Variant · Fusion
WIF1 Fusion
CI-VAR-00001355Explore in graph →CIViC 4344
Curated evidence
Evidence by cancer (1 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26762204
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| IDH-wildtype Glioblastoma1unmapped disease | ||||||||
| EGFR::WIF1 Fusion | Bevacizumab | Predictive | B | Supports Sensitivity Response | 2 | submitted | EID11104EGFR::WIF1 was identified by RNA-seq in a tumor sample derived from 1/78 recurrent glioblastoma patients in the BELOB clinical trial. The IDH-wildtype GBM tumor from this 59yo female patient belonged … (full text at CIViC) PMID 26762204 · Erdem-Eraslan et al., 2016 · Open in CIViC | civic |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available