ASNS NM_001673.5(ASNS):c.146G>A (p.Arg49Gln)

CI-VAR-00056607Explore in graph →p.Arg49GlnNM_001673.5:c.146G>AClinVar 383733 rs769236847

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
383733	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Congenital microcephaly - severe encephalopathy - progressive cerebral atrophy syndrome; Neurodevelopmental delay; Pancreatic adenocarcinoma; ASNS-related disorder; Gastric cancer	germline	12	Nov 24, 2025	clinvar