PPP2R1A P179R

CI-VAR-00003304Explore in graph →CIViC 3299

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Unmapped disease1unmapped disease
PPP2R1A P179R	(functional)	Functional	D	Supports Loss Of Function	4	accepted	EID9212 Immunoprecipitation experiments in a serous endometrial carcinoma cell line that expressed V5 tagged PPP2R1A P179R protein revealed that binding of PPP2R1A to the PP2A holoenzyme complex members was s… (full text at CIViC) PMID 31142515 · Taylor et al., 2019 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.