Variant · Snv
TJP1 NM_001330239.4(TJP1):c.2415G>A (p.Ala805=)
CI-VAR-00306160Explore in graph →p.Ala805=NM_001330239.4:c.2415G>AClinVar 2645098 rs147136553
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 2645098 | Likely benign | criteria provided, single submitter | 1 | TJP1-related disorder; Colon adenocarcinoma; Melanoma; Malignant tumor of esophagus; Lung cancer; Familial cancer of breast; Clear cell carcinoma of kidney; Malignant tumor of urinary bladder; Nonpapillary renal cell carcinoma; Gastric cancer; Ovarian serous cystadenocarcinoma; Uterine carcinosarcoma; Thyroid cancer, nonmedullary, 1 | germline | 3 | Nov 01, 2022 | clinvar |