Gene
WIF1
Wnt inhibitory factor 1
Explore in graph →CI-GENE-00038872HGNC:18081 ENSG00000156076 NCBI 11197 Approved
Curated evidence
Clinical evidence (1)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26762204
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| WIF1 Fusion1 | ||||||||
| Bevacizumab | IDH-wildtype GlioblastomaUNRESOLVED | Predictive | B | Supports Sensitivity Response | 2 | submitted | EID11104EGFR::WIF1 was identified by RNA-seq in a tumor sample derived from 1/78 recurrent glioblastoma patients in the BELOB clinical trial. The IDH-wildtype GBM tumor from this 59yo female patient belonged … (full text at CIViC) PMID 26762204 · Erdem-Eraslan et al., 2016 · Open in CIViC | civic |
Cohorts
Alteration frequency by cohort (0)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
Data not yet available
No cohort frequency recorded for this gene.
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.