Gene
TJP1
tight junction protein 1
Explore in graph →CI-GENE-00035226HGNC:11827 ENSG00000104067 NCBI 7082 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 35504881
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Cancer Brain Metastases (Bern, Nat Commun. 2022) prostate_pcbm_swiss_2019 | unmapped | Ssm | 14 | 168 | 8.3% | 71 | cbioportal |
| Diffuse Large B-Cell Lymphoma (Broad, PNAS 2012) dlbc_broad_2012 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 4 | 58 | 6.9% | 121 | cbioportal |
| The Metastatic Breast Cancer Project (Archived, 2020) brca_mbcproject_wagle_2017 | Invasive Breast Carcinoma | Ssm | 7 | 237 | 3% | 139 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.