NPHS1 NM_004646.4(NPHS1):c.3230A>G (p.Asn1077Ser)

CI-VAR-00047730Explore in graph →p.Asn1077SerNM_004646.4:c.3230A>GClinVar 259496 rs4806213

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
259496	Benign	criteria provided, multiple submitters, no conflicts	2	Finnish congenital nephrotic syndrome; Congenital nephrotic syndrome; Focal segmental glomerulosclerosis; Thymoma; Nonpapillary renal cell carcinoma	germline	15	Feb 04, 2026	clinvar