Variant · Snv
ROBO3 NM_022370.4(ROBO3):c.2993G>T (p.Gly998Val)
CI-VAR-00052826Explore in graph →p.Gly998ValNM_022370.4:c.2993G>TClinVar 303263 rs75098003
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 303263 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Gaze palsy, familial horizontal, with progressive scoliosis 1; ROBO3-related disorder; Clear cell carcinoma of kidney; Malignant tumor of urinary bladder; Familial cancer of breast | germline | 5 | Nov 12, 2024 | clinvar |