Variant · Snv
A2M NM_000014.6(A2M):c.387C>G (p.Val129=)
CI-VAR-00126807Explore in graph →p.Val129=NM_000014.6:c.387C>GClinVar 777428 rs56202499
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 777428 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Colon adenocarcinoma; Clear cell carcinoma of kidney; Thymoma; Thyroid cancer, nonmedullary, 1; Melanoma; Acute myeloid leukemia; Colorectal cancer; Gastric cancer; Hepatocellular carcinoma; Lung cancer; Uveal melanoma; Sarcoma; Malignant tumor of esophagus | germline | 4 | Apr 01, 2024 | clinvar |