Variant · Snv
PAK1 NM_002576.5(PAK1):c.291G>A (p.Thr97=)
CI-VAR-00338630Explore in graph →p.Thr97=NM_002576.5:c.291G>AClinVar 3038097 rs1130059
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 3038097 | Benign | no assertion criteria provided | 0 | PAK1-related disorder; Clear cell carcinoma of kidney; Uterine corpus endometrial carcinoma; Colon adenocarcinoma; Colorectal cancer; Gastric cancer; Uterine carcinosarcoma; Sarcoma; Thyroid cancer, nonmedullary, 1; Nonpapillary renal cell carcinoma; Lung cancer; Melanoma; Acute myeloid leukemia; Hepatocellular carcinoma; Malignant tumor of esophagus; Ovarian serous cystadenocarcinoma; Thymoma; Adrenocortical carcinoma, hereditary; Cervical cancer | germline | 2 | Feb 21, 2019 | clinvar |