Gene
ROBO3
roundabout guidance receptor 3
Explore in graph →CI-GENE-00027317HGNC:13433 ENSG00000154134 NCBI 64221 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| HIV+ Tumor Molecular Characterization Project - Diffuse Large B-Cell Lymphoma CGCI-HTMCP-DLBCL | Diffuse Large B-Cell LymphomaCURATED_BROADER | Ssm | 17 | 50 | 34% | 77 | gdc |
| Solitary Fibrous Tumors (SYSUCC, Nat Commun 2023) sft_sysucc_2023 | unmapped | Ssm | 6 | 131 | 4.6% | 47 | cbioportal |
| Ampullary Carcinoma (Baylor College of Medicine, Cell Reports 2016) ampca_bcm_2016 | Ampulla of Vater Carcinoma | Ssm | 7 | 160 | 4.4% | 188 | cbioportal |
| Cholangiocarcinoma (ICGC, Cancer Discov 2017) chol_icgc_2017 | Cholangiocarcinoma | Ssm | 16 | 417 | 3.8% | 65 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.