FLT3 S963L

CI-VAR-00004150Explore in graph →CIViC 5562

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Malignant Mesothelioma1
FLT3 S963L	(oncogenic)	Oncogenic	C	Does Not Support Oncogenicity	1	submitted	EID13209 FFPE samples from 11 malignant mesothelioma patients were sequenced. In one patient, who was 63 and F, with Epithelioid subtype and Pleural origin, FLT3 S963L was found, together with BCL6 R459C, EP30… (full text at CIViC) PMID 27127140 · Ugurluer et al., 2016 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.