ozogamicin (GO)-Gilteritinib Combination in Adults With FLT3-ITD and/or FLT3-TKD Relapse/Refractory (R/R) AML(AGORA-1) | active not recruiting | Phase 2 | 19 | Centre Antoine LacassagneOTHER | 1 | Jan 5, 2026 | clinicaltrials |
| NCT07313878 | Evaluation of Acute and Chronic Nephrotoxicity in Acute Lymphatic Leukemia Patients Using Ultrasound Localization Microscopy(HEALED) | recruiting | N/A | 30 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Jan 2, 2026 | clinicaltrials |
| NCT06452732 | Using Multiparametric Flow Cytometry to Detect Peripheral Blood and Bone Marrow Leukaemia Stem Cells for Relapse Prediction in P-AML | recruiting | — | 283 | Peking University People's HospitalOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT07312630 | Clinical Study of LV009 Injection for the Treatment of Relapsed/Refractory CD19-Positive Hematologic and Lymphoid Malignancies | recruiting | Early Phase 1 | 19 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 31, 2025 | clinicaltrials |
| NCT07297576 | Safety and Feasibility of Sulforaphane to Promote Early Haematopoietic Recovery After Cord Blood Transplantation | recruiting | N/A | 36 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Dec 30, 2025 | clinicaltrials |
| NCT05657639 | CAV Regimen for R/R AML | recruiting | Phase 2 | 68 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Dec 29, 2025 | clinicaltrials |
| NCT05657652 | CAV Regimen for R/R Ph- B-ALL | recruiting | N/A | 36 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Dec 29, 2025 | clinicaltrials |
| NCT07296445 | A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301)(LATITUDE) | not yet recruiting | Phase 3 | 120 | SDK Therapeutics, Inc.INDUSTRY | 0 | Dec 29, 2025 | clinicaltrials |
| NCT07304232 | Post-transplantation Maintenance Therapy With Cidabenamide in Patients With Intermediate/High-risk AML(CM-AML-001) | recruiting | Phase 2 | 134 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Dec 26, 2025 | clinicaltrials |
| NCT07300683 | Anti-CCR9 CAR T Cells for T Cell Leukaemia/Lymphoma(FRACTALL) | recruiting | Phase 1 | 24 | University College, LondonOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT07301138 | BEBT-908 Plus Chemotherapy Treatment for CR MRD-Positive MEF2D-Rearranged and Pre-B Acute Lymphoblastic Leukemia Patients | not yet recruiting | Phase 2 | 23 | Ruijin HospitalOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT07301866 | A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe.(ECT-001-CB-013) | recruiting | Phase 1 / Phase 2 | 7 | Ciusss de L'Est de l'Île de MontréalOTHER | 1 | Dec 24, 2025 | clinicaltrials |
| NCT05105152 | PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML | recruiting | Phase 1 | 18 | Seattle Children's HospitalOTHER | 1 | Dec 23, 2025 | clinicaltrials |
| NCT07297914 | Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALL(FORUM2) | not yet recruiting | Phase 2 / Phase 3 | 1,000 | Bambino Gesù Hospital and Research InstituteOTHER | 9 | Dec 22, 2025 | clinicaltrials |
| NCT06387121 | Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL | recruiting | Phase 2 | 53 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT05901974 | Venetoclax Combined With Azactidine in the Treatment of ALAL | recruiting | Phase 2 | 23 | Sheng-Li Xue, MDOTHER | 1 | Dec 16, 2025 | clinicaltrials |
| NCT06552416 | Safety of MT-401-OTS in Patients With Relapsed AML or MDS(RAPID) | recruiting | Phase 1 | 40 | Marker Therapeutics, Inc.INDUSTRY | 1 | Dec 16, 2025 | clinicaltrials |
| NCT07121140 | Home Blood Transfusions | recruiting | N/A | 30 | Thomas Jefferson UniversityOTHER | 1 | Dec 16, 2025 | clinicaltrials |
| NCT07284927 | Clinical Study of LV009 Injection for the Treatment of Hematologic and Lymphoid Malignancies | recruiting | Phase 1 | 10 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 16, 2025 | clinicaltrials |
| NCT07153068 | SupCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies | recruiting | Phase 1 / Phase 2 | 12 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Dec 15, 2025 | clinicaltrials |
| NCT07277504 | Autologous Bedside CD19 CAR T-cell Therapy for B-ALL | not yet recruiting | Early Phase 1 | 50 | The General Hospital of Western Theater CommandOTHER | 1 | Dec 11, 2025 | clinicaltrials |
| NCT06680752 | Clinical Study of ARD103 CAR-T Therapy for Patients With R/R AML or MDS | recruiting | Phase 1 / Phase 2 | 49 | ARCE Therapeutics, Inc.INDUSTRY | 1 | Dec 10, 2025 | clinicaltrials |
| NCT07269587 | A Real-world Study on the Treatment of Adult B-cell Acute Lymphoblastic Leukemia With CNCT-19 | active not recruiting | — | 275 | Ruijin HospitalOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT03828773 | PTX3-targeted Antifungal Prophylaxis(PTX3AML) | recruiting | N/A | 410 | Bochud Pierre-YvesOTHER | 3 | Dec 9, 2025 | clinicaltrials |
| NCT04167683 | Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant | active not recruiting | — | 144 | Rigshospitalet, DenmarkOTHER | 1 | Dec 8, 2025 | clinicaltrials |
| NCT06782971 | Evaluation of Combined Sensitising and Hypomethylating Therapy Outcomes in AML PDX(COSMOS-Avatar) | recruiting | — | 25 | Clinical Hub for Interventional Research (CHOIR)OTHER_GOV | 1 | Dec 8, 2025 | clinicaltrials |
| NCT06906380 | A Long-term Follow-up Study of Patients With ARD103 CAR-T Cell Therapies | not yet recruiting | — | 49 | ARCE Therapeutics, Inc.INDUSTRY | 1 | Dec 8, 2025 | clinicaltrials |
Data updated 24 days agoSource updated Jan 15, 2026source: clinicaltrials