SRF Fusion

CI-VAR-00001481Explore in graph →CIViC 5209

Curated evidence

Evidence by cancer (4 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–4 of 4 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Myofibroma And Myopericytoma4unmapped disease
SRF::v Fusion	(diagnostic)	Diagnostic	B	Supports Positive	4	accepted	EID12517 In this 2017 study the author included 44 cellular myofibroblastic tumors previously diagnosed as cellular myofibroma, cellular myopericytoma, or cellular myofibroblastic neoplasms (NOS), and a contro… (full text at CIViC) PMID 28248815 · Antonescu et al., 2017 · Open in CIViC	civic
SRF::v Fusion	(diagnostic)	Diagnostic	B	Supports Positive	4	accepted	EID12518 In this 2020 study, the authors include 13 perivascular myoid tumors belonging to the previously described SRF rearranged subtype of tumors (PMID:28248815), which share morphologic features with myope… (full text at CIViC) PMID 33021523 · Karanian et al., 2020 · Open in CIViC

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.