Variant · Fusion
ZNF384 Fusion
CI-VAR-00001471Explore in graph →CIViC 5187
Curated evidence
Evidence by cancer (3 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 33692463
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| B-lymphoblastic Leukaemia/lymphoma With Other Defined Genetic Alterations3unmapped disease | ||||||||
| v::ZNF384 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 3 | accepted | EID12440In this retrospective multicenter study, 218 patients diagnosed with B-lymphoblastic leukemia/lymphoma (B-ALL) harboring ZNF384 rearrangements were analyzed between 1992 and 2018 across 16 internation… (full text at CIViC) PMID 33692463 · Hirabayashi et al., 2021 · Open in CIViC | civic |
| v::ZNF384 Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 3 | accepted | EID12442In this study, the authors investigated a targeted diagnostic approach to identify ZNF384 rearrangements in B-lymphoblastic leukemia/lymphoma (B-ALL) based on immunophenotypic features. Since ZNF384 … (full text at CIViC) PMID 33988307 · Janet et al., 2021 · Open in CIViC | |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available