CREB3L1 Fusion

CI-VAR-00001419Explore in graph →CIViC 4974

Curated evidence

Evidence by cancer (3 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–3 of 3 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Sclerosing Epithelioid Fibrosarcoma3
EWSR1::CREB3L1 Fusion	(diagnostic)	Diagnostic	B	Supports Positive	3	accepted	EID12058 In this 2017 study, the authors utilized SNP arrays, expression profiling, transcriptome, and whole-exome sequencing to further characterize sclerosing epithelioid fibrosarcoma (SEF) and low-grade fi… (full text at CIViC) PMID 28939748 · Arbajian et al., 2017 · Open in CIViC	civic
EWSR1::CREB3L1 Fusion	(diagnostic)	Diagnostic	C	Supports Positive	3	accepted	EID12057 In this 2014 study, the authors compared 10 primary sclerosing epithelioid fibrosarcomas (SEF), 4 cases of low-grade fibromyxoid sarcoma (LGFMS), and one primary hybrid SEF/LGFMS. Patients with SEF ra… (full text at CIViC) PMID 24441665 · Arbajian et al., 2014 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.