EWSR1 Fusion

CI-VAR-00001516Explore in graph →CIViC 5450

Curated evidence

Evidence by cancer (4 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–4 of 4 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Myoepithelial Tumor4
EWSR1::v Fusion	(diagnostic)	Diagnostic	B	Supports Positive	3	accepted	EID12926 The authors performed retrospective analysis of 66 myoepithelial (ME) tumors arising outside the salivary glands, including soft tissue, bone, and visceral lesions. The cohort included 36 females and … (full text at CIViC) PMID 20815032 · Antonescu et al., 2010 · Open in CIViC	civic
EWSR1::v Fusion	(diagnostic)	Diagnostic	B	Supports Positive	3	accepted	EID12927 In this 2024 study, the authors analyzed 40 myoepithelial tumors of soft tissue and bone arising in patients ≤21 years of age. The cohort included 22 females and 18 males, with ages ranging from 3 mon… (full text at CIViC) PMID 38782103 · Logan et al., 2024 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.